FI114470B - Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä - Google Patents
Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä Download PDFInfo
- Publication number
- FI114470B FI114470B FI970771A FI970771A FI114470B FI 114470 B FI114470 B FI 114470B FI 970771 A FI970771 A FI 970771A FI 970771 A FI970771 A FI 970771A FI 114470 B FI114470 B FI 114470B
- Authority
- FI
- Finland
- Prior art keywords
- ethyl
- carbonyl
- pyrrolidine
- benzoimidazole
- piperidin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29596094A | 1994-08-25 | 1994-08-25 | |
US29596094 | 1994-08-25 | ||
US50191495A | 1995-07-13 | 1995-07-13 | |
US50191495 | 1995-07-13 | ||
PCT/US1995/010640 WO1996006094A1 (en) | 1994-08-25 | 1995-08-17 | Novel substituted piperidines useful for the treatment of allergic diseases |
US9510640 | 1995-08-17 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI970771A FI970771A (fi) | 1997-02-24 |
FI970771A0 FI970771A0 (fi) | 1997-02-24 |
FI114470B true FI114470B (fi) | 2004-10-29 |
Family
ID=26969426
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI970771A FI114470B (fi) | 1994-08-25 | 1997-02-24 | Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä |
Country Status (20)
Country | Link |
---|---|
US (1) | US6329392B1 (hu) |
EP (1) | EP0777666B1 (hu) |
JP (1) | JPH10504580A (hu) |
KR (1) | KR100362620B1 (hu) |
CN (1) | CN1067385C (hu) |
AT (1) | ATE177095T1 (hu) |
AU (1) | AU693936B2 (hu) |
CA (1) | CA2198084C (hu) |
DE (1) | DE69508093T2 (hu) |
DK (1) | DK0777666T3 (hu) |
ES (1) | ES2132709T3 (hu) |
FI (1) | FI114470B (hu) |
GR (1) | GR3030253T3 (hu) |
HU (1) | HU221434B (hu) |
IL (1) | IL115040A (hu) |
MX (1) | MX9701305A (hu) |
NO (1) | NO313237B1 (hu) |
NZ (1) | NZ292683A (hu) |
TW (1) | TW430663B (hu) |
WO (1) | WO1996006094A1 (hu) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6211199B1 (en) | 1995-11-17 | 2001-04-03 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases |
PT920425E (pt) * | 1995-11-17 | 2003-07-31 | Aventis Pharma Inc | 4-(1h-benzimidazol-2-il-amino)piperidinas substituidas uteis para o tratamento de doencas alergicas |
US6194406B1 (en) | 1995-12-20 | 2001-02-27 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease |
ES2177827T3 (es) * | 1995-12-20 | 2002-12-16 | Aventis Pharma Inc | 4-(1h-bencimidazol-2-il)(1,4)diazepanes utiles para el tratamiento de enfermedades alergicas. |
US6423704B2 (en) | 1995-12-20 | 2002-07-23 | Aventis Pharmaceuticals Inc. | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases |
CN1115341C (zh) * | 1996-02-21 | 2003-07-23 | 阿温蒂斯药物公司 | 用于治疗过敏性疾病的新的取代的n-甲基-n-(4-(4-(1h-苯并咪唑-2-基氨基)哌啶-1-基)-2-(芳基)丁基)苯甲酰胺 |
KR19990087130A (ko) * | 1996-02-21 | 1999-12-15 | 게리 디. 스트리트, 스티븐 엘. 네스비트 | 알레르기성 질환의 치료에 유용한 신규한 치환된 n-메틸-n-(4-(4-(1h-벤즈이미다졸-2-일)[1,4]디아제판-1-일)-2-(아릴)부틸)벤즈아미드 |
US5932571A (en) * | 1996-02-21 | 1999-08-03 | Hoechst Marion Roussel, Inc. | Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases |
US5998439A (en) * | 1996-02-21 | 1999-12-07 | Hoescht Marion Roussel, Inc. | Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases |
FR2755133B1 (fr) * | 1996-10-31 | 1999-01-15 | Sanofi Sa | Nouveaux derives d'amides cycliques diversement substitues antagonistes selectifs du recepteur nk3 humain, procede pour leur obtention et compositions pharmaceutiques les contenant |
FR2759584B1 (fr) * | 1997-02-17 | 1999-06-11 | Sanofi Sa | Composition pharmaceutique pour l'administration orale de composes heterocycliques sous forme ammonium quaternaire |
FR2759585B1 (fr) * | 1997-02-17 | 1999-06-11 | Sanofi Sa | Formulations pharmaceutiques presentees sous forme seche pour l'administration orale d'un compose ammonium quaternaire cyclique |
GB9821898D0 (en) * | 1998-10-08 | 1998-12-02 | Pfizer Ltd | Heterocycles |
US6103735A (en) * | 1998-10-09 | 2000-08-15 | Schering Corporation | Composition and method for treating allergic diseases |
WO2000021512A2 (en) * | 1998-10-09 | 2000-04-20 | Schering Corporation | Composition and method for treating allergic diseases |
FR2789390B3 (fr) | 1999-02-10 | 2001-03-09 | Sanofi Sa | Nouveaux derives de piperidine, procede pour leur obtention et compositions pharmaceutiques les contenant |
BR0107624A (pt) | 2000-01-17 | 2002-11-12 | Bayer Ag | Arilcetonas substituìdas |
JP2005511475A (ja) * | 2001-03-02 | 2005-04-28 | ブリストル−マイヤーズ スクイブ カンパニー | メラノコルチン受容体のモジュレーターとして有用な化合物及びそれを含む製薬組成物 |
SE0302116D0 (sv) * | 2003-07-21 | 2003-07-21 | Astrazeneca Ab | Novel compounds |
GB0326407D0 (en) * | 2003-11-12 | 2003-12-17 | Glaxo Group Ltd | Chemical compounds |
KR101412339B1 (ko) | 2004-07-15 | 2014-06-25 | 알바니 몰레큘라 리써치, 인크. | 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를차단하기 위한 용도 |
US8362075B2 (en) | 2005-05-17 | 2013-01-29 | Merck Sharp & Dohme Corp. | Cyclohexyl sulphones for treatment of cancer |
NZ565111A (en) | 2005-07-15 | 2011-10-28 | Amr Technology Inc | Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
WO2007041052A2 (en) | 2005-09-29 | 2007-04-12 | Merck & Co., Inc. | Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators |
GB0603041D0 (en) | 2006-02-15 | 2006-03-29 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
WO2008039327A2 (en) | 2006-09-22 | 2008-04-03 | Merck & Co., Inc. | Method of treatment using fatty acid synthesis inhibitors |
US20110218176A1 (en) | 2006-11-01 | 2011-09-08 | Barbara Brooke Jennings-Spring | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
WO2008084261A1 (en) | 2007-01-10 | 2008-07-17 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa | Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors |
EP2117538A1 (en) | 2007-01-24 | 2009-11-18 | Glaxo Group Limited | Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-) |
US8106086B2 (en) | 2007-04-02 | 2012-01-31 | Msd K.K. | Indoledione derivative |
EP2170076B1 (en) | 2007-06-27 | 2016-05-18 | Merck Sharp & Dohme Corp. | 4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
CA2717509A1 (en) | 2008-03-03 | 2009-09-11 | Tiger Pharmatech | Tyrosine kinase inhibitors |
US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
WO2010114780A1 (en) | 2009-04-01 | 2010-10-07 | Merck Sharp & Dohme Corp. | Inhibitors of akt activity |
US7918821B2 (en) | 2009-05-05 | 2011-04-05 | Mahurkar Sakharam D | Universal safety syringe |
CN102595902B (zh) | 2009-05-12 | 2015-04-29 | 阿尔巴尼分子研究公司 | 7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途 |
WO2010132487A1 (en) | 2009-05-12 | 2010-11-18 | Bristol-Myers Squibb Company | CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF |
ES2446971T3 (es) | 2009-05-12 | 2014-03-11 | Albany Molecular Research, Inc. | Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso |
AU2010291834A1 (en) * | 2009-09-04 | 2012-03-15 | Zalicus Pharmaceuticals Ltd. | Substituted heterocyclic derivatives for the treatment of pain and epilepsy |
NZ599343A (en) | 2009-10-14 | 2014-05-30 | Merck Sharp & Dohme | Substituted piperidines that increase p53 activity and the uses thereof |
WO2011163330A1 (en) | 2010-06-24 | 2011-12-29 | Merck Sharp & Dohme Corp. | Novel heterocyclic compounds as erk inhibitors |
US8518907B2 (en) | 2010-08-02 | 2013-08-27 | Merck Sharp & Dohme Corp. | RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA) |
RU2624045C2 (ru) | 2010-08-17 | 2017-06-30 | Сирна Терапьютикс,Инк | ОПОСРЕДУЕМОЕ РНК-ИНТЕРФЕРЕНЦИЕЙ ИНГИБИРОВАНИЕ ЭКСПРЕССИИ ГЕНОВ ВИРУСА ГЕПАТИТА B (HBV) С ПРИМЕНЕНИЕМ МАЛОЙ ИНТЕРФЕРИРУЮЩЕЙ НУКЛЕИНОВОЙ КИСЛОТЫ (миНК) |
EP2608669B1 (en) | 2010-08-23 | 2016-06-22 | Merck Sharp & Dohme Corp. | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS |
WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
WO2012036997A1 (en) | 2010-09-16 | 2012-03-22 | Schering Corporation | Fused pyrazole derivatives as novel erk inhibitors |
WO2012058210A1 (en) | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA) |
EP2654748B1 (en) | 2010-12-21 | 2016-07-27 | Merck Sharp & Dohme Corp. | Indazole derivatives useful as erk inhibitors |
US20140045832A1 (en) | 2011-04-21 | 2014-02-13 | Piramal Enterprises Limited | Insulin-Like Growth Factor-1 Receptor Inhibitors |
WO2013063214A1 (en) | 2011-10-27 | 2013-05-02 | Merck Sharp & Dohme Corp. | Novel compounds that are erk inhibitors |
EP3358013B1 (en) | 2012-05-02 | 2020-06-24 | Sirna Therapeutics, Inc. | Short interfering nucleic acid (sina) compositions |
US9233979B2 (en) | 2012-09-28 | 2016-01-12 | Merck Sharp & Dohme Corp. | Compounds that are ERK inhibitors |
PT2925888T (pt) | 2012-11-28 | 2017-12-13 | Merck Sharp & Dohme | Composições e métodos para tratamento do cancro |
CA2895504A1 (en) | 2012-12-20 | 2014-06-26 | Merck Sharp & Dohme Corp. | Substituted imidazopyridines as hdm2 inhibitors |
WO2014120748A1 (en) | 2013-01-30 | 2014-08-07 | Merck Sharp & Dohme Corp. | 2,6,7,8 substituted purines as hdm2 inhibitors |
US10208023B2 (en) | 2013-03-01 | 2019-02-19 | Mark G. DeGiacomo | Heterocyclic inhibitors of the sodium channel |
US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
WO2018169818A1 (en) * | 2017-03-12 | 2018-09-20 | Xiaodong Wang | Polycyclic amines as opioid receptor modulators |
US10947234B2 (en) | 2017-11-08 | 2021-03-16 | Merck Sharp & Dohme Corp. | PRMT5 inhibitors |
WO2020033282A1 (en) | 2018-08-07 | 2020-02-13 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
EP3833667B1 (en) | 2018-08-07 | 2024-03-13 | Merck Sharp & Dohme LLC | Prmt5 inhibitors |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR517589A (fr) | 1920-06-22 | 1921-05-07 | Simon Et Muller | Soc de charrue |
US3282947A (en) | 1962-05-17 | 1966-11-01 | Geschickter Fund Med Res | Unsymmetrically substituted 3, 9-diazaspiro(5, 5)undecane compounds |
BE794598A (fr) | 1972-01-28 | 1973-05-16 | Richardson Merrell Inc | Nouveaux derives olefiniques de piperidines substituees en 4 et leur procede de preparation |
JPS6157311B2 (hu) | 1975-01-16 | 1986-12-06 | Robins Co Inc A H | |
US4254130A (en) | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
US4254129A (en) | 1979-04-10 | 1981-03-03 | Richardson-Merrell Inc. | Piperidine derivatives |
US4285958A (en) | 1979-04-10 | 1981-08-25 | Richardson-Merrell Inc. | 1-Piperidine-alkylene ketones, pharmaceutical compositions thereof and method of use thereof |
JPS5790018A (en) | 1980-11-27 | 1982-06-04 | Toray Ind Inc | Stabilized polyphenylene sulfide and its production |
DE3132882A1 (de) | 1981-08-20 | 1983-03-03 | Cassella Ag, 6000 Frankfurt | Neue piperazinone, ihre herstellung und verwendung |
US4666905A (en) | 1983-06-02 | 1987-05-19 | Warner-Lambert Company | Diphenylmethylene piperidines compositions and methods for their use |
GB8321157D0 (en) | 1983-08-05 | 1983-09-07 | Fordonal Sa | Piperidine derivatives |
EP0360390A1 (en) | 1988-07-25 | 1990-03-28 | Glaxo Group Limited | Spirolactam derivatives |
US4908372A (en) | 1988-10-13 | 1990-03-13 | Merrell Dow Pharmaceuticals Inc. | Antihistaminic piperidinyl benzimidazoles |
IE903957A1 (en) | 1989-11-06 | 1991-05-08 | Sanofi Sa | Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present |
IL99320A (en) | 1990-09-05 | 1995-07-31 | Sanofi Sa | Arylalkylamines, their preparation and pharmaceutical preparations containing them |
WO1992006086A1 (en) | 1990-10-01 | 1992-04-16 | Janssen Pharmaceutica N.V. | Novel 4-piperidinylcarbonyl derivatives |
GB9023116D0 (en) | 1990-10-24 | 1990-12-05 | Fujisawa Pharmaceutical Co | Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same |
FR2676053B1 (fr) | 1991-05-03 | 1993-08-27 | Sanofi Elf | Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
FR2676055B1 (fr) | 1991-05-03 | 1993-09-03 | Sanofi Elf | Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant. |
GB9113219D0 (en) | 1991-06-19 | 1991-08-07 | Fujisawa Pharmaceutical Co | Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same |
TW202432B (hu) | 1991-06-21 | 1993-03-21 | Pfizer | |
AU2031692A (en) | 1991-07-22 | 1993-01-28 | Zyma S.A. | Arylalkylamine derivatives |
GB9200535D0 (en) | 1992-01-10 | 1992-02-26 | Fujisawa Pharmaceutical Co | New compound |
FR2688219B1 (fr) | 1992-03-03 | 1994-07-08 | Sanofi Elf | Sels d'ammonium quaternaires de composes aromatiques amines, leur preparation et compositions pharmaceutiques les contenant. |
ES2048109B1 (es) | 1992-07-20 | 1994-12-16 | Espanola Prod Quimicos | Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol. |
ATE158580T1 (de) | 1993-05-06 | 1997-10-15 | Merrell Pharma Inc | Substituierte pyrrolidin-3-alkyl-piperidine verwendbar als tachykinin-antagonisten |
-
1995
- 1995-08-17 HU HU9701257A patent/HU221434B/hu not_active IP Right Cessation
- 1995-08-17 CA CA002198084A patent/CA2198084C/en not_active Expired - Fee Related
- 1995-08-17 NZ NZ292683A patent/NZ292683A/en unknown
- 1995-08-17 DK DK95931551T patent/DK0777666T3/da active
- 1995-08-17 AT AT95931551T patent/ATE177095T1/de not_active IP Right Cessation
- 1995-08-17 WO PCT/US1995/010640 patent/WO1996006094A1/en active IP Right Grant
- 1995-08-17 ES ES95931551T patent/ES2132709T3/es not_active Expired - Lifetime
- 1995-08-17 DE DE69508093T patent/DE69508093T2/de not_active Expired - Fee Related
- 1995-08-17 MX MX9701305A patent/MX9701305A/es unknown
- 1995-08-17 JP JP8508257A patent/JPH10504580A/ja not_active Ceased
- 1995-08-17 KR KR1019970701189A patent/KR100362620B1/ko not_active IP Right Cessation
- 1995-08-17 CN CN95195283A patent/CN1067385C/zh not_active Expired - Fee Related
- 1995-08-17 AU AU34928/95A patent/AU693936B2/en not_active Ceased
- 1995-08-17 EP EP95931551A patent/EP0777666B1/en not_active Expired - Lifetime
- 1995-08-23 TW TW084108797A patent/TW430663B/zh not_active IP Right Cessation
- 1995-08-23 IL IL11504095A patent/IL115040A/xx not_active IP Right Cessation
-
1997
- 1997-02-24 NO NO19970831A patent/NO313237B1/no unknown
- 1997-02-24 FI FI970771A patent/FI114470B/fi not_active IP Right Cessation
-
1998
- 1998-05-15 US US09/079,924 patent/US6329392B1/en not_active Expired - Fee Related
-
1999
- 1999-05-19 GR GR990401346T patent/GR3030253T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
TW430663B (en) | 2001-04-21 |
US6329392B1 (en) | 2001-12-11 |
CA2198084A1 (en) | 1996-02-29 |
IL115040A0 (en) | 1995-12-08 |
AU693936B2 (en) | 1998-07-09 |
EP0777666B1 (en) | 1999-03-03 |
WO1996006094A1 (en) | 1996-02-29 |
DE69508093D1 (de) | 1999-04-08 |
CN1067385C (zh) | 2001-06-20 |
JPH10504580A (ja) | 1998-05-06 |
KR100362620B1 (ko) | 2003-02-14 |
EP0777666A1 (en) | 1997-06-11 |
NZ292683A (en) | 1998-07-28 |
FI970771A (fi) | 1997-02-24 |
MX9701305A (es) | 1998-05-31 |
IL115040A (en) | 2000-02-29 |
NO970831D0 (no) | 1997-02-24 |
DK0777666T3 (da) | 1999-09-27 |
GR3030253T3 (en) | 1999-08-31 |
HUT76644A (en) | 1997-10-28 |
ES2132709T3 (es) | 1999-08-16 |
KR970705556A (ko) | 1997-10-09 |
ATE177095T1 (de) | 1999-03-15 |
AU3492895A (en) | 1996-03-14 |
FI970771A0 (fi) | 1997-02-24 |
DE69508093T2 (de) | 1999-07-15 |
HU221434B (en) | 2002-10-28 |
NO970831L (no) | 1997-04-18 |
NO313237B1 (no) | 2002-09-02 |
CA2198084C (en) | 2000-03-28 |
CN1158612A (zh) | 1997-09-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI114470B (fi) | Uusia allergisten sairauksien hoidossa käyttökelpoisia substituoituja piperidiinejä | |
AU679045B2 (en) | Benzimidazole derivatives | |
US7479559B2 (en) | Benzyl(idene)-lactam derivatives | |
NO310913B1 (no) | 1-(1,2-disubstituert piperidinyl)-4-substituert piperidinderivater som tachykinin reseptorantagonister | |
CZ293134B6 (cs) | Substituované heterocyklické sloučeniny, způsob jejich přípravy, meziprodukty tohoto způsobu a farmaceutický prostředek obsahující tyto sloučeniny | |
WO2007015162A1 (en) | Piperidinoyl-pyrrolidine and piperidinoyl-piperidine compounds | |
CA2155320A1 (en) | Substituted acetamide compound | |
WO2008020607A1 (fr) | Dérivé de phtalide et sel de celui-ci | |
US7060836B2 (en) | Lactams as tachykinin antagonists | |
US6716837B1 (en) | Heterocyclic compounds for the treatment of migraine | |
US5576336A (en) | Indole derivatives as dopamine D4 antagonists | |
AU703701B2 (en) | Substituted 4-(1H-benzimidazol-2-YL-amino)piperidines useful for the treatment of allergic diseases | |
US6423704B2 (en) | Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases | |
RU2158264C2 (ru) | 3-азетидинилалкилпиперидины или пирролидины в качестве антагонистов тахикинина, способы их получения, промежуточные соединения, фармацевтическая композиция на их основе и способ лечения | |
KR101304802B1 (ko) | 3-(벤질아미노)-피롤리딘 유도체 및 이의 nk-3 수용체 길항제로서의 용도 | |
EP0635014B1 (en) | Indole derivatives as 5-ht1-like agonists | |
AU707914B2 (en) | Novel substituted 4-(1H-benzimidazol-2-yl){1,4}diazepanes useful for the treatment of allergic diseases | |
AU2001232319B2 (en) | Phenoxyalkylamine derivates useful as opioid delta receptor ligands | |
AU709215B2 (en) | Novel substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases | |
JPH08301868A (ja) | 置換ヘテロ環 | |
US20150011526A1 (en) | 2-Oxo-Piperidinyl Derivatives | |
Krushinski Jr et al. | 5-HT 1F agonists |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Patent granted |
Ref document number: 114470 Country of ref document: FI |
|
MA | Patent expired |