FI58135C - Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat Download PDF

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Publication number
FI58135C
FI58135C FI773814A FI773814A FI58135C FI 58135 C FI58135 C FI 58135C FI 773814 A FI773814 A FI 773814A FI 773814 A FI773814 A FI 773814A FI 58135 C FI58135 C FI 58135C
Authority
FI
Finland
Prior art keywords
group
alkyl
substituted
formula
hellebrigenin
Prior art date
Application number
FI773814A
Other languages
English (en)
Finnish (fi)
Other versions
FI58135B (fi
FI773814A (fi
Inventor
Otto Isaac
Klaus Posselt
Horst Uthemann
Klaus Thiemer
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of FI773814A publication Critical patent/FI773814A/fi
Publication of FI58135B publication Critical patent/FI58135B/fi
Application granted granted Critical
Publication of FI58135C publication Critical patent/FI58135C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J43/00Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J19/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI773814A 1976-12-17 1977-12-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat FI58135C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB5275976 1976-12-17
GB52759/76A GB1577633A (en) 1976-12-17 1976-12-17 Acyl derivatives of hellebrigenin

Publications (3)

Publication Number Publication Date
FI773814A FI773814A (fi) 1978-06-18
FI58135B FI58135B (fi) 1980-08-29
FI58135C true FI58135C (fi) 1980-12-10

Family

ID=10465185

Family Applications (1)

Application Number Title Priority Date Filing Date
FI773814A FI58135C (fi) 1976-12-17 1977-12-16 Foerfarande foer framstaellning av terapeutiskt anvaendbara hellebrigeninacylderivat

Country Status (15)

Country Link
JP (1) JPS591279B2 (hu)
AT (1) AT372391B (hu)
BE (1) BE861968A (hu)
CH (1) CH639107A5 (hu)
DD (1) DD133151A5 (hu)
DE (1) DE2755122C2 (hu)
ES (2) ES465136A1 (hu)
FI (1) FI58135C (hu)
FR (1) FR2374336A1 (hu)
GB (1) GB1577633A (hu)
HU (1) HU176767B (hu)
IT (1) IT1113251B (hu)
PL (1) PL110178B1 (hu)
SU (2) SU751328A3 (hu)
ZA (1) ZA777494B (hu)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61158784U (hu) * 1985-03-25 1986-10-01
EP1108702A1 (en) * 1999-12-13 2001-06-20 Kvaerner Process Technology Limited Process for the co-production of aliphatic diols and cyclic ethers
WO2010102673A1 (en) * 2009-03-13 2010-09-16 Unibioscreen S.A. Hellebrin and hellebrigenin derivatives
PL2563803T3 (pl) * 2010-04-27 2016-08-31 Pharma Mar Sa Przeciwnowotworowe laktony steroidowe nienasycone w pozycji 7(8)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1901484A1 (de) * 1969-01-14 1970-10-29 Hoechst Ag Herzwirksame Oxyester von Steroid-Cardenoliden und -Bufandienoliden und Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
PL110178B1 (en) 1980-07-31
FI58135B (fi) 1980-08-29
SU751328A3 (ru) 1980-07-23
BE861968A (fr) 1978-06-16
PL203030A1 (pl) 1979-03-26
DD133151A5 (de) 1978-12-13
CH639107A5 (de) 1983-10-31
ES465135A1 (es) 1978-10-01
GB1577633A (en) 1980-10-29
AT372391B (de) 1983-09-26
JPS5395956A (en) 1978-08-22
DE2755122C2 (de) 1983-06-30
HU176767B (en) 1981-05-28
DE2755122A1 (de) 1978-06-22
FR2374336A1 (fr) 1978-07-13
JPS591279B2 (ja) 1984-01-11
FR2374336B1 (hu) 1980-11-07
FI773814A (fi) 1978-06-18
SU795487A3 (ru) 1981-01-07
ES465136A1 (es) 1979-01-01
IT1113251B (it) 1986-01-20
ZA777494B (en) 1979-02-28
ATA903877A (de) 1983-02-15

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MM Patent lapsed

Owner name: DEGUSSA AG