FI114549B - Menetelmä terapeuttisesti aktiivisten hydroksaamihappojohdannaisten valmistamiseksi - Google Patents
Menetelmä terapeuttisesti aktiivisten hydroksaamihappojohdannaisten valmistamiseksi Download PDFInfo
- Publication number
- FI114549B FI114549B FI950262A FI950262A FI114549B FI 114549 B FI114549 B FI 114549B FI 950262 A FI950262 A FI 950262A FI 950262 A FI950262 A FI 950262A FI 114549 B FI114549 B FI 114549B
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- FI
- Finland
- Prior art keywords
- eller
- hydroxy
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- atom
- methyl
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- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
- C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
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- C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
- C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
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- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
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- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
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- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| GB9215665 | 1992-07-23 | ||
| GB929215665A GB9215665D0 (en) | 1992-07-23 | 1992-07-23 | Compounds |
| GB9301557 | 1993-07-23 | ||
| PCT/GB1993/001557 WO1994002447A1 (en) | 1992-07-23 | 1993-07-23 | Hydroxamic acid derivatives as metalloproteinase inhibitors |
Publications (3)
| Publication Number | Publication Date |
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| FI950262A0 FI950262A0 (fi) | 1995-01-20 |
| FI950262A7 FI950262A7 (fi) | 1995-01-20 |
| FI114549B true FI114549B (fi) | 2004-11-15 |
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| FI950262A FI114549B (fi) | 1992-07-23 | 1995-01-20 | Menetelmä terapeuttisesti aktiivisten hydroksaamihappojohdannaisten valmistamiseksi |
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| NL122359C (cs) * | 1964-03-06 | |||
| IT1201443B (it) * | 1985-07-31 | 1989-02-02 | Zambon Spa | Intermedi per la sintesi di acidi carbossilici |
| US4599361A (en) * | 1985-09-10 | 1986-07-08 | G. D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
| DK77487A (da) * | 1986-03-11 | 1987-09-12 | Hoffmann La Roche | Hydroxylaminderivater |
| IT1198237B (it) * | 1986-12-23 | 1988-12-21 | Zambon Spa | Intermedi per la sintesi di composti organici |
| FR2609289B1 (fr) * | 1987-01-06 | 1991-03-29 | Bellon Labor Sa Roger | Nouveaux composes a activite d'inhibiteurs de collagenase, procede pour les preparer et compositions pharmaceutiques contenant ces composes |
| GB8827308D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
| GB8827305D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
| GB8919251D0 (en) * | 1989-08-24 | 1989-10-04 | British Bio Technology | Compounds |
| US5183900A (en) * | 1990-11-21 | 1993-02-02 | Galardy Richard E | Matrix metalloprotease inhibitors |
| EP0489579B1 (en) * | 1990-12-03 | 1995-03-29 | Celltech Therapeutics Limited | Peptidyl derivatives |
| CA2058797A1 (en) * | 1991-02-01 | 1992-08-02 | Michael John Broadhurst | Amino acid derivatives |
| GB9102635D0 (en) * | 1991-02-07 | 1991-03-27 | British Bio Technology | Compounds |
| JPH05125029A (ja) * | 1991-11-06 | 1993-05-21 | Yamanouchi Pharmaceut Co Ltd | 新規なアミド化合物又はその塩 |
| GB9307956D0 (en) * | 1993-04-17 | 1993-06-02 | Walls Alan J | Hydroxamic acid derivatives |
-
1992
- 1992-07-23 GB GB929215665A patent/GB9215665D0/en active Pending
-
1993
- 1993-07-22 GB GB9315206A patent/GB2268933B/en not_active Expired - Fee Related
- 1993-07-22 GB GB9500722A patent/GB2287023B/en not_active Expired - Fee Related
- 1993-07-22 GB GB9315222A patent/GB2268934B/en not_active Expired - Fee Related
- 1993-07-23 WO PCT/GB1993/001556 patent/WO1994002446A1/en active IP Right Grant
- 1993-07-23 RU RU95109920/04A patent/RU2126791C1/ru not_active IP Right Cessation
- 1993-07-23 EP EP96115235A patent/EP0754688B1/en not_active Expired - Lifetime
- 1993-07-23 UA UA95018066A patent/UA29450C2/uk unknown
- 1993-07-23 EP EP93917900A patent/EP0651738B1/en not_active Expired - Lifetime
- 1993-07-23 AU AU47153/93A patent/AU661410B2/en not_active Ceased
- 1993-07-23 DK DK93917901.6T patent/DK0651739T3/da active
- 1993-07-23 EP EP93917901A patent/EP0651739B1/en not_active Expired - Lifetime
- 1993-07-23 ES ES96115235T patent/ES2153927T3/es not_active Expired - Lifetime
- 1993-07-23 PL PL93307171A patent/PL174279B1/pl not_active IP Right Cessation
- 1993-07-23 CZ CZ95157A patent/CZ285896B6/cs not_active IP Right Cessation
- 1993-07-23 ZA ZA935352A patent/ZA935352B/xx unknown
- 1993-07-23 DE DE69316367T patent/DE69316367T2/de not_active Expired - Fee Related
- 1993-07-23 JP JP6504307A patent/JP2768554B2/ja not_active Expired - Fee Related
- 1993-07-23 KR KR1019950700232A patent/KR100205710B1/ko not_active Expired - Fee Related
- 1993-07-23 HU HU9500202A patent/HU220625B1/hu not_active IP Right Cessation
- 1993-07-23 AT AT93917901T patent/ATE151414T1/de not_active IP Right Cessation
- 1993-07-23 DE DE69329804T patent/DE69329804T2/de not_active Expired - Fee Related
- 1993-07-23 DK DK96115235T patent/DK0754688T3/da active
- 1993-07-23 SK SK78-95A patent/SK281240B6/sk unknown
- 1993-07-23 NZ NZ254862A patent/NZ254862A/en not_active IP Right Cessation
- 1993-07-23 AU AU47152/93A patent/AU4715293A/en not_active Abandoned
- 1993-07-23 CA CA002140626A patent/CA2140626C/en not_active Expired - Fee Related
- 1993-07-23 AT AT96115235T patent/ATE198331T1/de not_active IP Right Cessation
- 1993-07-23 WO PCT/GB1993/001557 patent/WO1994002447A1/en active IP Right Grant
- 1993-07-23 AT AT93917900T patent/ATE162183T1/de active
- 1993-07-23 ZA ZA935351A patent/ZA935351B/xx unknown
- 1993-07-23 DE DE4393452T patent/DE4393452T1/de not_active Ceased
- 1993-07-23 DE DE9321495U patent/DE9321495U1/de not_active Expired - Lifetime
- 1993-07-23 JP JP6504306A patent/JPH07509459A/ja active Pending
- 1993-07-23 PT PT96115235T patent/PT754688E/pt unknown
- 1993-07-23 DE DE69309686T patent/DE69309686T2/de not_active Expired - Fee Related
- 1993-07-23 US US08/374,601 patent/US5643964A/en not_active Expired - Fee Related
- 1993-07-23 US US08/374,602 patent/US5700838A/en not_active Expired - Fee Related
-
1995
- 1995-01-20 NO NO950226A patent/NO303221B1/no unknown
- 1995-01-20 FI FI950262A patent/FI114549B/fi not_active IP Right Cessation
- 1995-06-12 HU HU95P/P00187P patent/HU211287A9/hu unknown
-
1996
- 1996-08-08 HK HK149396A patent/HK149396A/xx not_active IP Right Cessation
-
1997
- 1997-05-16 CY CY194497A patent/CY1944A/en unknown
- 1997-05-23 GR GR970401170T patent/GR3023522T3/el unknown
- 1997-10-23 US US08/956,338 patent/US5912360A/en not_active Expired - Lifetime
- 1997-12-22 JP JP9353810A patent/JP2971053B2/ja not_active Expired - Fee Related
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2001
- 2001-03-05 GR GR20010400350T patent/GR3035510T3/el not_active IP Right Cessation
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