FI113773B - Menetelmä verisuonia supistavien substituoitujen dihydropyranopyridiinien valmistamiseksi - Google Patents

Menetelmä verisuonia supistavien substituoitujen dihydropyranopyridiinien valmistamiseksi Download PDF

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Publication number
FI113773B
FI113773B FI960721A FI960721A FI113773B FI 113773 B FI113773 B FI 113773B FI 960721 A FI960721 A FI 960721A FI 960721 A FI960721 A FI 960721A FI 113773 B FI113773 B FI 113773B
Authority
FI
Finland
Prior art keywords
formula
group
hydrogen
pyrano
dihydro
Prior art date
Application number
FI960721A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI960721A0 (fi
FI960721A7 (fi
Inventor
Lommen Guy Rosalia Eugene Van
Francisco Javi Fernandez-Gadea
Jose Ignacio Andres-Gil
Maria Enc Matesanz-Ballesteros
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI960721A0 publication Critical patent/FI960721A0/fi
Publication of FI960721A7 publication Critical patent/FI960721A7/fi
Application granted granted Critical
Publication of FI113773B publication Critical patent/FI113773B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI960721A 1993-08-19 1996-02-16 Menetelmä verisuonia supistavien substituoitujen dihydropyranopyridiinien valmistamiseksi FI113773B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP93202440 1993-08-19
EP93202440 1993-08-19
PCT/EP1994/002700 WO1995005381A1 (en) 1993-08-19 1994-08-12 Vasoconstrictive substituted dihydropyranopyridines
EP9402700 1994-08-12

Publications (3)

Publication Number Publication Date
FI960721A0 FI960721A0 (fi) 1996-02-16
FI960721A7 FI960721A7 (fi) 1996-02-16
FI113773B true FI113773B (fi) 2004-06-15

Family

ID=8214053

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960721A FI113773B (fi) 1993-08-19 1996-02-16 Menetelmä verisuonia supistavien substituoitujen dihydropyranopyridiinien valmistamiseksi

Country Status (27)

Country Link
US (1) US5691344A (cs)
EP (1) EP0714395B1 (cs)
JP (1) JP3650398B2 (cs)
KR (1) KR100330697B1 (cs)
CN (1) CN1051085C (cs)
AT (1) ATE178330T1 (cs)
AU (1) AU684819B2 (cs)
BR (1) BR9407298A (cs)
CA (1) CA2168022C (cs)
CZ (1) CZ286645B6 (cs)
DE (1) DE69417560T2 (cs)
DK (1) DK0714395T3 (cs)
ES (1) ES2132424T3 (cs)
FI (1) FI113773B (cs)
GR (1) GR3029924T3 (cs)
HU (1) HU228673B1 (cs)
IL (1) IL110688A (cs)
MY (1) MY111419A (cs)
NO (1) NO315001B1 (cs)
NZ (1) NZ271383A (cs)
PL (1) PL177516B1 (cs)
RO (1) RO116729B1 (cs)
RU (1) RU2135501C1 (cs)
SI (1) SI0714395T1 (cs)
SK (1) SK282108B6 (cs)
WO (1) WO1995005381A1 (cs)
ZA (1) ZA946268B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
DE19950647A1 (de) * 1999-10-21 2001-04-26 Merck Patent Gmbh Imidazolderivate als Phosphodiesterase VII-Hemmer
US6818659B2 (en) 2001-11-06 2004-11-16 Bristol-Myers Squibb Pharma, Inc. (2S)-2-amino-4-(2-amino-(3,4,5,6-tetrahydropyrimidin-4-yl) butanoyl and its use in cyclic and acyclic peptides
CN109476675B (zh) * 2016-07-01 2022-12-09 爱尔兰詹森科学公司 用于治疗病毒性感染的二氢吡喃并嘧啶衍生物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU403673A1 (ru) * 1971-10-05 1973-10-26 Авторы изобретени витель Способ получения 2-амино-4н-пирано
SU466228A1 (ru) * 1973-02-28 1975-04-05 Дальневосточный государственный университет Способ получени 2,4-дифенил-7,7диметилтетрагидропирано(4,3-в)пиперидина
SU943240A1 (ru) * 1980-05-28 1982-07-15 Пермский государственный фармацевтический институт Способ получени производных 10-окси-10н-пиридо [2,3- @ ХРОМЕНОВ
US4405622A (en) * 1980-10-16 1983-09-20 Syntex (U.S.A.) Inc. [1-(1,4-Benzodioxan-2-yl)-4-(4-aminopyrimidin-2-yl]piperazines useful as anti-depressants
AU576868B2 (en) * 1984-06-11 1988-09-08 E.I. Du Pont De Nemours And Company Thiophene and pyridine sulfonamides
FR2615191B1 (fr) * 1987-05-16 1991-01-11 Sandoz Sa Nouveaux benzo(b)pyrannes et pyrannopyridines, leur preparation et leur utilisation comme medicaments
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
US5140031A (en) * 1989-05-31 1992-08-18 E. R. Squibb & Sons, Inc. Pyranyl cyanoguanidine derivatives
US5250450A (en) * 1991-04-08 1993-10-05 Micron Technology, Inc. Insulated-gate vertical field-effect transistor with high current drive and minimum overlap capacitance
DE4120322A1 (de) * 1991-06-20 1992-12-24 Bayer Ag Aminomethyl-substituierte 2,3-dihydropyrano(2,3-b)pyridine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines

Also Published As

Publication number Publication date
FI960721A0 (fi) 1996-02-16
CZ37396A3 (en) 1996-05-15
WO1995005381A1 (en) 1995-02-23
DE69417560T2 (de) 1999-11-11
CN1051085C (zh) 2000-04-05
NO315001B1 (no) 2003-06-23
SK282108B6 (sk) 2001-11-06
RU2135501C1 (ru) 1999-08-27
NO960647D0 (no) 1996-02-19
MY111419A (en) 2000-04-29
US5691344A (en) 1997-11-25
CZ286645B6 (cs) 2000-05-17
DE69417560D1 (de) 1999-05-06
KR100330697B1 (ko) 2002-10-04
DK0714395T3 (da) 1999-10-11
NO960647L (no) 1996-02-19
HU228673B1 (en) 2013-05-28
ATE178330T1 (de) 1999-04-15
HU9600374D0 (en) 1996-04-29
EP0714395B1 (en) 1999-03-31
FI960721A7 (fi) 1996-02-16
AU684819B2 (en) 1998-01-08
CA2168022A1 (en) 1995-02-23
AU7499594A (en) 1995-03-14
BR9407298A (pt) 1996-10-01
GR3029924T3 (en) 1999-07-30
NZ271383A (en) 1997-05-26
IL110688A0 (en) 1994-11-11
CA2168022C (en) 2006-11-21
JPH09501669A (ja) 1997-02-18
RO116729B1 (ro) 2001-05-30
SI0714395T1 (en) 1999-08-31
SK19496A3 (en) 1997-02-05
EP0714395A1 (en) 1996-06-05
CN1129943A (zh) 1996-08-28
PL177516B1 (pl) 1999-12-31
PL313080A1 (en) 1996-05-27
ES2132424T3 (es) 1999-08-16
IL110688A (en) 1998-10-30
ZA946268B (en) 1996-02-19
HUT74676A (en) 1997-01-28
JP3650398B2 (ja) 2005-05-18

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