ES440345A1 - Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos. - Google Patents

Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.

Info

Publication number
ES440345A1
ES440345A1 ES440345A ES440345A ES440345A1 ES 440345 A1 ES440345 A1 ES 440345A1 ES 440345 A ES440345 A ES 440345A ES 440345 A ES440345 A ES 440345A ES 440345 A1 ES440345 A1 ES 440345A1
Authority
ES
Spain
Prior art keywords
methyl
formula
action
denotes hydrogen
morphine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES440345A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES440345A1 publication Critical patent/ES440345A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ES440345A 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos. Expired ES440345A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2411382A DE2411382C3 (de) 1974-03-09 1974-03-09 2-Tetrahydrofurfuryl-6,7-benzomorphane, Verfahren zur Herstellung und deren Verwendung

Publications (1)

Publication Number Publication Date
ES440345A1 true ES440345A1 (es) 1977-03-01

Family

ID=5909593

Family Applications (6)

Application Number Title Priority Date Filing Date
ES440348A Expired ES440348A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440350A Expired ES440350A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440349A Expired ES440349A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440345A Expired ES440345A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440347A Expired ES440347A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440346A Expired ES440346A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES440348A Expired ES440348A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440350A Expired ES440350A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440349A Expired ES440349A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES440347A Expired ES440347A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.
ES440346A Expired ES440346A1 (es) 1974-03-09 1975-08-20 Procedimiento para la preparacion de 2-tetrahidrofurfuril-6,7-benzomorfanos.

Country Status (25)

Country Link
JP (1) JPS5827275B2 (fi)
AT (1) AT344332B (fi)
BE (1) BE826440A (fi)
BG (3) BG25087A3 (fi)
CA (1) CA1049511A (fi)
CH (8) CH612425A5 (fi)
CS (1) CS188221B2 (fi)
DD (1) DD119236A5 (fi)
DE (1) DE2411382C3 (fi)
DK (1) DK137188C (fi)
ES (6) ES440348A1 (fi)
FI (1) FI63571C (fi)
FR (1) FR2262984B1 (fi)
GB (1) GB1496418A (fi)
HU (1) HU177408B (fi)
IE (1) IE40945B1 (fi)
IL (1) IL46760A (fi)
NL (1) NL7502724A (fi)
NO (1) NO141800C (fi)
PH (1) PH14127A (fi)
PL (3) PL93700B1 (fi)
RO (2) RO69617A (fi)
SE (1) SE421919B (fi)
SU (3) SU577982A3 (fi)
ZA (1) ZA751394B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US7530461B2 (en) 1995-03-10 2009-05-12 Photocure Asa Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6492420B2 (en) 1995-03-10 2002-12-10 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
US6992107B1 (en) 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
CA2215069C (en) * 1995-03-10 2006-09-12 Photocure As Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
GB0018528D0 (en) 2000-07-27 2000-09-13 Photocure Asa Compounds
US6723750B2 (en) 2002-03-15 2004-04-20 Allergan, Inc. Photodynamic therapy for pre-melanomas
JP5470557B2 (ja) 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
CL2008003407A1 (es) 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US8592409B2 (en) 2008-01-24 2013-11-26 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
CA2715290A1 (en) 2008-02-15 2009-08-20 Vitae Pharmaceuticals, Inc. Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8138178B2 (en) 2008-05-01 2012-03-20 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8569292B2 (en) 2008-05-01 2013-10-29 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
WO2009134387A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071719A1 (es) 2008-05-13 2010-07-07 Boehringer Ingelheim Int Derivados aliciclicos de acido carboxilico de benzomorfanos y estructuras relacionadas, medicamentos que contienen dichos compuestos y su uso.procesos de obtencion
NZ590495A (en) 2008-07-25 2012-10-26 Vitae Pharmaceuticals Inc Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
UY33001A (es) 2009-11-06 2011-05-31 Boehringer Ingelheim Int Derivados arilo y heteroarilcarbonilo de hexahidroindenopiridina y octahidrobenzoquinolina
US8933072B2 (en) 2010-06-16 2015-01-13 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Also Published As

Publication number Publication date
ES440349A1 (es) 1977-03-01
IL46760A0 (en) 1975-05-22
SU588916A3 (ru) 1978-01-15
FI63571B (fi) 1983-03-31
GB1496418A (en) 1977-12-30
PL93700B1 (fi) 1977-06-30
BG24814A4 (en) 1978-05-12
CA1049511A (en) 1979-02-27
BE826440A (fr) 1975-09-08
BG25087A3 (en) 1978-07-12
ZA751394B (en) 1976-11-24
SE421919B (sv) 1982-02-08
CH620439A5 (en) 1980-11-28
FI750652A (fi) 1975-09-10
AU7894275A (en) 1976-09-16
IE40945L (en) 1975-09-09
DK137188B (da) 1978-01-30
CH612425A5 (en) 1979-07-31
RO70051A (ro) 1980-12-30
CH622016A5 (en) 1981-03-13
NO750773L (fi) 1975-09-10
CS188221B2 (en) 1979-02-28
FR2262984A1 (fi) 1975-10-03
NO141800B (no) 1980-02-04
ATA153875A (de) 1977-11-15
HU177408B (en) 1981-10-28
NO141800C (no) 1980-06-04
PL93699B1 (fi) 1977-06-30
RO69617A (ro) 1980-08-15
ES440346A1 (es) 1977-03-01
DK137188C (da) 1978-07-03
SU577982A3 (ru) 1977-10-25
DD119236A5 (fi) 1976-04-12
ES440347A1 (es) 1977-06-01
PL93499B1 (fi) 1977-05-30
SU577983A3 (ru) 1977-10-25
CH620681A5 (en) 1980-12-15
PH14127A (en) 1981-02-26
AT344332B (de) 1978-07-10
CH622015A5 (en) 1981-03-13
CH622014A5 (en) 1981-03-13
DK92975A (fi) 1975-09-10
JPS50123675A (fi) 1975-09-29
IE40945B1 (en) 1979-09-12
ES440348A1 (es) 1977-06-01
NL7502724A (nl) 1975-09-11
CH622017A5 (en) 1981-03-13
IL46760A (en) 1978-12-17
DE2411382B2 (de) 1979-01-18
BG24813A4 (en) 1978-05-12
DE2411382A1 (de) 1975-09-18
JPS5827275B2 (ja) 1983-06-08
CH620440A5 (en) 1980-11-28
DE2411382C3 (de) 1979-09-06
ES440350A1 (es) 1977-03-16
FI63571C (fi) 1983-07-11
FR2262984B1 (fi) 1978-07-28
SE7502592L (fi) 1975-09-10

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