FI68612C - Foerfarande foer framstaellning av antibakteriellt och/eller antimalariskt aktiva 2,4 -diamino-5-bensylpyrimidiner samt vi foerfarandet anvaendbar bensylcyanacetal - Google Patents

Foerfarande foer framstaellning av antibakteriellt och/eller antimalariskt aktiva 2,4 -diamino-5-bensylpyrimidiner samt vi foerfarandet anvaendbar bensylcyanacetal Download PDF

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Publication number
FI68612C
FI68612C FI771816A FI771816A FI68612C FI 68612 C FI68612 C FI 68612C FI 771816 A FI771816 A FI 771816A FI 771816 A FI771816 A FI 771816A FI 68612 C FI68612 C FI 68612C
Authority
FI
Finland
Prior art keywords
benzyl
cyanoacetal
formula
group
diamino
Prior art date
Application number
FI771816A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI68612B (fi
FI771816A (fr
Inventor
David Arthur Yeowell
Jr Roy Archibald Swaringen
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI771816A publication Critical patent/FI771816A/fi
Application granted granted Critical
Publication of FI68612B publication Critical patent/FI68612B/fi
Publication of FI68612C publication Critical patent/FI68612C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01G—HORTICULTURE; CULTIVATION OF VEGETABLES, FLOWERS, RICE, FRUIT, VINES, HOPS OR SEAWEED; FORESTRY; WATERING
    • A01G5/00—Floral handling
    • A01G5/04—Mountings for wreaths, or the like; Racks or holders for flowers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/27—Preparation of carboxylic acid esters from ortho-esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI771816A 1976-06-09 1977-06-08 Foerfarande foer framstaellning av antibakteriellt och/eller antimalariskt aktiva 2,4 -diamino-5-bensylpyrimidiner samt vi foerfarandet anvaendbar bensylcyanacetal FI68612C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB23756/76A GB1582245A (en) 1976-06-09 1976-06-09 Benzyl cyanoacetal derivatives and their conversion to pyrimidine derivatives
GB2375676 1976-06-09

Publications (3)

Publication Number Publication Date
FI771816A FI771816A (fr) 1977-12-10
FI68612B FI68612B (fi) 1985-06-28
FI68612C true FI68612C (fi) 1985-10-10

Family

ID=10200818

Family Applications (1)

Application Number Title Priority Date Filing Date
FI771816A FI68612C (fi) 1976-06-09 1977-06-08 Foerfarande foer framstaellning av antibakteriellt och/eller antimalariskt aktiva 2,4 -diamino-5-bensylpyrimidiner samt vi foerfarandet anvaendbar bensylcyanacetal

Country Status (19)

Country Link
US (2) US4144263A (fr)
JP (2) JPS5826908B2 (fr)
AT (1) AT350537B (fr)
AU (1) AU510298B2 (fr)
BE (1) BE855505A (fr)
CA (2) CA1091672A (fr)
CH (1) CH632239A5 (fr)
DE (1) DE2725992C2 (fr)
DK (1) DK254077A (fr)
FI (1) FI68612C (fr)
FR (1) FR2354317A1 (fr)
GB (1) GB1582245A (fr)
GR (1) GR63824B (fr)
HU (2) HU178138B (fr)
IL (1) IL52278A (fr)
NL (1) NL172541C (fr)
NZ (1) NZ184330A (fr)
SE (1) SE7706655L (fr)
ZA (1) ZA773466B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4438267A (en) * 1980-11-11 1984-03-20 Daluge Susan M Monoheteroring compounds and their use
JPS62188328A (ja) * 1986-02-14 1987-08-17 Toshiba Seiki Kk ペレツト装着装置
JPH01152656A (ja) * 1987-12-09 1989-06-15 Sanken Electric Co Ltd リードフレームへのスクリーン印刷方法
FI895821A0 (fi) * 1988-12-07 1989-12-05 Wellcome Found Farmaceutiskt aktiva cns foereningar.
KR100822530B1 (ko) 2004-03-05 2008-04-16 에프. 호프만-라 로슈 아게 Ｐ2ｘ3 및 ｐ2ｘ2/3 길항물질로서의 다이아미노피리미딘
JP4850913B2 (ja) * 2005-09-01 2012-01-11 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ３及びｐ２ｘ２／３調節因子としてのジアミノピリジン
CN101253159B (zh) * 2005-09-01 2011-12-07 弗·哈夫曼-拉罗切有限公司 作为p2x3和p2x2/3调节剂的二氨基嘧啶类化合物
EP1924564B1 (fr) * 2005-09-01 2016-11-09 F.Hoffmann-La Roche Ag Diaminopyrimidines en tant que modulateurs de p2x3 et p2x2/3

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2579259A (en) * 1951-12-18 Iamino-s-
US2755298A (en) * 1956-07-17 pwiiq
US2576939A (en) * 1951-12-04 -diamino-s-phenyl-e-alkyl-
US3485840A (en) * 1964-11-12 1969-12-23 Hoffmann La Roche 2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes
GB1142654A (en) * 1965-10-28 1969-02-12 Wellcome Found Cyano-acetals and their use in benzylpyrimidine synthesis
US3772289A (en) * 1970-10-22 1973-11-13 Burroughs Wellcome Co Alkyl substituted benzyl pyrimidines
BE795023A (fr) * 1972-02-07 1973-08-06 Hoffmann La Roche Nouvelles benzylpyrimidines

Also Published As

Publication number Publication date
IL52278A0 (en) 1977-08-31
JPS57136577A (en) 1982-08-23
BE855505A (fr) 1977-12-08
DE2725992A1 (de) 1977-12-29
US4216319A (en) 1980-08-05
US4144263A (en) 1979-03-13
DE2725992C2 (de) 1983-02-17
ZA773466B (en) 1978-04-26
HU178138B (en) 1982-03-28
NL172541B (nl) 1983-04-18
DK254077A (da) 1977-12-10
GB1582245A (en) 1981-01-07
JPS5826908B2 (ja) 1983-06-06
NL7706284A (nl) 1977-12-13
AU510298B2 (en) 1980-06-19
AU2591777A (en) 1978-12-14
FR2354317B1 (fr) 1980-02-01
NZ184330A (en) 1979-03-28
SE7706655L (sv) 1977-12-10
NL172541C (nl) 1983-09-16
CA1091672A (fr) 1980-12-16
JPS52151145A (en) 1977-12-15
IL52278A (en) 1981-07-31
ATA405777A (de) 1978-11-15
FI68612B (fi) 1985-06-28
JPS6049633B2 (ja) 1985-11-02
FR2354317A1 (fr) 1978-01-06
GR63824B (en) 1979-12-19
AT350537B (de) 1979-06-11
FI771816A (fr) 1977-12-10
CA1091673A (fr) 1980-12-16
CH632239A5 (de) 1982-09-30
HU178806B (en) 1982-06-28

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