FI71127C - Foerfarande foer framstaellning av som hjaertlaekemedel anvaendbara 2,2,5,5-tetrametylpyrrolin- och -pyrrolidin-3-karboxylsyraamidderivat - Google Patents

Foerfarande foer framstaellning av som hjaertlaekemedel anvaendbara 2,2,5,5-tetrametylpyrrolin- och -pyrrolidin-3-karboxylsyraamidderivat Download PDF

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Publication number
FI71127C
FI71127C FI843667A FI843667A FI71127C FI 71127 C FI71127 C FI 71127C FI 843667 A FI843667 A FI 843667A FI 843667 A FI843667 A FI 843667A FI 71127 C FI71127 C FI 71127C
Authority
FI
Finland
Prior art keywords
group
general formula
compounds
carbon atoms
derivatives
Prior art date
Application number
FI843667A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI843667L (fi
FI843667A0 (fi
FI71127B (fi
Inventor
Kalman Hideg
Olga Hankovszky
Laszlo Frank
Ilona Bodi
Jozsef Csak
Original Assignee
Alkaloida Vegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alkaloida Vegyeszeti Gyar filed Critical Alkaloida Vegyeszeti Gyar
Publication of FI843667L publication Critical patent/FI843667L/fi
Publication of FI843667A0 publication Critical patent/FI843667A0/fi
Application granted granted Critical
Publication of FI71127B publication Critical patent/FI71127B/fi
Publication of FI71127C publication Critical patent/FI71127C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
FI843667A 1983-01-20 1984-09-19 Foerfarande foer framstaellning av som hjaertlaekemedel anvaendbara 2,2,5,5-tetrametylpyrrolin- och -pyrrolidin-3-karboxylsyraamidderivat FI71127C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
HU83178A HU189214B (en) 1983-01-20 1983-01-20 Process for preparing pyrroline and pyrrolidine carboxamide derivatives
HU17883 1983-01-20
PCT/HU1984/000004 WO1984002906A1 (en) 1983-01-20 1984-01-20 New amino derivatives of 2- adn-(2,2,5,5-tetramethyl-3-pyrrolin-3-carbonyl) bd
HU8400004 1984-01-20

Publications (4)

Publication Number Publication Date
FI843667L FI843667L (fi) 1984-09-19
FI843667A0 FI843667A0 (fi) 1984-09-19
FI71127B FI71127B (fi) 1986-08-14
FI71127C true FI71127C (fi) 1986-11-24

Family

ID=10948332

Family Applications (1)

Application Number Title Priority Date Filing Date
FI843667A FI71127C (fi) 1983-01-20 1984-09-19 Foerfarande foer framstaellning av som hjaertlaekemedel anvaendbara 2,2,5,5-tetrametylpyrrolin- och -pyrrolidin-3-karboxylsyraamidderivat

Country Status (9)

Country Link
US (1) US4731376A (ja)
EP (1) EP0134795B1 (ja)
JP (1) JPS60500668A (ja)
DE (1) DE3473443D1 (ja)
DK (1) DK166776B1 (ja)
FI (1) FI71127C (ja)
HU (1) HU189214B (ja)
SU (1) SU1333236A3 (ja)
WO (1) WO1984002906A1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0134225B1 (en) * 1983-01-21 1988-08-17 ALKALOIDA VEGYéSZETI GYáR New alkyl diamine derivatives
US5047555A (en) * 1988-12-13 1991-09-10 Tanabe Seiyaku Co., Ltd. 4-aminophenol derivatives and processes for preparing the same
HUP9700392A1 (hu) * 1997-02-10 1999-09-28 ICN Magyarország Részvénytársaság Egy vagy két hatóanyagot tartalmazó kardioprotektív hatású gyógyszerkészítmények
TWI243162B (en) * 2000-11-10 2005-11-11 Taisho Pharmaceutical Co Ltd Cyanopyrrolidine derivatives
US6827226B2 (en) * 2002-12-09 2004-12-07 Wmc Holdings Incorporated Storage apparatus for sportboards with variable widths
HUE029393T2 (en) 2010-08-31 2017-03-28 Bionure Farma S L Neurotrophin receptor agonists and their use as medicaments
WO2017038552A1 (ja) * 2015-09-04 2017-03-09 Dic株式会社 安定剤化合物、液晶組成物および表示素子
JP6358398B2 (ja) 2015-09-04 2018-07-18 Dic株式会社 液晶組成物及びそれを使用した液晶表示素子

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE109346C (ja) *
US3020288A (en) * 1962-02-06 Hypotensive compounds
DE109345C (ja) *
DE109347C (ja) *
GB190004799A (en) * 1900-03-13 1900-05-19 George William Johnson The Manufacture of Para-amidophenyl Glyoxylic Acid, its Substitution Products and Homologues.
CH336068A (de) * 1955-04-06 1959-02-15 Bofors Ab Verfahren zur Herstellung von Amiden von N-Alkyl-piperidin-monocarbonsäuren oder N-Alkyl-pyrrolidin-a-monocarbonsäuren
GB983134A (en) * 1962-06-13 1965-02-10 American Cyanamid Co Cyclic nitroxides and process for preparing same
US3250771A (en) * 1962-12-17 1966-05-10 Geigy Chem Corp 5-monocarbocyclic aryl-n-lower alkyl-2-pyrrolidine carboxylic acid, esters, amides and derivatives thereof
US3299097A (en) * 1963-04-29 1967-01-17 Upjohn Co 4-alkylhygric acid hydrazides
US3313801A (en) * 1965-10-18 1967-04-11 Upjohn Co Process for inhibiting n-alkylation of pyrrolidines and substituted pyrrolidines by microorganisms, and products produced thereby
US3624081A (en) * 1967-02-15 1971-11-30 Sterling Drug Inc 1-acyl-2-ethylidenepyrrol-idine-3-carboxamides
US4111901A (en) * 1977-06-06 1978-09-05 Borg-Warner Corporation Hindered five-membered nitrogen rings as polyolefin stabilizers
US4302383A (en) * 1980-05-19 1981-11-24 Borg-Warner Chemicals, Inc. Stabilized olefin polymers

Also Published As

Publication number Publication date
FI843667L (fi) 1984-09-19
HU189214B (en) 1986-06-30
DK166776B1 (da) 1993-07-12
WO1984002906A1 (en) 1984-08-02
DK447284D0 (da) 1984-09-19
DK447284A (da) 1984-11-20
FI843667A0 (fi) 1984-09-19
US4731376A (en) 1988-03-15
DE3473443D1 (en) 1988-09-22
FI71127B (fi) 1986-08-14
EP0134795A1 (en) 1985-03-27
SU1333236A3 (ru) 1987-08-23
EP0134795B1 (de) 1988-08-17
JPH0471067B2 (ja) 1992-11-12
JPS60500668A (ja) 1985-05-09

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Owner name: ALKALOIDA VEGYéSZETI GYAR