FI120100B - Yhdistelmä-mersasidiini ja sen valmistusmenetelmä - Google Patents

Yhdistelmä-mersasidiini ja sen valmistusmenetelmä Download PDF

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Publication number
FI120100B
FI120100B FI954220A FI954220A FI120100B FI 120100 B FI120100 B FI 120100B FI 954220 A FI954220 A FI 954220A FI 954220 A FI954220 A FI 954220A FI 120100 B FI120100 B FI 120100B
Authority
FI
Finland
Prior art keywords
sequence
dna
amino acid
lantibiotics
mersacidin
Prior art date
Application number
FI954220A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI954220A (fi
FI954220A0 (fi
Inventor
Klaus-Peter Koller
Hans Georg Sahl
Gabriele Bierbaum
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI954220A0 publication Critical patent/FI954220A0/fi
Publication of FI954220A publication Critical patent/FI954220A/fi
Application granted granted Critical
Publication of FI120100B publication Critical patent/FI120100B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI954220A 1994-09-12 1995-09-08 Yhdistelmä-mersasidiini ja sen valmistusmenetelmä FI120100B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94114298 1994-09-12
EP94114298A EP0700998B1 (en) 1994-09-12 1994-09-12 Recombinant mersacidin and a method for production

Publications (3)

Publication Number Publication Date
FI954220A0 FI954220A0 (fi) 1995-09-08
FI954220A FI954220A (fi) 1996-03-13
FI120100B true FI120100B (fi) 2009-06-30

Family

ID=8216276

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954220A FI120100B (fi) 1994-09-12 1995-09-08 Yhdistelmä-mersasidiini ja sen valmistusmenetelmä

Country Status (19)

Country Link
US (1) US5667991A (cs)
EP (1) EP0700998B1 (cs)
JP (1) JPH0898695A (cs)
KR (1) KR100394289B1 (cs)
CN (1) CN1149287C (cs)
AT (1) ATE255165T1 (cs)
AU (1) AU696450B2 (cs)
CA (1) CA2157975C (cs)
CZ (1) CZ285741B6 (cs)
DE (1) DE69433357T2 (cs)
DK (1) DK0700998T3 (cs)
ES (1) ES2207636T3 (cs)
FI (1) FI120100B (cs)
HU (1) HU216619B (cs)
IL (1) IL115242A0 (cs)
NZ (1) NZ272960A (cs)
PT (1) PT700998E (cs)
RU (1) RU2198924C2 (cs)
SI (1) SI9500270B (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6775320B1 (en) * 1999-03-12 2004-08-10 Aware, Inc. Method and a multi-carrier transceiver supporting dynamic switching between active application sets
US6498808B1 (en) * 1999-03-12 2002-12-24 Aware, Inc. Seamless rate adaptive multicarrier modulation system and protocols
US6861236B2 (en) 2002-05-24 2005-03-01 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way
US7592308B2 (en) 2004-03-26 2009-09-22 Novacta Biosystems Limited F3W variants of the lantibiotic mersacidin and its use
GB0406870D0 (en) * 2004-03-26 2004-04-28 Novacta Biosystems Ltd Improvements relating to the production of lantibiotics
CA2623624A1 (en) * 2005-09-27 2007-04-05 Novacta Biosystems Limited Variants of the lantibiotic mersacidin and their use
GB0600928D0 (en) 2006-01-17 2006-02-22 Novacta Biosystems Ltd Improvements relating to lantibiotics
GB0714030D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd The use of type-B lantibiotic-based compounds having antimicrobial activity
GB0714029D0 (en) 2007-07-18 2007-08-29 Novacta Biosystems Ltd Lantibiotic-based compounds having antimicrobial activity
WO2009121483A1 (en) * 2008-04-02 2009-10-08 Sanofi-Aventis Highly bridged peptides from actinomadura namibiensis
CA2742753A1 (en) * 2008-11-24 2010-05-27 Sentinella Pharmaceuticals, Inc. ("Sentinella") Lantibiotic carboxyamide derivatives with enhanced antibacterial activity
RS53586B1 (en) 2009-01-14 2015-02-27 Novacta Biosystems Limited DERIVATION OF DECISION
SG173504A1 (en) 2009-02-04 2011-09-29 Novacta Biosystems Ltd Actagardine derivatives
GB201001688D0 (en) 2010-02-02 2010-03-17 Novacta Biosystems Ltd Compounds
GB201013513D0 (en) 2010-08-11 2010-09-22 Novacta Biosystems Ltd Formulations
CN106188253B (zh) * 2016-08-26 2020-08-18 上海交通大学 抗菌肽Lexapeptide及其制备方法和用途
JP2022519699A (ja) 2019-02-05 2022-03-24 エランコ・ユーエス・インコーポレイテッド 遺伝子改変ラクトバチルス（Ｌａｃｔｏｂａｃｉｌｌｕｓ）及びその使用
CN111235119B (zh) * 2020-03-05 2021-11-23 苏州十一方生物科技有限公司 一种融合抗菌蛋白的制备及应用
CN114457102B (zh) * 2022-02-24 2023-12-26 重庆市畜牧科学院 用于编码分泌型Mersacidin的基因表达盒及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5218101A (en) * 1988-07-05 1993-06-08 The University Of Maryland Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor
IN167138B (cs) * 1988-08-17 1990-09-01 Hoechst India

Also Published As

Publication number Publication date
HU216619B (hu) 1999-07-28
SI9500270B (sl) 2002-02-28
PT700998E (pt) 2004-03-31
DE69433357T2 (de) 2004-09-09
KR100394289B1 (ko) 2003-10-22
ATE255165T1 (de) 2003-12-15
CZ285741B6 (cs) 1999-10-13
SI9500270A (en) 1996-04-30
CA2157975C (en) 2008-11-18
CN1131192A (zh) 1996-09-18
KR960010863A (ko) 1996-04-20
JPH0898695A (ja) 1996-04-16
HUT73800A (en) 1996-09-30
EP0700998A1 (en) 1996-03-13
DE69433357D1 (de) 2004-01-08
RU2198924C2 (ru) 2003-02-20
AU3055495A (en) 1996-03-28
FI954220A (fi) 1996-03-13
EP0700998B1 (en) 2003-11-26
ES2207636T3 (es) 2004-06-01
US5667991A (en) 1997-09-16
CA2157975A1 (en) 1996-03-13
FI954220A0 (fi) 1995-09-08
CZ231895A3 (en) 1996-03-13
AU696450B2 (en) 1998-09-10
HU9502643D0 (en) 1995-11-28
CN1149287C (zh) 2004-05-12
NZ272960A (en) 1996-05-28
IL115242A0 (en) 1995-12-31
DK0700998T3 (da) 2004-03-29

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