FI20011804A - Menetelmä ihmisen kantasolutekijän valmistamiseksi ja siihen soveltuva solu - Google Patents

Menetelmä ihmisen kantasolutekijän valmistamiseksi ja siihen soveltuva solu Download PDF

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Publication number
FI20011804A
FI20011804A FI20011804A FI20011804A FI20011804A FI 20011804 A FI20011804 A FI 20011804A FI 20011804 A FI20011804 A FI 20011804A FI 20011804 A FI20011804 A FI 20011804A FI 20011804 A FI20011804 A FI 20011804A
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FI
Finland
Prior art keywords
producing
human stem
stem cell
cell
factor
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FI20011804A
Other languages
English (en)
Swedish (sv)
Other versions
FI120312B (fi
Inventor
Krisztina M Zsebo
Robert A Bosselman
Sidney Vaughn Suggs
Francis Hall Martin
Original Assignee
Amgen Inc
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Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of FI20011804A publication Critical patent/FI20011804A/fi
Application granted granted Critical
Publication of FI120312B publication Critical patent/FI120312B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
FI20011804A 1989-10-16 2001-09-13 Ihmisen kantasolutekijän valmistamiseksi soveltuva solu FI120312B (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US42238389A 1989-10-16 1989-10-16
US42238389 1989-10-16
US53719890A 1990-06-11 1990-06-11
US53719890 1990-06-11
US57361690A 1990-08-24 1990-08-24
US57361690 1990-08-24
US9005548 1990-09-28
PCT/US1990/005548 WO1991005795A1 (en) 1989-10-16 1990-09-28 Stem cell factor

Publications (2)

Publication Number Publication Date
FI20011804A true FI20011804A (fi) 2001-09-13
FI120312B FI120312B (fi) 2009-09-15

Family

ID=27411345

Family Applications (2)

Application Number Title Priority Date Filing Date
FI912857A FI108140B (fi) 1989-10-16 1991-06-13 Menetelmä ja välineitä kantasolutekijän valmistamiseksi, valmistetun tuotteen käyttö, sitä sisältävä tarvikepakkaus sekä menetelmä kantasolutekijän vasta-aineen valmistamiseksi
FI20011804A FI120312B (fi) 1989-10-16 2001-09-13 Ihmisen kantasolutekijän valmistamiseksi soveltuva solu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI912857A FI108140B (fi) 1989-10-16 1991-06-13 Menetelmä ja välineitä kantasolutekijän valmistamiseksi, valmistetun tuotteen käyttö, sitä sisältävä tarvikepakkaus sekä menetelmä kantasolutekijän vasta-aineen valmistamiseksi

Country Status (17)

Country Link
US (1) US20080305074A1 (fi)
JP (1) JP2657113B2 (fi)
KR (2) KR100193050B1 (fi)
AU (3) AU6541090A (fi)
CA (8) CA2267668C (fi)
ES (2) ES2147720T3 (fi)
FI (2) FI108140B (fi)
GE (2) GEP20002145B (fi)
HU (2) HU220234B (fi)
IE (2) IE903562A1 (fi)
IL (4) IL127924A (fi)
LV (1) LV10462B (fi)
NO (3) NO303830B1 (fi)
NZ (1) NZ235571A (fi)
PT (1) PT95524B (fi)
RU (1) RU2212411C2 (fi)
WO (1) WO1991005795A1 (fi)

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US6562596B1 (en) 1993-10-06 2003-05-13 Amgen Inc. Tissue inhibitor of metalloproteinase type three (TIMP-3) composition and methods
US5459031A (en) * 1993-11-05 1995-10-17 Amgen Inc. Methods for controlling sialic acid derivatives in recombinant glycoproteins
JPH07165602A (ja) * 1993-12-16 1995-06-27 Kirin Brewery Co Ltd 放射線障害防護剤
US6288030B1 (en) 1993-12-22 2001-09-11 Amgen Inc. Stem cell factor formulations and methods
US6242417B1 (en) 1994-03-08 2001-06-05 Somatogen, Inc. Stabilized compositions containing hemoglobin
US5631219A (en) * 1994-03-08 1997-05-20 Somatogen, Inc. Method of stimulating hematopoiesis with hemoglobin
US5525708A (en) * 1994-03-28 1996-06-11 Cytomed, Inc. Covalent dimer of kit ligand
JPH11502845A (ja) 1995-03-31 1999-03-09 アラディグム コーポレーション 造血剤の肺内輸送
US5824789A (en) * 1995-06-07 1998-10-20 Systemix, Inc. Human growth factors, nucleotide sequence encoding growth factors, and method of use thereof
GB9515839D0 (en) * 1995-08-02 1995-10-04 Q One Biotech Ltd Feline stem cell factor
US5783186A (en) 1995-12-05 1998-07-21 Amgen Inc. Antibody-induced apoptosis
US5885962A (en) * 1996-04-05 1999-03-23 Amgen Inc. Stem cell factor analog compositions and method
US5969105A (en) * 1996-10-25 1999-10-19 Feng; Yiqing Stem cell factor receptor agonists
US6967092B1 (en) 1996-10-25 2005-11-22 Mc Kearn John P Multi-functional chimeric hematopoietic receptor agonists
JPH10158188A (ja) * 1996-11-29 1998-06-16 Senju Pharmaceut Co Ltd 角膜治療用組成物
US6017876A (en) 1997-08-15 2000-01-25 Amgen Inc. Chemical modification of granulocyte-colony stimulating factor (G-CSF) bioactivity
CA2301979A1 (en) * 1997-09-10 1999-03-18 Uab Research Foundation Regulation of osteoclast formation by inhibition of osteoblastic stem cell factor
US6541033B1 (en) 1998-06-30 2003-04-01 Amgen Inc. Thermosensitive biodegradable hydrogels for sustained delivery of leptin
US6420339B1 (en) 1998-10-14 2002-07-16 Amgen Inc. Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility
US6245740B1 (en) 1998-12-23 2001-06-12 Amgen Inc. Polyol:oil suspensions for the sustained release of proteins
US8106098B2 (en) 1999-08-09 2012-01-31 The General Hospital Corporation Protein conjugates with a water-soluble biocompatible, biodegradable polymer
AU784195B2 (en) 1999-11-12 2006-02-16 Baxter Biotech Technology S.A.R.L. Reduced side-effect hemoglobin compositions
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US20030191056A1 (en) 2002-04-04 2003-10-09 Kenneth Walker Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
US7081443B2 (en) 2002-05-21 2006-07-25 Korea Advanced Institutes Of Science And Technology (Kaist) Chimeric comp-ang1 molecule
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US7691365B2 (en) 2004-09-28 2010-04-06 Aprogen, Inc. Methods of using chimeric coiled coil molecule to treat ischemic disease
EP1817047B1 (en) 2004-11-05 2012-02-08 Northwestern University Use of scf and g-csf in the treatment of cerebral ischemia and neurological disorders
WO2007098548A1 (en) * 2006-03-01 2007-09-07 Apollo Life Sciences Limited A molecule and chimeric molecules thereof
PT2621519T (pt) 2010-09-28 2017-10-04 Aegerion Pharmaceuticals Inc Polipéptido de fusão de leptina-abd com duração de ação melhorada
US20150018408A1 (en) 2013-07-10 2015-01-15 The Regents Of The University Of Michigan Therapeutic antibodies and uses thereof
CN103547288B (zh) * 2011-01-10 2016-03-16 密执安大学评议会 干细胞因子抑制剂
US20150361150A1 (en) * 2013-02-04 2015-12-17 Roger Williams Medical Center Methods and compositions for treating gastrointestinal stromal tumor (gist)
CN109661462A (zh) * 2016-07-19 2019-04-19 阿塞尔塔有限公司 用于在悬浮下培养多能性干细胞的培养基
US11939373B2 (en) * 2019-09-16 2024-03-26 Opsidio, LLC Anti-stem cell factor antibodies and methods of blocking the interaction between SCF and c-Kit

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Also Published As

Publication number Publication date
IL170681A (en) 2010-04-15
PT95524A (pt) 1991-09-13
JP2657113B2 (ja) 1997-09-24
ES2147720T3 (es) 2000-10-01
NO316022B1 (no) 2003-12-01
IL127924A0 (en) 2000-02-17
RU2212411C2 (ru) 2003-09-20
HU220234B (hu) 2001-11-28
CA2026915C (en) 2006-11-28
AU6541090A (en) 1991-05-16
CA2026915A1 (en) 1991-04-17
KR100193050B1 (ko) 1999-06-15
CA2267658A1 (en) 1991-04-17
GEP20033145B (en) 2003-12-25
NO912321D0 (no) 1991-06-14
CA2267651A1 (en) 1991-04-17
CA2267651C (en) 2008-01-29
CA2267670A1 (en) 1991-04-17
NO982350L (no) 1998-05-22
NO982350D0 (no) 1998-05-22
FI108140B (fi) 2001-11-30
CA2267643A1 (en) 1991-04-17
NO912321L (no) 1991-08-16
AU712721B2 (en) 1999-11-11
AU1771297A (en) 1997-06-19
NO303830B1 (no) 1998-09-07
WO1991005795A1 (en) 1991-05-02
IE903562A1 (en) 1991-04-24
CA2267668C (en) 2008-02-19
GEP20002145B (en) 2000-06-25
NO964445L (no) 1996-10-18
KR920701238A (ko) 1992-08-11
NO964445D0 (no) 1996-10-18
CA2267668A1 (en) 1991-04-17
NZ235571A (en) 1997-06-24
IE20010893A1 (en) 2003-03-05
HU912386D0 (en) 1991-12-30
IL127924A (en) 2006-12-31
PT95524B (pt) 1997-08-29
CA2267671C (en) 2008-12-02
LV10462A (lv) 1995-02-20
HUT62011A (en) 1993-03-29
AU674570B2 (en) 1997-01-02
AU6060394A (en) 1994-07-07
ES2314999T3 (es) 2009-03-16
FI120312B (fi) 2009-09-15
US20080305074A1 (en) 2008-12-11
CA2267671A1 (en) 1991-04-17
JPH04502628A (ja) 1992-05-14
NO303831B1 (no) 1998-09-07
FI912857A0 (fi) 1991-06-13
KR100210241B1 (en) 1999-07-15
IL95905A0 (fi) 1991-07-18
CA2267626A1 (en) 1991-04-17
CA2267670C (en) 2005-01-11
IL95905A (en) 2002-02-10
LV10462B (en) 1996-04-20

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