FI66007C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara cefalosporinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara cefalosporinderivat Download PDF

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Publication number
FI66007C
FI66007C FI783960A FI783960A FI66007C FI 66007 C FI66007 C FI 66007C FI 783960 A FI783960 A FI 783960A FI 783960 A FI783960 A FI 783960A FI 66007 C FI66007 C FI 66007C
Authority
FI
Finland
Prior art keywords
formula
ppm
amino
syn
acid
Prior art date
Application number
FI783960A
Other languages
English (en)
Finnish (fi)
Other versions
FI66007B (fi
FI783960A (fi
Inventor
Juergen Blumbach
Walter Duerckheimer
Elmar Schrinner
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI783960A publication Critical patent/FI783960A/fi
Application granted granted Critical
Publication of FI66007B publication Critical patent/FI66007B/fi
Publication of FI66007C publication Critical patent/FI66007C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI783960A 1977-12-24 1978-12-21 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara cefalosporinderivat FI66007C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2758001 1977-12-24
DE19772758001 DE2758001A1 (de) 1977-12-24 1977-12-24 Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (3)

Publication Number Publication Date
FI783960A FI783960A (fi) 1979-06-25
FI66007B FI66007B (fi) 1984-04-30
FI66007C true FI66007C (fi) 1984-08-10

Family

ID=6027279

Family Applications (1)

Application Number Title Priority Date Filing Date
FI783960A FI66007C (fi) 1977-12-24 1978-12-21 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara cefalosporinderivat

Country Status (20)

Country Link
US (1) US4293550A (xx)
EP (1) EP0002765B1 (xx)
JP (1) JPS5495592A (xx)
AT (1) AT365599B (xx)
AU (1) AU534258B2 (xx)
CA (1) CA1109461A (xx)
DE (2) DE2758001A1 (xx)
DK (1) DK578978A (xx)
EG (1) EG13762A (xx)
ES (1) ES476109A1 (xx)
FI (1) FI66007C (xx)
GR (1) GR65234B (xx)
HU (1) HU184140B (xx)
IE (1) IE48147B1 (xx)
IL (1) IL56284A (xx)
NO (1) NO784366L (xx)
NZ (1) NZ189266A (xx)
PH (1) PH15925A (xx)
PT (1) PT68964A (xx)
ZA (1) ZA787209B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
NL8005440A (nl) * 1979-10-02 1981-04-06 Glaxo Group Ltd Cefalosporinen met antibiotische werking.
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
EP0055465B1 (en) 1980-12-31 1989-08-23 Fujisawa Pharmaceutical Co., Ltd. 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
JPS57131794A (en) * 1980-12-31 1982-08-14 Fujisawa Pharmaceut Co Ltd Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent
US4427677A (en) * 1980-12-31 1984-01-24 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
US4618606A (en) * 1982-11-17 1986-10-21 Toyama Chemical Co., Ltd. Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins
EP1059293A1 (en) * 1995-10-12 2000-12-13 Microcide Pharmaceuticals, Inc. Novel amino chlorothiazole compounds
IT1295935B1 (it) * 1997-10-30 1999-05-28 Acs Dobfar Spa Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici
TWI335332B (en) * 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
JP5491421B2 (ja) 2008-03-04 2014-05-14 アリーナ ファーマシューティカルズ， インコーポレイテッド ５−ｈｔ２ｃアゴニストである（ｒ）−８−クロロ−１−メチル−２，３，４，５−テトラヒドロ−１ｈ−３−ベンゾアゼピンに関連する中間体の調製のためのプロセス
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
EP2939677A1 (en) 2010-09-01 2015-11-04 Arena Pharmaceuticals, Inc. Administration of lorcaserin to indviduals with renal impairment
KR20130101524A (ko) 2010-09-01 2013-09-13 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 아고니스트의 비-흡습성 염
WO2012030938A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
AU2011296003B2 (en) 2010-09-01 2015-11-12 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-HT2C agonist useful for weight management
KR20190128001A (ko) 2012-10-09 2019-11-13 에자이 알앤드디 매니지먼트 가부시키가이샤 체중 관리 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5168589A (xx) * 1974-12-06 1976-06-14 Shionogi Seiyaku Kk
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Also Published As

Publication number Publication date
AU534258B2 (en) 1984-01-12
PT68964A (de) 1979-01-01
IL56284A0 (en) 1979-03-12
HU184140B (en) 1984-07-30
DE2861043D1 (en) 1981-11-26
DE2758001A1 (de) 1979-07-12
NZ189266A (en) 1981-12-15
EP0002765B1 (de) 1981-09-02
IL56284A (en) 1983-03-31
EP0002765A1 (de) 1979-07-11
AU4284878A (en) 1979-06-28
ES476109A1 (es) 1979-10-16
ZA787209B (en) 1979-12-27
JPH0132226B2 (xx) 1989-06-29
PH15925A (en) 1983-04-26
GR65234B (en) 1980-07-30
DK578978A (da) 1979-06-25
IE782546L (en) 1979-06-24
CA1109461A (en) 1981-09-22
US4293550A (en) 1981-10-06
FI66007B (fi) 1984-04-30
AT365599B (de) 1982-01-25
JPS5495592A (en) 1979-07-28
IE48147B1 (en) 1984-10-17
ATA924178A (de) 1981-06-15
EG13762A (en) 1982-09-30
NO784366L (no) 1979-06-26
FI783960A (fi) 1979-06-25

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Owner name: HOECHST AKTIENGESELLSCHAFT