ZA787209B - Cephalosporin derivatives and processes for their manufacture - Google Patents

Cephalosporin derivatives and processes for their manufacture

Info

Publication number
ZA787209B
ZA787209B ZA00787209A ZA787209A ZA787209B ZA 787209 B ZA787209 B ZA 787209B ZA 00787209 A ZA00787209 A ZA 00787209A ZA 787209 A ZA787209 A ZA 787209A ZA 787209 B ZA787209 B ZA 787209B
Authority
ZA
South Africa
Prior art keywords
manufacture
processes
cephalosporin derivatives
cephalosporin
derivatives
Prior art date
Application number
ZA00787209A
Other languages
English (en)
Inventor
J Blumbach
E Schrinner
W Duerekheimer
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA787209B publication Critical patent/ZA787209B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/44Acylated amino or imino radicals
    • C07D277/46Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA00787209A 1977-12-24 1978-12-21 Cephalosporin derivatives and processes for their manufacture ZA787209B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772758001 DE2758001A1 (de) 1977-12-24 1977-12-24 Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA787209B true ZA787209B (en) 1979-12-27

Family

ID=6027279

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00787209A ZA787209B (en) 1977-12-24 1978-12-21 Cephalosporin derivatives and processes for their manufacture

Country Status (20)

Country Link
US (1) US4293550A (xx)
EP (1) EP0002765B1 (xx)
JP (1) JPS5495592A (xx)
AT (1) AT365599B (xx)
AU (1) AU534258B2 (xx)
CA (1) CA1109461A (xx)
DE (2) DE2758001A1 (xx)
DK (1) DK578978A (xx)
EG (1) EG13762A (xx)
ES (1) ES476109A1 (xx)
FI (1) FI66007C (xx)
GR (1) GR65234B (xx)
HU (1) HU184140B (xx)
IE (1) IE48147B1 (xx)
IL (1) IL56284A (xx)
NO (1) NO784366L (xx)
NZ (1) NZ189266A (xx)
PH (1) PH15925A (xx)
PT (1) PT68964A (xx)
ZA (1) ZA787209B (xx)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
FR2466468A1 (fr) * 1979-10-02 1981-04-10 Glaxo Group Ltd Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
JPS57131794A (en) * 1980-12-31 1982-08-14 Fujisawa Pharmaceut Co Ltd Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent
US4427677A (en) * 1980-12-31 1984-01-24 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE3177090D1 (en) 1980-12-31 1989-09-28 Fujisawa Pharmaceutical Co 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
US4618606A (en) * 1982-11-17 1986-10-21 Toyama Chemical Co., Ltd. Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins
EP1059293A1 (en) * 1995-10-12 2000-12-13 Microcide Pharmaceuticals, Inc. Novel amino chlorothiazole compounds
IT1295935B1 (it) * 1997-10-30 1999-05-28 Acs Dobfar Spa Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici
TWI335332B (en) * 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
US8822727B2 (en) 2008-03-04 2014-09-02 Arena Pharmaceuticals, Inc. Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ht2c 수용체 아고니스트의 제조 방법
CN103347523A (zh) 2010-09-01 2013-10-09 艾尼纳制药公司 向具有肾损伤的个体给药氯卡色林
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
EP2611782A1 (en) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
EP3485878A1 (en) 2010-09-01 2019-05-22 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
MY181736A (en) 2012-10-09 2021-01-05 Arena Pharm Inc Method of weight management

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5168589A (xx) * 1974-12-06 1976-06-14 Shionogi Seiyaku Kk
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Also Published As

Publication number Publication date
JPS5495592A (en) 1979-07-28
IE782546L (en) 1979-06-24
EP0002765A1 (de) 1979-07-11
IE48147B1 (en) 1984-10-17
DE2861043D1 (en) 1981-11-26
CA1109461A (en) 1981-09-22
IL56284A (en) 1983-03-31
FI783960A (fi) 1979-06-25
HU184140B (en) 1984-07-30
DK578978A (da) 1979-06-25
FI66007C (fi) 1984-08-10
ATA924178A (de) 1981-06-15
JPH0132226B2 (xx) 1989-06-29
DE2758001A1 (de) 1979-07-12
ES476109A1 (es) 1979-10-16
AU534258B2 (en) 1984-01-12
PT68964A (de) 1979-01-01
EG13762A (en) 1982-09-30
NO784366L (no) 1979-06-26
AU4284878A (en) 1979-06-28
GR65234B (en) 1980-07-30
PH15925A (en) 1983-04-26
FI66007B (fi) 1984-04-30
AT365599B (de) 1982-01-25
NZ189266A (en) 1981-12-15
US4293550A (en) 1981-10-06
EP0002765B1 (de) 1981-09-02
IL56284A0 (en) 1979-03-12

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