FI780023A - 4-substituerade imidazo 1 2-a kinoxaliner och intermediater samt foerfarande foer framstaellning av dessa - Google Patents

4-substituerade imidazo 1 2-a kinoxaliner och intermediater samt foerfarande foer framstaellning av dessa

Info

Publication number
FI780023A
FI780023A FI780023A FI780023A FI780023A FI 780023 A FI780023 A FI 780023A FI 780023 A FI780023 A FI 780023A FI 780023 A FI780023 A FI 780023A FI 780023 A FI780023 A FI 780023A
Authority
FI
Finland
Prior art keywords
kinoxaliner
intermediater
dessa
imidazo
och
Prior art date
Application number
FI780023A
Other languages
English (en)
Other versions
FI64374B (fi
FI64374C (fi
Inventor
Jr Paul L Warner
Jr Edward J Luber
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI780023A publication Critical patent/FI780023A/fi
Priority to FI821308A priority Critical patent/FI64375C/fi
Publication of FI64374B publication Critical patent/FI64374B/fi
Application granted granted Critical
Publication of FI64374C publication Critical patent/FI64374C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI780023A 1977-01-07 1978-01-04 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner FI64374C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI821308A FI64375C (fi) 1977-01-07 1982-04-14 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75764077A 1977-01-07 1977-01-07
US75764077 1977-01-07

Publications (3)

Publication Number Publication Date
FI780023A true FI780023A (fi) 1978-07-08
FI64374B FI64374B (fi) 1983-07-29
FI64374C FI64374C (fi) 1983-11-10

Family

ID=25048641

Family Applications (1)

Application Number Title Priority Date Filing Date
FI780023A FI64374C (fi) 1977-01-07 1978-01-04 Foerfarande foer framstaellning av terapeutiskt anvaendbara 4-ubstituerade imidazo(1,2-a)kinoxaliner

Country Status (19)

Country Link
US (1) US4160097A (fi)
JP (2) JPS5387398A (fi)
AU (1) AU521807B2 (fi)
BE (1) BE862608A (fi)
CA (1) CA1149385A (fi)
CH (2) CH636102A5 (fi)
CS (1) CS200232B2 (fi)
DE (2) DE2858766C2 (fi)
DK (1) DK157024C (fi)
FI (1) FI64374C (fi)
FR (1) FR2376858A1 (fi)
GB (2) GB1579499A (fi)
GR (1) GR73168B (fi)
IE (1) IE46191B1 (fi)
LU (1) LU78813A1 (fi)
NL (1) NL7800114A (fi)
SE (2) SE436359B (fi)
YU (1) YU44663B (fi)
ZA (1) ZA7827B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE439308B (sv) * 1978-08-02 1985-06-10 Roussel Uclaf Imidazo(1,2-a)kinoxaliner och farmaceutiska kompositioner derav
JPS5569567A (en) * 1978-11-21 1980-05-26 Eisai Co Ltd Novel imidazole compound, and antidepressant containing the same
IT1209431B (it) * 1980-11-28 1989-07-16 Angeli Inst Spa Imidazolilfenil amidine, processi per la loro preparazione e loro impiego farmaceutico, ed intermedi di preparazione.
DE3830054A1 (de) * 1988-09-03 1990-03-15 Boehringer Mannheim Gmbh Phenylamide - verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel
JPH0349309U (fi) * 1989-09-21 1991-05-14
US6235740B1 (en) 1997-08-25 2001-05-22 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
US6635626B1 (en) 1997-08-25 2003-10-21 Bristol-Myers Squibb Co. Imidazoquinoxaline protein tyrosine kinase inhibitors
CN1285834A (zh) 1997-11-11 2001-02-28 小野药品工业株式会社 稠合吡嗪化合物
DE69940808D1 (de) * 1998-03-04 2009-06-10 Bristol Myers Squibb Co Heterocyclen substituierte imidazopyrazine als protein- tyrosin-kinase-inhibitoren
US6869956B2 (en) * 2000-10-03 2005-03-22 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of IκB kinase (IKK)
DE60117835T2 (de) 2000-10-03 2006-10-19 Bristol-Myers Squibb Co. Amino- substituierte tetracyclische Verbindungen,die als entzündungshemmende Mittel nützlich sind, und diese enthaltende Arzneimittel
CA2436770A1 (en) * 2001-02-01 2002-08-08 James R. Burke Methods of treating inflammatory and immune diseases using inhibitors of ikb kinase (ikk)
EP2066642A1 (en) * 2006-09-25 2009-06-10 Arete Therapeutics, INC. Soluble epoxide hydrolase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3541109A (en) * 1968-06-25 1970-11-17 Du Pont 1-substituted imidazoles useful in acth reserve assay
US4011236A (en) * 1968-09-09 1977-03-08 Merck & Co., Inc. N-(benzimidazol-2-yl)arylcarboxamides as ultraviolet (uv) light absorbers
GB1347493A (en) * 1971-02-11 1974-02-27 Aspro Nicholas Ltd Benzazine derivatives
US3994893A (en) * 1975-11-03 1976-11-30 E. R. Squibb & Sons, Inc. 4-Amino derivatives of pyrozolo[1,5-a]quinoxaline-3-carboxylic acid and esters

Also Published As

Publication number Publication date
FI64374B (fi) 1983-07-29
FR2376858B1 (fi) 1980-10-24
FI64374C (fi) 1983-11-10
CA1149385A (en) 1983-07-05
JPS5387398A (en) 1978-08-01
DK157024B (da) 1989-10-30
DK4278A (da) 1978-07-08
SE7800138L (sv) 1978-07-08
JPH0130825B2 (fi) 1989-06-22
JPS61171470A (ja) 1986-08-02
FR2376858A1 (fr) 1978-08-04
JPS6259110B2 (fi) 1987-12-09
DK157024C (da) 1990-04-02
ZA7827B (en) 1979-01-31
SE436359B (sv) 1984-12-03
LU78813A1 (fr) 1978-09-18
DE2858766C2 (fi) 1990-04-05
SE8300945D0 (sv) 1983-02-21
GB1579498A (en) 1980-11-19
AU3233178A (en) 1979-07-19
CS200232B2 (en) 1980-08-29
IE46191B1 (en) 1983-03-23
NL7800114A (nl) 1978-07-11
BE862608A (fr) 1978-07-03
SE8300945L (sv) 1983-02-21
CH636102A5 (fr) 1983-05-13
AU521807B2 (en) 1982-04-29
US4160097A (en) 1979-07-03
YU2178A (en) 1990-04-30
CH640229A5 (fr) 1983-12-30
GB1579499A (en) 1980-11-19
SE460477B (sv) 1989-10-16
DE2800480A1 (de) 1978-07-13
IE780037L (en) 1978-07-07
GR73168B (fi) 1984-02-14
YU44663B (en) 1990-12-31
DE2800480C2 (fi) 1990-04-12

Similar Documents

Publication Publication Date Title
FI792000A (fi) Plastbag med flera vaeggar samt foerfarande och anordning foer framstaellande av densamma
FI802177A (fi) Cylinderlaos nyckel foer laoset samt foerfarande foer framstaellning av nyckeln
FI802178A (fi) Cylinderlaos-nyckel-kombination nyckel foer laoset samt foerfarande foer framstaellning av nyckeln
FI65331B (fi) Reglerings- och maetningssystem foer uppvaermning/avkylning lagenhetsvis samt foerfarande foer kalibrering av systemet
FI780128A (fi) Foerfarande foer oeverdragning av glasfibrer samt vattenhaltig blandning foer utfoerande av foerfarandet
FI782550A (fi) Daeck samt kombination av daeck och hjul
FI802652A (fi) Salter av (+)-katekin deras framstaellning och anvaendning samt dessa salter innehaollande blandningar
FI780429A (fi) Inflammationsmotverkande imidazoler samt deras motsvarande sulfoxider och sulfoner
FI783370A (fi) Foer byggnader avsedd takbeklaednad samt foerfarande och anordning foer tillverkning av takbeklaednaden
FI792173A (fi) Flaetad packning samt foerfarande och anordning foer framstaellning av packningen
FI781728A (fi) Kristallina alkalimetallalumosilikater samt foerfarande foer framstaellning av desamma
FI780023A (fi) 4-substituerade imidazo 1 2-a kinoxaliner och intermediater samt foerfarande foer framstaellning av dessa
FI782066A (fi) Foerfarande foer kondensering av aonga samt ytkondensor foer utfoerande av foerfarandet
FI782556A (fi) Plastroerfoerband samt foerfarande och anordning foer tillverkning av foerfarandet
FI821035A0 (fi) Imidazo/1,2-a/pyrimidinderivat, deras framstaellning och anvaendning vid sjukvaord
FI802332A (fi) N-glykocylderivat av antracyklina antibioter samt deras framstaellningsfoerfarande
FI781199A (fi) Bindemedel foer framstaellning av vattenblandningar foer oeverdragning av tryckpapper och -kartong samt foerfarande foer framstaellning av naemnda bindemedel
FI55293C (fi) Foerfarande samt i armleden och i fickan anvaendbar anordning foer kontuerlig uppmaetning av hjaertpulsen och pulsens aoterstaellning
FI783246A (fi) Belaeggningsmassa och daerav framstaellt tryckkaensligt genomslagsmaterial foerfarande foer framstaellning av genomslagsmaterialet samt genomslagssats daerav
FI790022A (fi) Anordning foer maetning av kyleffektbehovet foer kylt utrymme samt av kylmaskineriets kyleffekt
FI780233A (fi) Exploderande stubintraod samt tillverkningsfoerfarande och anordning foer detsamma
FI780428A (fi) Inflammationsmotverkande imidazoler samt deras motsvarande sulfoxider och sulfoner
FI780224A (fi) Gaengformande skruv samt foerfarande foer framstaellning av denna och valsback foer genomfoerande av foerfarandet
FI791674A (fi) Foerfarande och anordning foer framstaellning av en metallkapsell samt foerbaettrad metallkapsel
FI803280L (fi) Kombination av daeck och faelg samt daeck foer kombinationen

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: BRISTOL-MYERS CO