DK4278A - 4-substituerede imidazo(1,2-a)quinoxaliner og mellemproduktersamt fremgangsmaade til fremstilling deraf - Google Patents

4-substituerede imidazo(1,2-a)quinoxaliner og mellemproduktersamt fremgangsmaade til fremstilling deraf

Info

Publication number
DK4278A
DK4278A DK4278A DK4278A DK4278A DK 4278 A DK4278 A DK 4278A DK 4278 A DK4278 A DK 4278A DK 4278 A DK4278 A DK 4278A DK 4278 A DK4278 A DK 4278A
Authority
DK
Denmark
Prior art keywords
quinoxalines
manufacture
substituted imidazo
intermediate procedures
procedures
Prior art date
Application number
DK4278A
Other languages
English (en)
Other versions
DK157024B (da
DK157024C (da
Inventor
Jr P L Warner
Jr E J Luber
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK4278A publication Critical patent/DK4278A/da
Publication of DK157024B publication Critical patent/DK157024B/da
Application granted granted Critical
Publication of DK157024C publication Critical patent/DK157024C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK004278A 1977-01-07 1978-01-04 Analogifremgangsmaade til fremstilling af 4-substituerede imidazooe1,2-aaaquinoxaliner samt 1-(2-acylaminophenyl)imidazoler til anvendelse som udgangsmaterialer ved fremgangsmaaden DK157024C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75764077A 1977-01-07 1977-01-07
US75764077 1977-01-07

Publications (3)

Publication Number Publication Date
DK4278A true DK4278A (da) 1978-07-08
DK157024B DK157024B (da) 1989-10-30
DK157024C DK157024C (da) 1990-04-02

Family

ID=25048641

Family Applications (1)

Application Number Title Priority Date Filing Date
DK004278A DK157024C (da) 1977-01-07 1978-01-04 Analogifremgangsmaade til fremstilling af 4-substituerede imidazooe1,2-aaaquinoxaliner samt 1-(2-acylaminophenyl)imidazoler til anvendelse som udgangsmaterialer ved fremgangsmaaden

Country Status (19)

Country Link
US (1) US4160097A (da)
JP (2) JPS5387398A (da)
AU (1) AU521807B2 (da)
BE (1) BE862608A (da)
CA (1) CA1149385A (da)
CH (2) CH636102A5 (da)
CS (1) CS200232B2 (da)
DE (2) DE2858766C2 (da)
DK (1) DK157024C (da)
FI (1) FI64374C (da)
FR (1) FR2376858A1 (da)
GB (2) GB1579498A (da)
GR (1) GR73168B (da)
IE (1) IE46191B1 (da)
LU (1) LU78813A1 (da)
NL (1) NL7800114A (da)
SE (2) SE436359B (da)
YU (1) YU44663B (da)
ZA (1) ZA7827B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE439308B (sv) * 1978-08-02 1985-06-10 Roussel Uclaf Imidazo(1,2-a)kinoxaliner och farmaceutiska kompositioner derav
JPS5569567A (en) * 1978-11-21 1980-05-26 Eisai Co Ltd Novel imidazole compound, and antidepressant containing the same
IT1209431B (it) * 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.
DE3830054A1 (de) * 1988-09-03 1990-03-15 Boehringer Mannheim Gmbh Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
JPH0349309U (da) * 1989-09-21 1991-05-14
US6235740B1 (en) 1997-08-25 2001-05-22 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
US6635626B1 (en) 1997-08-25 2003-10-21 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
BR9814628A (pt) 1997-11-11 2001-11-27 Ono Pharmaceutical Co Derivados de pirazina fundidos
EP1066286B1 (en) * 1998-03-04 2009-04-29 Bristol-Myers Squibb Company Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
US6869956B2 (en) * 2000-10-03 2005-03-22 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
JP5021148B2 (ja) 2000-10-03 2012-09-05 ブリストル−マイヤーズ スクイブ カンパニー 抗炎症薬として有用なアミノ置換４環化合物および該化合物を含有する医薬組成物
JP2004529088A (ja) * 2001-02-01 2004-09-24 ブリストル−マイヤーズ　スクイブ　カンパニー ＩｋＢキナーゼ（ＩＫＫ）のインヒビターを用いる炎症性および免疫疾患の処置法
EP2066642A1 (en) * 2006-09-25 2009-06-10 Arete Therapeutics, INC. Soluble epoxide hydrolase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541109A (en) * 1968-06-25 1970-11-17 Du Pont 1-substituted imidazoles useful in acth reserve assay
US4011236A (en) * 1968-09-09 1977-03-08 Merck & Co., Inc. N-(benzimidazol-2-yl)arylcarboxamides as ultraviolet (uv) light absorbers
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
US3994893A (en) * 1975-11-03 1976-11-30 E. R. Squibb & Sons, Inc. 4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic acid and esters

Also Published As

Publication number Publication date
DE2800480C2 (da) 1990-04-12
JPS5387398A (en) 1978-08-01
YU2178A (en) 1990-04-30
GB1579499A (en) 1980-11-19
FI780023A (fi) 1978-07-08
LU78813A1 (fr) 1978-09-18
YU44663B (en) 1990-12-31
FI64374C (fi) 1983-11-10
US4160097A (en) 1979-07-03
DK157024B (da) 1989-10-30
FI64374B (fi) 1983-07-29
FR2376858B1 (da) 1980-10-24
IE780037L (en) 1978-07-07
GR73168B (da) 1984-02-14
DK157024C (da) 1990-04-02
SE460477B (sv) 1989-10-16
JPS61171470A (ja) 1986-08-02
SE7800138L (sv) 1978-07-08
CA1149385A (en) 1983-07-05
SE8300945D0 (sv) 1983-02-21
DE2800480A1 (de) 1978-07-13
SE436359B (sv) 1984-12-03
ZA7827B (en) 1979-01-31
JPS6259110B2 (da) 1987-12-09
IE46191B1 (en) 1983-03-23
DE2858766C2 (da) 1990-04-05
AU521807B2 (en) 1982-04-29
JPH0130825B2 (da) 1989-06-22
CH636102A5 (fr) 1983-05-13
CH640229A5 (fr) 1983-12-30
CS200232B2 (en) 1980-08-29
FR2376858A1 (fr) 1978-08-04
NL7800114A (nl) 1978-07-11
BE862608A (fr) 1978-07-03
AU3233178A (en) 1979-07-19
GB1579498A (en) 1980-11-19
SE8300945L (sv) 1983-02-21

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