DE2861043D1 - Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation - Google Patents

Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation

Info

Publication number
DE2861043D1
DE2861043D1 DE7878101738T DE2861043T DE2861043D1 DE 2861043 D1 DE2861043 D1 DE 2861043D1 DE 7878101738 T DE7878101738 T DE 7878101738T DE 2861043 T DE2861043 T DE 2861043T DE 2861043 D1 DE2861043 D1 DE 2861043D1
Authority
DE
Germany
Prior art keywords
preparation
pharmaceutical compositions
cephalosporin derivatives
cephalosporin
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7878101738T
Other languages
English (en)
Inventor
Jurgen Dr Blumbach
Walter Dr Durckheimer
Elmar Dr Schrinner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to DE7878101738T priority Critical patent/DE2861043D1/de
Application granted granted Critical
Publication of DE2861043D1 publication Critical patent/DE2861043D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE7878101738T 1977-12-24 1978-12-16 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation Expired DE2861043D1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE7878101738T DE2861043D1 (en) 1977-12-24 1978-12-16 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19772758001 DE2758001A1 (de) 1977-12-24 1977-12-24 Cephalosporinderivate und verfahren zu ihrer herstellung
DE7878101738T DE2861043D1 (en) 1977-12-24 1978-12-16 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation

Publications (1)

Publication Number Publication Date
DE2861043D1 true DE2861043D1 (en) 1981-11-26

Family

ID=6027279

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19772758001 Withdrawn DE2758001A1 (de) 1977-12-24 1977-12-24 Cephalosporinderivate und verfahren zu ihrer herstellung
DE7878101738T Expired DE2861043D1 (en) 1977-12-24 1978-12-16 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions and their preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE19772758001 Withdrawn DE2758001A1 (de) 1977-12-24 1977-12-24 Cephalosporinderivate und verfahren zu ihrer herstellung

Country Status (20)

Country Link
US (1) US4293550A (de)
EP (1) EP0002765B1 (de)
JP (1) JPS5495592A (de)
AT (1) AT365599B (de)
AU (1) AU534258B2 (de)
CA (1) CA1109461A (de)
DE (2) DE2758001A1 (de)
DK (1) DK578978A (de)
EG (1) EG13762A (de)
ES (1) ES476109A1 (de)
FI (1) FI66007C (de)
GR (1) GR65234B (de)
HU (1) HU184140B (de)
IE (1) IE48147B1 (de)
IL (1) IL56284A (de)
NO (1) NO784366L (de)
NZ (1) NZ189266A (de)
PH (1) PH15925A (de)
PT (1) PT68964A (de)
ZA (1) ZA787209B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703046A (en) * 1978-09-08 1987-10-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and processes for preparation thereof
FR2466468A1 (fr) * 1979-10-02 1981-04-10 Glaxo Group Ltd Nouvelles cephalosporines, leur procede de preparation et leur application en therapeutique
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4427677A (en) * 1980-12-31 1984-01-24 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE3177090D1 (en) * 1980-12-31 1989-09-28 Fujisawa Pharmaceutical Co 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
JPS57131794A (en) * 1980-12-31 1982-08-14 Fujisawa Pharmaceut Co Ltd Novel cephem compound or salt thereof, preparation of the same and preventing agent and remedy for microbism containing the same as active constituent
US4618606A (en) * 1982-11-17 1986-10-21 Toyama Chemical Co., Ltd. Antibiotic 7-(thiazolyl)-3-(pyrazinylmethyl) or (pyridazinylmethyl) cephalosporins
EP1059293A1 (de) * 1995-10-12 2000-12-13 Microcide Pharmaceuticals, Inc. Amino-chlorthiazolverbindungen
IT1295935B1 (it) * 1997-10-30 1999-05-28 Acs Dobfar Spa Derivati aminotiazolici utili nella preparazione di antibiotici b -lattamici
TWI335332B (en) * 2001-10-12 2011-01-01 Theravance Inc Cross-linked vancomycin-cephalosporin antibiotics
CN102015591B (zh) 2008-03-04 2014-01-29 艾尼纳制药公司 制备与5-ht2c激动剂(r)-8-氯-1-甲基-2，3，4，5-四氢-1h-3-苯并氮杂卓相关的中间体的方法
US9045431B2 (en) 2010-06-02 2015-06-02 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
EP2611782A1 (de) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Lorcaserin-salze mit optisch aktiven säuren
WO2012030927A2 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
EP2611449A1 (de) 2010-09-01 2013-07-10 Arena Pharmaceuticals, Inc. Verabreichung von lorcaserin an personen mit nierenerkrankungen
JP2015534563A (ja) 2012-10-09 2015-12-03 アリーナ ファーマシューティカルズ， インコーポレイテッド 体重管理の方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5168589A (de) * 1974-12-06 1976-06-14 Shionogi Seiyaku Kk
GB1536281A (en) * 1975-06-09 1978-12-20 Takeda Chemical Industries Ltd Cephem compounds
DK154939C (da) 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Also Published As

Publication number Publication date
EP0002765B1 (de) 1981-09-02
AU4284878A (en) 1979-06-28
FI66007C (fi) 1984-08-10
DK578978A (da) 1979-06-25
NZ189266A (en) 1981-12-15
PT68964A (de) 1979-01-01
PH15925A (en) 1983-04-26
IL56284A (en) 1983-03-31
AT365599B (de) 1982-01-25
JPS5495592A (en) 1979-07-28
GR65234B (en) 1980-07-30
CA1109461A (en) 1981-09-22
FI783960A (fi) 1979-06-25
FI66007B (fi) 1984-04-30
EP0002765A1 (de) 1979-07-11
IE782546L (en) 1979-06-24
ES476109A1 (es) 1979-10-16
IL56284A0 (en) 1979-03-12
IE48147B1 (en) 1984-10-17
HU184140B (en) 1984-07-30
DE2758001A1 (de) 1979-07-12
AU534258B2 (en) 1984-01-12
US4293550A (en) 1981-10-06
NO784366L (no) 1979-06-26
ATA924178A (de) 1981-06-15
ZA787209B (en) 1979-12-27
JPH0132226B2 (de) 1989-06-29
EG13762A (en) 1982-09-30

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee