FI66002C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara substituerade 9,10-dihydro-4h-tieno(3,4-b)(1,5)bensodiazepin-10-oner samt deras syraadditionssalter - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara substituerade 9,10-dihydro-4h-tieno(3,4-b)(1,5)bensodiazepin-10-oner samt deras syraadditionssalter Download PDF

Info

Publication number
FI66002C
FI66002C FI814028A FI814028A FI66002C FI 66002 C FI66002 C FI 66002C FI 814028 A FI814028 A FI 814028A FI 814028 A FI814028 A FI 814028A FI 66002 C FI66002 C FI 66002C
Authority
FI
Finland
Prior art keywords
group
thieno
dihydro
benzodiazepin
methyl
Prior art date
Application number
FI814028A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI66002B (fi
FI814028L (fi
Inventor
Volker Figala
Richard Riedel
Georg Rainer
Kurt Klemm
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of FI814028L publication Critical patent/FI814028L/fi
Publication of FI66002B publication Critical patent/FI66002B/fi
Application granted granted Critical
Publication of FI66002C publication Critical patent/FI66002C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
FI814028A 1980-05-07 1981-12-15 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara substituerade 9,10-dihydro-4h-tieno(3,4-b)(1,5)bensodiazepin-10-oner samt deras syraadditionssalter FI66002C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH358180 1980-05-07
CH358180 1980-05-07
CH65281 1981-02-02
CH65281 1981-02-02
PCT/EP1981/000042 WO1981003173A1 (en) 1980-05-07 1981-05-06 Thieno-tricyclic compounds,method for the preparation thereof,utilization of such compounds and drugs containing them
EP8100042 1981-05-06

Publications (3)

Publication Number Publication Date
FI814028L FI814028L (fi) 1981-12-15
FI66002B FI66002B (fi) 1984-04-30
FI66002C true FI66002C (fi) 1984-08-10

Family

ID=25685262

Family Applications (1)

Application Number Title Priority Date Filing Date
FI814028A FI66002C (fi) 1980-05-07 1981-12-15 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara substituerade 9,10-dihydro-4h-tieno(3,4-b)(1,5)bensodiazepin-10-oner samt deras syraadditionssalter

Country Status (21)

Country Link
EP (1) EP0039519B1 (pt)
JP (1) JPS6021994B2 (pt)
KR (1) KR850000241B1 (pt)
AT (1) ATE7299T1 (pt)
AU (1) AU538031B2 (pt)
DD (1) DD158902A5 (pt)
DE (1) DE3163361D1 (pt)
DK (1) DK157872C (pt)
ES (1) ES8205802A1 (pt)
FI (1) FI66002C (pt)
GR (1) GR82676B (pt)
HK (1) HK6890A (pt)
HU (1) HU182712B (pt)
IE (1) IE51200B1 (pt)
IL (1) IL62792A (pt)
NO (1) NO156753C (pt)
NZ (1) NZ197017A (pt)
PL (1) PL139428B1 (pt)
PT (1) PT72982B (pt)
WO (1) WO1981003173A1 (pt)
YU (1) YU42398B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3204153A1 (de) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte thienobenzodiazepinone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE3204169A1 (de) * 1982-02-06 1983-08-11 Dr. Karl Thomae Gmbh, 7950 Biberach Substituierte thienobenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3409237A1 (de) * 1984-03-14 1985-09-19 Dr. Karl Thomae Gmbh, 7950 Biberach Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3529372A1 (de) * 1985-08-16 1987-02-19 Dompe Farmaceutici Spa Aminoacyl-derivat von 4,9-dihydro-10h-pyrido(3,2-b)-thieno(3,2-e) (1,4)-diazepinon und von 4,9-dihydro-10h-pyrido(3,2-b)thieno(3,4-e) (1,4)diazepinon, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
WO1989005644A2 (fr) * 1987-12-22 1989-06-29 Byk Gulden Lomberg Chemische Fabrik Gmbh Thienotricyclene
DE3802334A1 (de) * 1988-01-27 1989-08-10 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820345A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4003322C1 (pt) * 1990-02-05 1991-06-20 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz, De

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1505795A (fr) * 1965-12-17 1967-12-15 Thomae Gmbh Dr K Procédé pour fabriquer de nouvelles 11h-pyrido[2, 3-b][1, 5]benzodiazépine-5(6h)-ones substituées en position 11
DE1931487C3 (de) * 1969-06-20 1975-12-18 Dr. Karl Thomae Gmbh, 7950 Biberach In 5-Stellung substituierte 5,10-Dihydro-11H-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11 -one und Verfahren zu ihrer Herstellung
DE1795183B1 (de) * 1968-08-20 1972-07-20 Thomae Gmbh Dr K 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate und Arzneimittel
DE1795176C3 (de) * 1968-08-20 1974-10-24 Dr. Karl Thomae Gmbh, 7950 Biberach hT-substituierte 5-Aminoacetyl-5,10-dihydro-l lH-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11one und Verfahren zu ihrer Herstellung
DE2424811C3 (de) * 1974-05-22 1981-08-20 Dr. Karl Thomae Gmbh, 7950 Biberach Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4172831A (en) * 1974-11-26 1979-10-30 Lilly Industries Limited Thieno-benzodiazepines
US4115568A (en) * 1974-11-26 1978-09-19 Lilly Industries Limited Thieno[3,2-b]-[1,5]benzodiazepines
SU629879A3 (ru) * 1974-11-26 1978-10-25 Лилли Индастриз Лимитед, (Фирма) Способ получени тиено(1,5) бензодиазепинов или их солей
US3951981A (en) * 1975-02-24 1976-04-20 American Cyanamid Company Substituted benzodiazepines and method of use
US3953430A (en) * 1975-02-24 1976-04-27 American Cyanamid Company Substituted benzodiazepin-10-ones and method of use
US4144235A (en) * 1978-03-13 1979-03-13 American Cyanamid Company Thieno[3,4-b][1,5]benzoxazepin-10-ones and thieno[3,4-b][1,5]benzothiazepin-10-ones
US4168269A (en) * 1978-04-12 1979-09-18 American Cyanamid Company Substituted thieno-benzodiazepines
US4263207A (en) * 1978-08-01 1981-04-21 Merck & Co., Inc. 10,11-Dihydrodibenzo[b,f][1,4]thiazepine carboxylic acids esters and amides thereof

Also Published As

Publication number Publication date
DE3163361D1 (en) 1984-06-07
PT72982A (en) 1981-06-01
FI66002B (fi) 1984-04-30
FI814028L (fi) 1981-12-15
PL231003A1 (pt) 1981-12-23
DK157872B (da) 1990-02-26
NO820025L (no) 1982-01-06
IL62792A (en) 1985-02-28
DK157872C (da) 1990-07-30
GR82676B (pt) 1985-02-07
AU7019881A (en) 1981-11-12
PT72982B (fr) 1982-10-21
HK6890A (en) 1990-02-02
IL62792A0 (en) 1981-07-31
NO156753C (no) 1987-11-18
IE810997L (en) 1981-11-07
YU116181A (en) 1984-02-29
HU182712B (en) 1984-03-28
NZ197017A (en) 1983-09-30
PL139428B1 (en) 1987-01-31
ES501929A0 (es) 1982-08-16
KR830006300A (ko) 1983-09-20
DD158902A5 (de) 1983-02-09
EP0039519A1 (de) 1981-11-11
DK1582A (da) 1982-01-05
EP0039519B1 (de) 1984-05-02
KR850000241B1 (ko) 1985-03-12
ATE7299T1 (de) 1984-05-15
AU538031B2 (en) 1984-07-26
WO1981003173A1 (en) 1981-11-12
JPS6021994B2 (ja) 1985-05-30
IE51200B1 (en) 1986-10-29
YU42398B (en) 1988-08-31
NO156753B (no) 1987-08-10
JPS57500695A (pt) 1982-04-22
ES8205802A1 (es) 1982-08-16

Similar Documents

Publication Publication Date Title
FI61896B (fi) Foerfarande foer framstaellning av antiinflammatoriska foer reumavaord laempliga och antitrombotiska 4-hydroxi-2h-1,2-benzodiazin-3-karboxamid-1,1-dioxider
AU616542B2 (en) Quinoline derivatives, their production and use
FI66002C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara substituerade 9,10-dihydro-4h-tieno(3,4-b)(1,5)bensodiazepin-10-oner samt deras syraadditionssalter
WO1996011929A1 (en) Biheteroaryl-carbonyl and carboxamide derivatives with 5ht 2c/2b antagonists activity
CZ410791A3 (en) Amides of thieno-triazolo-1,4-diazepino-2-carboxylic acid, process of their preparation and pharmaceutical preparation based thereon
US4216216A (en) Aromatic piperazinyl substituted dihydrouracils
NO162414B (no) Fleksibel beholder for transport og lagring av massegods.
FI68835C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-minoacyl-1,4,9,10-tetrahydropyrazolo(4,3-b)(1,5)bensodiaz epn-10-oner
US3962248A (en) Process for making 11-piperazino-diazepines, oxazepines, thiazepines and azepines
FI63582B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara 11(1-piperazinyl)-pyrazino(2,3-b)(1,5)bensoxazepiner och -b enotiazepiner
US4833136A (en) Pharmaceutically useful pyrazolo[4,3-b]pyridines
CS259516B2 (en) Method of new heterocyclic compounds production
US4591589A (en) 2-aryl pyrazolo[4,3-c]cinnolin-3-ones
FI71932B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 1,2,4-oxadiazinderivat
PL136930B1 (en) Method of obtaining novel derivatives of benzodiazepine
US4237135A (en) 2-(4-Ethyl-1-piperazinyl)-4-phenylquinoline, process for preparation thereof, and composition thereof
TAKE et al. Agents for the Treatment of Overactive Detrusor. I. Synthesis and Structure-Activity Relationships of 1, 1'-Biphenyl Derivatives
US3963740A (en) Benzo and benzothiopyranoindazole N-oxides
US4311700A (en) Pyrimidobenzodiazepinones, their use and medicaments containing them
FI63415C (fi) Foerfarande foer framstaellning av antiartritiska och antireumatiska 2,6-bis-(aminoalylamino)-benzo-(1,2-d:5,4-d')-bistiazoler och 2-amino-6-(aminoacylamino)-benzo-(1,2-d:5,4-d')-bistiazoler
US4026899A (en) Benzo and benzothiopyranoindazole N-oxides
US4324786A (en) Pyrido[2,3-e]-as-triazine derivatives and pharmaceutical compositions
Hegab et al. Synthesis and pharmacological activities of some condensed 4-chloro-2, 2-dialkyl chromene-3-carbaldehyde derivatives
US3555012A (en) Dibenzothiadiazocine derivatives
NZ230355A (en) 4-substituted piperidinoalkyl (iso) oxindole derivatives

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BYK GULDEN LOMBERG CHEMISCHE FABRIK