FI116221B - Menetelmä (-)-N-metyyli-N-[4-(4-fenyyli-4-asetyyliaminopiperidin-1-yyli)-2-(3,4-dikloorifenyyli)butyyli]bentsamidin ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi - Google Patents
Menetelmä (-)-N-metyyli-N-[4-(4-fenyyli-4-asetyyliaminopiperidin-1-yyli)-2-(3,4-dikloorifenyyli)butyyli]bentsamidin ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi Download PDFInfo
- Publication number
- FI116221B FI116221B FI953994A FI953994A FI116221B FI 116221 B FI116221 B FI 116221B FI 953994 A FI953994 A FI 953994A FI 953994 A FI953994 A FI 953994A FI 116221 B FI116221 B FI 116221B
- Authority
- FI
- Finland
- Prior art keywords
- dichlorophenyl
- benzamide
- compound
- phenyl
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
- C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29403594 | 1994-08-24 | ||
US08/294,035 US5512680A (en) | 1993-02-26 | 1994-08-24 | Process for the preparation of an optically pure aminoalcohol |
Publications (3)
Publication Number | Publication Date |
---|---|
FI953994A0 FI953994A0 (fi) | 1995-08-24 |
FI953994A FI953994A (fi) | 1996-02-25 |
FI116221B true FI116221B (fi) | 2005-10-14 |
Family
ID=23131621
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI953994A FI116221B (fi) | 1994-08-24 | 1995-08-24 | Menetelmä (-)-N-metyyli-N-[4-(4-fenyyli-4-asetyyliaminopiperidin-1-yyli)-2-(3,4-dikloorifenyyli)butyyli]bentsamidin ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
Country Status (24)
Country | Link |
---|---|
US (2) | US5512680A (no) |
EP (1) | EP0698601B1 (no) |
JP (1) | JP3037592B2 (no) |
KR (1) | KR100275978B1 (no) |
AT (1) | ATE172964T1 (no) |
AU (1) | AU685971B2 (no) |
BR (1) | BR9503776A (no) |
CA (1) | CA2156764C (no) |
CZ (1) | CZ289654B6 (no) |
DE (1) | DE69505756T2 (no) |
DK (1) | DK0698601T3 (no) |
ES (1) | ES2125574T3 (no) |
FI (1) | FI116221B (no) |
HU (1) | HU218485B (no) |
IL (1) | IL114866A (no) |
MY (1) | MY116365A (no) |
NO (1) | NO305167B1 (no) |
NZ (1) | NZ272827A (no) |
PL (1) | PL182914B1 (no) |
RU (1) | RU2097376C1 (no) |
SI (1) | SI0698601T1 (no) |
SK (1) | SK281454B6 (no) |
TW (1) | TW410223B (no) |
ZA (1) | ZA957025B (no) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2792835B3 (fr) * | 1999-04-27 | 2001-05-25 | Sanofi Sa | Utilisation du saredutant pour la preparation de medicaments utiles dans le traitement ou la prevention de l'ensemble des troubles de l'humeur, des troubles de l'adaptation ou des troubles mixtes anxiete-depression |
WO2007020079A2 (en) * | 2005-08-17 | 2007-02-22 | Synthon B.V. | Orally disintegratable simvastatin tablets |
JP2009191006A (ja) * | 2008-02-14 | 2009-08-27 | Sumitomo Chemical Co Ltd | 光学活性な4−アミノ−3−(3,4−ジクロロフェニル)ブタン−1−オールの製造方法およびその中間体 |
EP3322691A4 (en) | 2015-07-13 | 2019-03-27 | Piramal Enterprises Limited | IMPROVED PROCESS FOR THE PREPARATION OF BACLOFEN AND ITS INTERMEDIATE |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI97540C (fi) | 1989-11-06 | 1997-01-10 | Sanofi Sa | Menetelmä terapeuttisesti käyttökelpoisten, aromaattisesti substituoitujen piperidiini- ja piperatsiinijohdannaisten valmistamiseksi |
IL99320A (en) | 1990-09-05 | 1995-07-31 | Sanofi Sa | Arylalkylamines, their preparation and pharmaceutical preparations containing them |
FR2676054B1 (fr) | 1991-05-03 | 1993-09-03 | Sanofi Elf | Nouveaux composes n-alkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
FR2688219B1 (fr) | 1992-03-03 | 1994-07-08 | Sanofi Elf | Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant. |
US5391819A (en) * | 1992-09-30 | 1995-02-21 | Merck & Co., Inc. | Process of making chiral 2-aryl-1,4-butanediamine derivatives as useful neurokinin-A antagonists |
FR2701946B1 (fr) * | 1993-02-26 | 1995-05-24 | Sanofi Elf | Procédé pour la préparation d'un aminoalcool optiquement pur. |
-
1994
- 1994-08-24 US US08/294,035 patent/US5512680A/en not_active Expired - Lifetime
-
1995
- 1995-08-08 IL IL11486695A patent/IL114866A/xx not_active IP Right Cessation
- 1995-08-16 MY MYPI95002400A patent/MY116365A/en unknown
- 1995-08-22 ZA ZA957025A patent/ZA957025B/xx unknown
- 1995-08-22 NZ NZ272827A patent/NZ272827A/en not_active IP Right Cessation
- 1995-08-22 SK SK1030-95A patent/SK281454B6/sk not_active IP Right Cessation
- 1995-08-23 AU AU30216/95A patent/AU685971B2/en not_active Ceased
- 1995-08-23 EP EP95401935A patent/EP0698601B1/en not_active Expired - Lifetime
- 1995-08-23 BR BR9503776A patent/BR9503776A/pt not_active Application Discontinuation
- 1995-08-23 DK DK95401935T patent/DK0698601T3/da active
- 1995-08-23 NO NO953313A patent/NO305167B1/no not_active IP Right Cessation
- 1995-08-23 ES ES95401935T patent/ES2125574T3/es not_active Expired - Lifetime
- 1995-08-23 SI SI9530196T patent/SI0698601T1/xx not_active IP Right Cessation
- 1995-08-23 CZ CZ19952164A patent/CZ289654B6/cs not_active IP Right Cessation
- 1995-08-23 CA CA002156764A patent/CA2156764C/en not_active Expired - Lifetime
- 1995-08-23 DE DE69505756T patent/DE69505756T2/de not_active Expired - Lifetime
- 1995-08-23 KR KR1019950026201A patent/KR100275978B1/ko not_active IP Right Cessation
- 1995-08-23 AT AT95401935T patent/ATE172964T1/de active
- 1995-08-23 RU RU95114391/04A patent/RU2097376C1/ru not_active IP Right Cessation
- 1995-08-24 FI FI953994A patent/FI116221B/fi not_active IP Right Cessation
- 1995-08-24 PL PL95310155A patent/PL182914B1/pl not_active IP Right Cessation
- 1995-08-24 HU HU9502481A patent/HU218485B/hu not_active IP Right Cessation
- 1995-08-24 JP JP7216328A patent/JP3037592B2/ja not_active Expired - Fee Related
- 1995-08-31 TW TW084109104A patent/TW410223B/zh not_active IP Right Cessation
-
1996
- 1996-02-07 US US08/598,001 patent/US5780666A/en not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2070196C1 (ru) | Арилалкиламины и фармацевтическая композиция на их основе | |
US5387603A (en) | 1,5,7-trisubstituted indoline compounds and salts thereof | |
FI103041B (fi) | Menetelmä lääkeaineina käyttökelpoisten N-alkyleenipiperidinoyhdisteid en ja niiden enantiomeerien valmistamiseksi | |
EP0559538B1 (fr) | Sels quaternaires de pipéridines 4-substitués, leur préparation et compositions pharmaceutiques les contenant | |
EP0434561B1 (fr) | Dérivés de la napht-1-yl pipérazine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent | |
FI95027C (fi) | Menetelmä terapeuttisesti käyttökelpoisten 3-substituoitujen pyrrolidiinijohdannaisten valmistamiseksi | |
EP0373998A1 (fr) | Ethers d'oxime de propénone, procédé pour leur préparation et compositions pharmaceutiques les contenant | |
WO1997014689A1 (fr) | Derives d'amines cycliques d'aryl-piperazines, leur preparation et les compositions pharmaceutiques les contenant | |
AU609359B2 (en) | New indolylpropanols, processes for their preparation and their use, and preparations containing the compounds | |
CS205087B2 (en) | Method of producing hydroxy-and oxoderivatives of aryloxy-and arylthio-perhydro-aza heterocycles | |
FI116221B (fi) | Menetelmä (-)-N-metyyli-N-[4-(4-fenyyli-4-asetyyliaminopiperidin-1-yyli)-2-(3,4-dikloorifenyyli)butyyli]bentsamidin ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi | |
HU186776B (en) | Process for preparing new, optically active imidazolidin-2-one derivatives | |
EP0364123B1 (en) | Muscarinic receptor antagonists | |
EP0429370B1 (fr) | Nouveaux dérivés du thiophène, leur procédé de préparation et les compositions pharmaceutiques les renfermant | |
WO1993012069A1 (en) | Novel amino alcohol derivative or salt thereof | |
EP0612716B1 (fr) | Procédé pour la préparation d'un aminoalcool optiquement pur | |
EP0649419A1 (fr) | Derives de la n-cycloalkylpiperazine, procedes d'obtention et compositions pharmaceutiques les contenant | |
EP1511728B1 (fr) | Derives d oxophenyl-cyclohexyl-propanolamine, leur preparati on et leur application en therapeutique | |
IE61393B1 (en) | Cyclobutenediones useful as intermediates | |
US4822792A (en) | Substituted 3-piperidinamines or 3-azepinamines, the preparation thereof and their applications in therapy | |
US5998666A (en) | Phenoxyethylamine derivatives, method of preparation, application as medicine and pharmaceutical compositions containing same | |
FR2633622A1 (fr) | Derives de sulfonyl indolizine, leur procede de preparation et leur utilisation comme intermediaires de synthese | |
SK3795A3 (en) | Derivatives of branched aminooxyaminoalkane inhibiting the orniting decarboxylasts, pharmaceutical agent containing them and method of their production | |
MXPA99002916A (en) | Novel phenoxyethylamine derivatives, method of preparation, application as medicine and pharmaceutical compositions containing same | |
CS205086B2 (cs) | Způsob výroby hydroxyderivátů aryloxy- a arylthioperhydroazaheterocyklů |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: SANOFI-AVENTIS |
|
FG | Patent granted |
Ref document number: 116221 Country of ref document: FI |
|
MM | Patent lapsed |