FI59244C - Foerfarande foer framstaellning av farmaceutiskt anvaendbara karbazoler - Google Patents

Foerfarande foer framstaellning av farmaceutiskt anvaendbara karbazoler Download PDF

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Publication number
FI59244C
FI59244C FI2311/73A FI231173A FI59244C FI 59244 C FI59244 C FI 59244C FI 2311/73 A FI2311/73 A FI 2311/73A FI 231173 A FI231173 A FI 231173A FI 59244 C FI59244 C FI 59244C
Authority
FI
Finland
Prior art keywords
acetic acid
formula
group
chloro
ethyl ester
Prior art date
Application number
FI2311/73A
Other languages
English (en)
Finnish (fi)
Other versions
FI59244B (fi
Inventor
Leo Berger
Alfred John Corraz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of FI59244B publication Critical patent/FI59244B/fi
Publication of FI59244C publication Critical patent/FI59244C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/86Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI2311/73A 1972-07-24 1973-07-23 Foerfarande foer framstaellning av farmaceutiskt anvaendbara karbazoler FI59244C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27414272A 1972-07-24 1972-07-24
US27414272 1972-07-24

Publications (2)

Publication Number Publication Date
FI59244B FI59244B (fi) 1981-03-31
FI59244C true FI59244C (fi) 1981-07-10

Family

ID=23046965

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2311/73A FI59244C (fi) 1972-07-24 1973-07-23 Foerfarande foer framstaellning av farmaceutiskt anvaendbara karbazoler

Country Status (26)

Country Link
JP (1) JPS5740144B2 (hu)
KR (1) KR780000289B1 (hu)
AR (1) AR205331A1 (hu)
AT (1) AT325607B (hu)
AU (1) AU475534B2 (hu)
BE (1) BE802596A (hu)
CA (1) CA1026348A (hu)
CH (1) CH587819A5 (hu)
DD (1) DD107681A5 (hu)
DE (1) DE2337340C2 (hu)
DK (1) DK138537B (hu)
FI (1) FI59244C (hu)
FR (1) FR2193611B1 (hu)
GB (1) GB1385620A (hu)
HK (1) HK49878A (hu)
HU (1) HU167611B (hu)
IE (1) IE37942B1 (hu)
IL (1) IL42799A (hu)
KE (1) KE2847A (hu)
LU (1) LU68071A1 (hu)
MY (1) MY7800315A (hu)
NL (1) NL169877C (hu)
NO (1) NO142865C (hu)
SE (2) SE402283B (hu)
SU (1) SU509220A3 (hu)
ZA (1) ZA734047B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146542A (en) * 1978-06-12 1979-03-27 Hoffmann-La Roche Inc. Dihydrocarbazole acetic acid and esters thereof
US4150031A (en) * 1978-06-26 1979-04-17 Hoffmann-La Roche Inc. Hydroxy methyl carbazole acetic acid and esters
US4158007A (en) * 1978-08-21 1979-06-12 Hoffmann-La Roche Inc. Carbazole methyl malonates
US4501908A (en) * 1981-03-12 1985-02-26 Hoffmann-La Roche Inc. 2,3-Isopropylidene ribonic acid, 1,4-lactones
JPS6040256U (ja) * 1983-08-25 1985-03-20 伊東 璋 容器類洗浄機
EP0234708B1 (en) * 1986-01-23 1991-02-27 Merck Frosst Canada Inc. Tetrahydrocarbazole 1-alkanoic acids
EP0239306B1 (en) 1986-03-27 1993-06-02 Merck Frosst Canada Inc. Tetrahydrocarbazole esters
CA1326030C (en) * 1987-07-21 1994-01-11 John W. Gillard Cyclohept[b]indolealkanoic acids
EP0307077A1 (en) * 1987-07-21 1989-03-15 Merck Frosst Canada Inc. Tetrahydrocarbazoles for the improvement of cyclosporin therapy
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
JP2004010601A (ja) * 2002-06-11 2004-01-15 Nippon Steel Chem Co Ltd インドール誘導体の製造方法及びそのための有用な中間体
US7332516B2 (en) 2003-01-14 2008-02-19 Merck + Co., Inc. Geminally di-substituted NSAID derivatives as Aβ42 lowering agents
MXPA05011850A (es) * 2003-05-06 2006-05-25 Air Prod & Chem Almacen de hidrogeno reversible hidrogenado de los sustratros pi-conjugados.
WO2005016882A1 (en) * 2003-08-15 2005-02-24 Universite Laval Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbazoles
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
SI2802320T1 (sl) * 2011-11-15 2019-08-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd., Triciklične spojine, sestavki, ki jih obsegajo in njihove uporabe
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
CN114787130A (zh) * 2020-03-25 2022-07-22 捷恩智株式会社 化合物、液晶组合物及液晶显示元件

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (hu) *
US3580926A (en) * 1969-11-10 1971-05-25 Parke Davis & Co Carbazole-4-alkanoic acids and tetrahydrocarbazole-4-alkanoic acids
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Also Published As

Publication number Publication date
CH587819A5 (hu) 1977-05-13
DK138537C (hu) 1979-03-05
NO142865C (no) 1980-11-05
SU509220A3 (ru) 1976-03-30
NL169877C (nl) 1982-09-01
AU5839073A (en) 1975-01-23
NO142865B (no) 1980-07-28
LU68071A1 (hu) 1975-04-11
FR2193611A1 (hu) 1974-02-22
DE2337340C2 (de) 1985-05-02
AT325607B (de) 1975-10-27
NL169877B (nl) 1982-04-01
SE7605813L (sv) 1976-05-21
ZA734047B (en) 1974-03-27
HK49878A (en) 1978-09-08
KR780000289B1 (en) 1978-08-10
CA1026348A (en) 1978-02-14
FR2193611B1 (hu) 1976-05-14
IE37942L (en) 1974-01-24
HU167611B (hu) 1975-11-28
MY7800315A (en) 1978-12-31
DK138537B (da) 1978-09-25
GB1385620A (en) 1975-02-26
JPS5740144B2 (hu) 1982-08-25
ATA649773A (de) 1975-01-15
NL7310275A (hu) 1974-01-28
IL42799A (en) 1977-03-31
IL42799A0 (en) 1973-10-25
DD107681A5 (hu) 1974-08-12
SE402283B (sv) 1978-06-26
DE2337340A1 (de) 1974-02-14
FI59244B (fi) 1981-03-31
BE802596A (fr) 1974-01-21
KE2847A (en) 1978-06-30
AU475534B2 (en) 1976-08-26
IE37942B1 (en) 1977-11-23
AR205331A1 (es) 1976-04-30
JPS4943973A (hu) 1974-04-25

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