FI69463C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara kinolylguanidiner - Google Patents
Foerfarande foer framstaellning av nya terapeutiskt anvaendbara kinolylguanidiner Download PDFInfo
- Publication number
- FI69463C FI69463C FI783327A FI783327A FI69463C FI 69463 C FI69463 C FI 69463C FI 783327 A FI783327 A FI 783327A FI 783327 A FI783327 A FI 783327A FI 69463 C FI69463 C FI 69463C
- Authority
- FI
- Finland
- Prior art keywords
- formula
- halogen
- alkyl
- compound
- trifluoromethyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Pain & Pain Management (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB4616677 | 1977-11-07 | ||
GB4616677 | 1977-11-07 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI783327A FI783327A (fi) | 1979-05-08 |
FI69463B FI69463B (fi) | 1985-10-31 |
FI69463C true FI69463C (fi) | 1986-02-10 |
Family
ID=10440127
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI783327A FI69463C (fi) | 1977-11-07 | 1978-11-01 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara kinolylguanidiner |
Country Status (24)
Country | Link |
---|---|
US (1) | US4293549A (el) |
JP (1) | JPS5473784A (el) |
AT (1) | AT366368B (el) |
AU (1) | AU517670B2 (el) |
BE (1) | BE871807A (el) |
CA (1) | CA1120929A (el) |
CH (1) | CH645354A5 (el) |
DE (1) | DE2847792A1 (el) |
DK (1) | DK153950C (el) |
ES (1) | ES474900A1 (el) |
FI (1) | FI69463C (el) |
FR (1) | FR2407930A1 (el) |
GR (1) | GR65010B (el) |
IE (1) | IE47458B1 (el) |
IT (1) | IT1100075B (el) |
LU (1) | LU80476A1 (el) |
NL (1) | NL7811035A (el) |
NZ (1) | NZ188770A (el) |
PH (1) | PH16296A (el) |
PT (1) | PT68750A (el) |
SE (1) | SE446267B (el) |
SU (1) | SU828967A3 (el) |
YU (1) | YU41129B (el) |
ZA (1) | ZA786175B (el) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306846B1 (en) * | 1972-05-31 | 2001-10-23 | John R. J. Sorenson | Anti-inflammatory and anti-ulcer compounds and process |
IT1205640B (it) * | 1983-04-06 | 1989-03-23 | Yason Srl | Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono |
US4563460A (en) * | 1984-01-13 | 1986-01-07 | William H. Rorer, Inc. | Quinoline and quinazoline derivatives for treating gastrointestinal motility dysfunctions |
HU195487B (en) * | 1985-06-04 | 1988-05-30 | Egyt Gyogyszervegyeszeti Gyar | Process for producing quinoline derivatives |
ATE66477T1 (de) * | 1986-08-29 | 1991-09-15 | Pfizer | 2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren. |
US6100260A (en) * | 1997-04-21 | 2000-08-08 | Sumitomo Pharmaceutical Company, Limited | Isoxazole derivatives |
SI0928793T1 (en) * | 1998-01-02 | 2002-10-31 | F. Hoffmann-La Roche Ag | Thiazole derivatives |
BR9909666A (pt) | 1998-03-26 | 2001-09-11 | Japan Tobacco Inc | Derivados de amida e antagonistas de nociceptina |
JP2003513064A (ja) * | 1999-11-05 | 2003-04-08 | ユニバーシティ カレッジ ロンドン | 可溶性グアニル酸シクラーゼのアクチベーター |
WO2004063181A1 (en) * | 2003-01-03 | 2004-07-29 | Genzyme Corporation | Urea derivatives and their use as anti-inflammatory agents |
MXPA05007513A (es) * | 2003-01-14 | 2005-09-21 | Cytokinetics Inc | Compuestos, composiciones y metodos. |
GB0404434D0 (en) | 2004-02-27 | 2004-03-31 | Novartis Ag | Organic compounds |
WO2007022964A2 (de) * | 2005-08-24 | 2007-03-01 | Abbott Gmbh & Co. Kg | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
WO2023003497A1 (ru) * | 2021-07-23 | 2023-01-26 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Соединения с лизосомотропной и противовирусной активностью |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB889282A (en) * | 1957-05-07 | 1962-02-14 | Air Reduction | Preparation of hexafluorodiethyl ether and medicinal compositions containing it |
GB889262A (en) * | 1959-07-03 | 1962-02-14 | Ciba Ltd | Quinoline compounds |
US3159676A (en) * | 1962-02-07 | 1964-12-01 | Smith Kline French Lab | Naphthyl containing guanidines |
US3852293A (en) | 1972-06-21 | 1974-12-03 | Uniroyal Inc | 4-phenyl-2-(3-pyridyl)-thiazole carboxamides |
US4000279A (en) * | 1974-10-29 | 1976-12-28 | Armour Pharmaceutical Company | Pharmaceutical preparations containing 5'-(8'-hydroxyquinolyl)guanidine compounds and methods of using same |
-
1978
- 1978-10-20 IE IE2084/78A patent/IE47458B1/en not_active IP Right Cessation
- 1978-10-26 GR GR57518A patent/GR65010B/el unknown
- 1978-10-27 US US05/955,228 patent/US4293549A/en not_active Expired - Lifetime
- 1978-10-30 AT AT0773278A patent/AT366368B/de not_active IP Right Cessation
- 1978-10-30 NZ NZ188770A patent/NZ188770A/en unknown
- 1978-10-31 CA CA000315384A patent/CA1120929A/en not_active Expired
- 1978-11-01 FI FI783327A patent/FI69463C/fi not_active IP Right Cessation
- 1978-11-02 PH PH21790A patent/PH16296A/en unknown
- 1978-11-02 ZA ZA00786175A patent/ZA786175B/xx unknown
- 1978-11-03 CH CH1136378A patent/CH645354A5/de not_active IP Right Cessation
- 1978-11-03 DE DE19782847792 patent/DE2847792A1/de active Granted
- 1978-11-04 SU SU782685598A patent/SU828967A3/ru active
- 1978-11-06 SE SE7811457A patent/SE446267B/sv not_active IP Right Cessation
- 1978-11-06 AU AU41376/78A patent/AU517670B2/en not_active Expired
- 1978-11-06 FR FR7831339A patent/FR2407930A1/fr active Granted
- 1978-11-06 YU YU2575/78A patent/YU41129B/xx unknown
- 1978-11-06 PT PT68750A patent/PT68750A/pt unknown
- 1978-11-06 NL NL7811035A patent/NL7811035A/xx not_active Application Discontinuation
- 1978-11-06 JP JP13723578A patent/JPS5473784A/ja active Granted
- 1978-11-06 DK DK493378A patent/DK153950C/da not_active IP Right Cessation
- 1978-11-06 LU LU80476A patent/LU80476A1/xx unknown
- 1978-11-06 BE BE191566A patent/BE871807A/xx not_active IP Right Cessation
- 1978-11-07 IT IT29514/78A patent/IT1100075B/it active
- 1978-11-07 ES ES474900A patent/ES474900A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
PT68750A (en) | 1978-12-01 |
DE2847792A1 (de) | 1979-05-10 |
PH16296A (en) | 1983-09-05 |
ATA773278A (de) | 1981-08-15 |
DK153950B (da) | 1988-09-26 |
IE47458B1 (en) | 1984-03-21 |
FR2407930B1 (el) | 1983-03-18 |
AU517670B2 (en) | 1981-08-20 |
YU41129B (en) | 1986-12-31 |
NL7811035A (nl) | 1979-05-09 |
IT1100075B (it) | 1985-09-28 |
SE7811457L (sv) | 1979-05-08 |
FI783327A (fi) | 1979-05-08 |
IE782084L (en) | 1979-05-07 |
GR65010B (en) | 1980-06-12 |
SE446267B (sv) | 1986-08-25 |
JPS5473784A (en) | 1979-06-13 |
ZA786175B (en) | 1979-10-31 |
DK153950C (da) | 1989-02-20 |
DE2847792C2 (el) | 1988-02-04 |
YU257578A (en) | 1983-01-21 |
SU828967A3 (ru) | 1981-05-07 |
CA1120929A (en) | 1982-03-30 |
AT366368B (de) | 1982-04-13 |
FI69463B (fi) | 1985-10-31 |
LU80476A1 (fr) | 1979-06-15 |
BE871807A (fr) | 1979-05-07 |
US4293549A (en) | 1981-10-06 |
CH645354A5 (de) | 1984-09-28 |
NZ188770A (en) | 1984-07-31 |
ES474900A1 (es) | 1980-04-16 |
AU4137678A (en) | 1979-05-17 |
FR2407930A1 (fr) | 1979-06-01 |
IT7829514A0 (it) | 1978-11-07 |
DK493378A (da) | 1979-05-08 |
JPS6348873B2 (el) | 1988-09-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed |
Owner name: LEO PHARMACEUTICAL PRODUCTS LTD A/S (LOEVENS KEMIS |