NO142865C - Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karbazoler - Google Patents

Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karbazoler

Info

Publication number
NO142865C
NO142865C NO2975/73A NO297573A NO142865C NO 142865 C NO142865 C NO 142865C NO 2975/73 A NO2975/73 A NO 2975/73A NO 297573 A NO297573 A NO 297573A NO 142865 C NO142865 C NO 142865C
Authority
NO
Norway
Prior art keywords
carbzols
preparation
new therapeutic
therapeutic active
analogy procedure
Prior art date
Application number
NO2975/73A
Other languages
English (en)
Other versions
NO142865B (no
Inventor
Leo Berger
Alfred John Corraz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO142865B publication Critical patent/NO142865B/no
Publication of NO142865C publication Critical patent/NO142865C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/86Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO2975/73A 1972-07-24 1973-07-23 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karbazoler NO142865C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27414272A 1972-07-24 1972-07-24

Publications (2)

Publication Number Publication Date
NO142865B NO142865B (no) 1980-07-28
NO142865C true NO142865C (no) 1980-11-05

Family

ID=23046965

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2975/73A NO142865C (no) 1972-07-24 1973-07-23 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karbazoler

Country Status (26)

Country Link
JP (1) JPS5740144B2 (no)
KR (1) KR780000289B1 (no)
AR (1) AR205331A1 (no)
AT (1) AT325607B (no)
AU (1) AU475534B2 (no)
BE (1) BE802596A (no)
CA (1) CA1026348A (no)
CH (1) CH587819A5 (no)
DD (1) DD107681A5 (no)
DE (1) DE2337340C2 (no)
DK (1) DK138537B (no)
FI (1) FI59244C (no)
FR (1) FR2193611B1 (no)
GB (1) GB1385620A (no)
HK (1) HK49878A (no)
HU (1) HU167611B (no)
IE (1) IE37942B1 (no)
IL (1) IL42799A (no)
KE (1) KE2847A (no)
LU (1) LU68071A1 (no)
MY (1) MY7800315A (no)
NL (1) NL169877C (no)
NO (1) NO142865C (no)
SE (2) SE402283B (no)
SU (1) SU509220A3 (no)
ZA (1) ZA734047B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146542A (en) * 1978-06-12 1979-03-27 Hoffmann-La Roche Inc. Dihydrocarbazole acetic acid and esters thereof
US4150031A (en) * 1978-06-26 1979-04-17 Hoffmann-La Roche Inc. Hydroxy methyl carbazole acetic acid and esters
US4158007A (en) * 1978-08-21 1979-06-12 Hoffmann-La Roche Inc. Carbazole methyl malonates
US4501908A (en) * 1981-03-12 1985-02-26 Hoffmann-La Roche Inc. 2,3-Isopropylidene ribonic acid, 1,4-lactones
JPS6040256U (ja) * 1983-08-25 1985-03-20 伊東 璋 容器類洗浄機
DE3768097D1 (de) * 1986-01-23 1991-04-04 Merck Frosst Canada Inc Tetrahydrocarbazol-1-alkansaeuren.
ATE90076T1 (de) 1986-03-27 1993-06-15 Merck Frosst Canada Inc Tetrahydrocarbazole ester.
CA1326030C (en) * 1987-07-21 1994-01-11 John W. Gillard Cyclohept[b]indolealkanoic acids
EP0307077A1 (en) * 1987-07-21 1989-03-15 Merck Frosst Canada Inc. Tetrahydrocarbazoles for the improvement of cyclosporin therapy
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
JP2004010601A (ja) * 2002-06-11 2004-01-15 Nippon Steel Chem Co Ltd インドール誘導体の製造方法及びそのための有用な中間体
WO2004064771A2 (en) 2003-01-14 2004-08-05 Merck & Co., Inc. Geminally di-substituted nsaid derivatives as abeta 42 lowering agents
MXPA05011850A (es) * 2003-05-06 2006-05-25 Air Prod & Chem Almacen de hidrogeno reversible hidrogenado de los sustratros pi-conjugados.
JP2007502251A (ja) * 2003-08-15 2007-02-08 ユニヴェルシテ・ラヴァル 2位官能化及び2,7位二官能化カルバゾール類のモノマー類、オリゴマー類、及びポリマー類
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
PT2802320T (pt) * 2011-11-15 2019-06-17 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Compostos tricíclicos, composições que os compreendem e usos destas
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
WO2021193708A1 (ja) * 2020-03-25 2021-09-30 Jnc株式会社 化合物、液晶組成物および液晶表示素子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (no) *
US3580926A (en) * 1969-11-10 1971-05-25 Parke Davis & Co Carbazole-4-alkanoic acids and tetrahydrocarbazole-4-alkanoic acids
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Also Published As

Publication number Publication date
IE37942B1 (en) 1977-11-23
DE2337340A1 (de) 1974-02-14
LU68071A1 (no) 1975-04-11
FR2193611A1 (no) 1974-02-22
SE7605813L (sv) 1976-05-21
FR2193611B1 (no) 1976-05-14
ZA734047B (en) 1974-03-27
KE2847A (en) 1978-06-30
FI59244C (fi) 1981-07-10
GB1385620A (en) 1975-02-26
CH587819A5 (no) 1977-05-13
IL42799A0 (en) 1973-10-25
HU167611B (no) 1975-11-28
DE2337340C2 (de) 1985-05-02
JPS5740144B2 (no) 1982-08-25
DK138537B (da) 1978-09-25
SU509220A3 (ru) 1976-03-30
AU5839073A (en) 1975-01-23
IL42799A (en) 1977-03-31
FI59244B (fi) 1981-03-31
MY7800315A (en) 1978-12-31
NL7310275A (no) 1974-01-28
AR205331A1 (es) 1976-04-30
CA1026348A (en) 1978-02-14
AU475534B2 (en) 1976-08-26
NL169877B (nl) 1982-04-01
HK49878A (en) 1978-09-08
KR780000289B1 (en) 1978-08-10
IE37942L (en) 1974-01-24
DK138537C (no) 1979-03-05
NO142865B (no) 1980-07-28
ATA649773A (de) 1975-01-15
DD107681A5 (no) 1974-08-12
BE802596A (fr) 1974-01-21
NL169877C (nl) 1982-09-01
SE402283B (sv) 1978-06-26
AT325607B (de) 1975-10-27
JPS4943973A (no) 1974-04-25

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