FI64374C - Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner Download PDF

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Publication number
FI64374C
FI64374C FI780023A FI780023A FI64374C FI 64374 C FI64374 C FI 64374C FI 780023 A FI780023 A FI 780023A FI 780023 A FI780023 A FI 780023A FI 64374 C FI64374 C FI 64374C
Authority
FI
Finland
Prior art keywords
phenyl
carbon atoms
compounds
alkyl
compound
Prior art date
Application number
FI780023A
Other languages
English (en)
Finnish (fi)
Other versions
FI780023A (fi
FI64374B (fi
Inventor
Jr Paul L Warner
Jr Edward J Luber
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI780023A publication Critical patent/FI780023A/fi
Priority to FI821308A priority Critical patent/FI64375C/fi
Application granted granted Critical
Publication of FI64374B publication Critical patent/FI64374B/fi
Publication of FI64374C publication Critical patent/FI64374C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI780023A 1977-01-07 1978-01-04 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner FI64374C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI821308A FI64375C (fi) 1977-01-07 1982-04-14 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75764077A 1977-01-07 1977-01-07
US75764077 1977-01-07

Publications (3)

Publication Number Publication Date
FI780023A FI780023A (fi) 1978-07-08
FI64374B FI64374B (fi) 1983-07-29
FI64374C true FI64374C (fi) 1983-11-10

Family

ID=25048641

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780023A FI64374C (fi) 1977-01-07 1978-01-04 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner

Country Status (19)

Country Link
US (1) US4160097A (ko)
JP (2) JPS5387398A (ko)
AU (1) AU521807B2 (ko)
BE (1) BE862608A (ko)
CA (1) CA1149385A (ko)
CH (2) CH636102A5 (ko)
CS (1) CS200232B2 (ko)
DE (2) DE2858766C2 (ko)
DK (1) DK157024C (ko)
FI (1) FI64374C (ko)
FR (1) FR2376858A1 (ko)
GB (2) GB1579498A (ko)
GR (1) GR73168B (ko)
IE (1) IE46191B1 (ko)
LU (1) LU78813A1 (ko)
NL (1) NL7800114A (ko)
SE (2) SE436359B (ko)
YU (1) YU44663B (ko)
ZA (1) ZA7827B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE439308B (sv) * 1978-08-02 1985-06-10 Roussel Uclaf Imidazo(1,2-a)kinoxaliner och farmaceutiska kompositioner derav
JPS5569567A (en) * 1978-11-21 1980-05-26 Eisai Co Ltd Novel imidazole compound, and antidepressant containing the same
IT1209431B (it) * 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.
DE3830054A1 (de) * 1988-09-03 1990-03-15 Boehringer Mannheim Gmbh Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
JPH0349309U (ko) * 1989-09-21 1991-05-14
US6235740B1 (en) 1997-08-25 2001-05-22 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
US6635626B1 (en) 1997-08-25 2003-10-21 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
WO1999024434A1 (en) 1997-11-11 1999-05-20 Ono Pharmaceutical Co., Ltd. Fused pyrazine compounds
WO1999045009A1 (en) * 1998-03-04 1999-09-10 Bristol-Myers Squibb Company Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
US6869956B2 (en) * 2000-10-03 2005-03-22 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
US6960585B2 (en) 2000-10-03 2005-11-01 Bristol-Myers Squibb Company Amino-substituted tetracyclic compounds useful as anti-inflammatory agents and pharmaceutical compositions comprising same
CZ20032287A3 (cs) * 2001-02-01 2004-02-18 Bristol-Myers Squibb Company Způsoby léčení zánětlivých a imunitních nemocí za použití inhibitorů IkB kinázy (IKK)
EP2066642A1 (en) * 2006-09-25 2009-06-10 Arete Therapeutics, INC. Soluble epoxide hydrolase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541109A (en) * 1968-06-25 1970-11-17 Du Pont 1-substituted imidazoles useful in acth reserve assay
US4011236A (en) * 1968-09-09 1977-03-08 Merck & Co., Inc. N-(benzimidazol-2-yl)arylcarboxamides as ultraviolet (uv) light absorbers
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
US3994893A (en) * 1975-11-03 1976-11-30 E. R. Squibb & Sons, Inc. 4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic acid and esters

Also Published As

Publication number Publication date
DE2858766C2 (ko) 1990-04-05
CH636102A5 (fr) 1983-05-13
BE862608A (fr) 1978-07-03
DE2800480C2 (ko) 1990-04-12
JPS6259110B2 (ko) 1987-12-09
SE436359B (sv) 1984-12-03
US4160097A (en) 1979-07-03
FR2376858A1 (fr) 1978-08-04
DK157024C (da) 1990-04-02
SE7800138L (sv) 1978-07-08
DK4278A (da) 1978-07-08
SE8300945D0 (sv) 1983-02-21
CS200232B2 (en) 1980-08-29
CH640229A5 (fr) 1983-12-30
YU44663B (en) 1990-12-31
GB1579499A (en) 1980-11-19
SE8300945L (sv) 1983-02-21
JPH0130825B2 (ko) 1989-06-22
CA1149385A (en) 1983-07-05
JPS61171470A (ja) 1986-08-02
GR73168B (ko) 1984-02-14
IE780037L (en) 1978-07-07
AU521807B2 (en) 1982-04-29
ZA7827B (en) 1979-01-31
YU2178A (en) 1990-04-30
DE2800480A1 (de) 1978-07-13
IE46191B1 (en) 1983-03-23
FI780023A (fi) 1978-07-08
LU78813A1 (fr) 1978-09-18
GB1579498A (en) 1980-11-19
JPS5387398A (en) 1978-08-01
AU3233178A (en) 1979-07-19
DK157024B (da) 1989-10-30
NL7800114A (nl) 1978-07-11
FI64374B (fi) 1983-07-29
FR2376858B1 (ko) 1980-10-24
SE460477B (sv) 1989-10-16

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Owner name: BRISTOL-MYERS CO