FI750652A - - Google Patents

Info

Publication number
FI750652A
FI750652A FI750652A FI750652A FI750652A FI 750652 A FI750652 A FI 750652A FI 750652 A FI750652 A FI 750652A FI 750652 A FI750652 A FI 750652A FI 750652 A FI750652 A FI 750652A
Authority
FI
Finland
Application number
FI750652A
Other versions
FI63571B (fi
FI63571C (fi
Inventor
Herbert Merz
Adolf Langbein
Gerhard Walther
Klaus Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of FI750652A publication Critical patent/FI750652A/fi
Publication of FI63571B publication Critical patent/FI63571B/fi
Application granted granted Critical
Publication of FI63571C publication Critical patent/FI63571C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI750652A 1974-03-09 1975-03-06 Foerfarande foer framstaellning av analgetiskt verkande racemiska eller diastereomera och optiskt aktiva 2-tetrahydrofurfuryl-(1r/s 5r/s 9r/s)-2'-hydroxi-5,9-dimetyl-6,7-bensomorfaner och deras syraadditionssalter FI63571C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung
DE2411382 1974-03-09

Publications (3)

Publication Number Publication Date
FI750652A true FI750652A (fi) 1975-09-10
FI63571B FI63571B (fi) 1983-03-31
FI63571C FI63571C (fi) 1983-07-11

Family

ID=5909593

Family Applications (1)

Application Number Title Priority Date Filing Date
FI750652A FI63571C (fi) 1974-03-09 1975-03-06 Foerfarande foer framstaellning av analgetiskt verkande racemiska eller diastereomera och optiskt aktiva 2-tetrahydrofurfuryl-(1r/s 5r/s 9r/s)-2'-hydroxi-5,9-dimetyl-6,7-bensomorfaner och deras syraadditionssalter

Country Status (25)

Country Link
JP (1) JPS5827275B2 (fi)
AT (1) AT344332B (fi)
BE (1) BE826440A (fi)
BG (3) BG24813A4 (fi)
CA (1) CA1049511A (fi)
CH (8) CH612425A5 (fi)
CS (1) CS188221B2 (fi)
DD (1) DD119236A5 (fi)
DE (1) DE2411382C3 (fi)
DK (1) DK137188C (fi)
ES (6) ES440345A1 (fi)
FI (1) FI63571C (fi)
FR (1) FR2262984B1 (fi)
GB (1) GB1496418A (fi)
HU (1) HU177408B (fi)
IE (1) IE40945B1 (fi)
IL (1) IL46760A (fi)
NL (1) NL7502724A (fi)
NO (1) NO141800C (fi)
PH (1) PH14127A (fi)
PL (3) PL93699B1 (fi)
RO (2) RO69617A (fi)
SE (1) SE421919B (fi)
SU (3) SU577982A3 (fi)
ZA (1) ZA751394B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
ATE202076T1 (de) * 1995-03-10 2001-06-15 Photocure Asa Ester der 5-aminolevulinsäure als mittel zur photosensibilisierung in der chemotherapie
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
AR067673A1 (es) 2007-07-26 2009-10-21 Vitae Pharmaceuticals Inc Derivados de 1,3 oxazinan - 2 - ona como inhibidores ciclicos de la 11 beta -hidroxiesteroide deshidrogenasa 1. composiciones farmaceuticas.
JP5769970B2 (ja) 2007-11-16 2015-08-26 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベンゾモルファン及び関連骨格のアリール−及びヘテロアリールカルボニル誘導体、かかる化合物を含有する医薬及びこれらの使用
CA2708303A1 (en) 2007-12-11 2009-06-18 Vitae Pharmaceuticals, Inc. Cyclic urea inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
JP5490020B2 (ja) 2008-01-24 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状カルバゼート及びセミカルバジドインヒビター
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ588954A (en) 2008-05-01 2012-08-31 Vitae Pharmaceuticals Inc Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071236A1 (es) 2008-05-01 2010-06-02 Vitae Pharmaceuticals Inc Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8765780B2 (en) 2008-05-13 2014-07-01 Boehringer Ingelheim International Gmbh Alicyclic carboxylic acid derivatives of benzomorphans and related scaffolds, medicaments containing such compounds and their use
CN102119160B (zh) 2008-07-25 2014-11-05 贝林格尔·英格海姆国际有限公司 11β-羟基类固醇脱氢酶1的环状抑制剂
JP5777030B2 (ja) 2008-07-25 2015-09-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5656986B2 (ja) 2009-06-11 2015-01-21 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １，３−オキサジナン−２−オン構造に基づく１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
EP2582698B1 (en) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体

Also Published As

Publication number Publication date
DE2411382C3 (de) 1979-09-06
IL46760A0 (en) 1975-05-22
ES440347A1 (es) 1977-06-01
AT344332B (de) 1978-07-10
CH620439A5 (en) 1980-11-28
ES440348A1 (es) 1977-06-01
IE40945B1 (en) 1979-09-12
CH620440A5 (en) 1980-11-28
NO750773L (fi) 1975-09-10
RO69617A (ro) 1980-08-15
DE2411382A1 (de) 1975-09-18
BG24814A4 (en) 1978-05-12
PL93499B1 (fi) 1977-05-30
JPS50123675A (fi) 1975-09-29
CH622014A5 (en) 1981-03-13
AU7894275A (en) 1976-09-16
ZA751394B (en) 1976-11-24
NO141800B (no) 1980-02-04
BG25087A3 (en) 1978-07-12
NO141800C (no) 1980-06-04
SE421919B (sv) 1982-02-08
NL7502724A (nl) 1975-09-11
SU577982A3 (ru) 1977-10-25
CH620681A5 (en) 1980-12-15
FI63571B (fi) 1983-03-31
ES440345A1 (es) 1977-03-01
HU177408B (en) 1981-10-28
ATA153875A (de) 1977-11-15
SU577983A3 (ru) 1977-10-25
DE2411382B2 (de) 1979-01-18
CH622016A5 (en) 1981-03-13
DD119236A5 (fi) 1976-04-12
SE7502592L (fi) 1975-09-10
PH14127A (en) 1981-02-26
JPS5827275B2 (ja) 1983-06-08
ES440350A1 (es) 1977-03-16
IL46760A (en) 1978-12-17
IE40945L (en) 1975-09-09
GB1496418A (en) 1977-12-30
DK92975A (fi) 1975-09-10
DK137188B (da) 1978-01-30
ES440346A1 (es) 1977-03-01
RO70051A (ro) 1980-12-30
BE826440A (fr) 1975-09-08
FR2262984B1 (fi) 1978-07-28
CH622015A5 (en) 1981-03-13
CA1049511A (en) 1979-02-27
FR2262984A1 (fi) 1975-10-03
CH612425A5 (en) 1979-07-31
PL93700B1 (fi) 1977-06-30
SU588916A3 (ru) 1978-01-15
BG24813A4 (en) 1978-05-12
DK137188C (da) 1978-07-03
PL93699B1 (fi) 1977-06-30
CS188221B2 (en) 1979-02-28
ES440349A1 (es) 1977-03-01
CH622017A5 (en) 1981-03-13
FI63571C (fi) 1983-07-11

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: C.H. BOEHRINGER SOHN