DE69517768T2 - IMIDAZOLYLALKYLDERIVATE VON IMIDAZO [5,1-c][1,4]BENZOXAZIN-1-ON UND IHRE VERWENDUNG ALS ARZNEIMITTEL - Google Patents
IMIDAZOLYLALKYLDERIVATE VON IMIDAZO [5,1-c][1,4]BENZOXAZIN-1-ON UND IHRE VERWENDUNG ALS ARZNEIMITTELInfo
- Publication number
- DE69517768T2 DE69517768T2 DE69517768T DE69517768T DE69517768T2 DE 69517768 T2 DE69517768 T2 DE 69517768T2 DE 69517768 T DE69517768 T DE 69517768T DE 69517768 T DE69517768 T DE 69517768T DE 69517768 T2 DE69517768 T2 DE 69517768T2
- Authority
- DE
- Germany
- Prior art keywords
- imidazolylalkyl
- benzoxazin
- imidazo
- derivatives
- medicinal products
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9410469A GB9410469D0 (en) | 1994-05-25 | 1994-05-25 | Imidazolylalkyl derivatives of imidazo (5,1-c) (1,4) benzoxazin-1-one and process for their preparation |
PCT/EP1995/001650 WO1995032208A1 (en) | 1994-05-25 | 1995-05-02 | IMIDAZOLYLALKYL DERIVATIVES OF IMIDAZOL(5,1-c)(1,4)BENZOXAZIN-1-ONE AND THEIR USE AS THERAPEUTIC AGENTS |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69517768D1 DE69517768D1 (de) | 2000-08-10 |
DE69517768T2 true DE69517768T2 (de) | 2001-03-01 |
Family
ID=10755687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69517768T Expired - Fee Related DE69517768T2 (de) | 1994-05-25 | 1995-05-02 | IMIDAZOLYLALKYLDERIVATE VON IMIDAZO [5,1-c][1,4]BENZOXAZIN-1-ON UND IHRE VERWENDUNG ALS ARZNEIMITTEL |
Country Status (8)
Country | Link |
---|---|
US (1) | US5783574A (de) |
EP (1) | EP0711296B1 (de) |
JP (1) | JP3657985B2 (de) |
CA (1) | CA2166617A1 (de) |
DE (1) | DE69517768T2 (de) |
ES (1) | ES2149984T3 (de) |
GB (1) | GB9410469D0 (de) |
WO (1) | WO1995032208A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002092606A1 (fr) * | 2001-05-15 | 2002-11-21 | Takeda Chemical Industries, Ltd. | Derives d'imidazolidine fusionnes, leur procede de preparation et d'utilisation |
WO2007056362A2 (en) * | 2005-11-07 | 2007-05-18 | Indiana University Research And Technology Corporation | Glucagon analogs exhibiting physiological solubility and stability |
WO2009152289A1 (en) * | 2008-06-11 | 2009-12-17 | Indiana University Research And Technology Corporation | Methods for enhancing adsorption of molecules |
EA035469B1 (ru) * | 2013-03-15 | 2020-06-22 | Инсайт Холдингс Корпорейшн | Трициклические гетероциклы как ингибиторы белков бэт |
US9309246B2 (en) | 2013-12-19 | 2016-04-12 | Incyte Corporation | Tricyclic heterocycles as BET protein inhibitors |
MX2016013851A (es) | 2014-04-23 | 2017-07-14 | Incyte Corp | 1h-pirrolo[2,3-c]piridin-7(6h)-onas y pirazolo[3,4-c]piridin-7(6h) -onas como inhibidores de proteinas de bromodominio y extra terminal (bet). |
CR20220651A (es) | 2016-06-20 | 2023-01-23 | Incyte Corp | FORMAS SOLIDAS CRISTALINAS DE UN INHIBIDOR DE BET (Divisional expediente 2019-0027.) |
US11833155B2 (en) | 2020-06-03 | 2023-12-05 | Incyte Corporation | Combination therapy for treatment of myeloproliferative neoplasms |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1052009B (it) * | 1975-12-30 | 1981-06-20 | Erba Carlo Spa | Imidazo 4.3 c 1.4 benzossazino imidazo 4.3 c 1.4 benzotiazino pirazo 2.1 c 1.4 benzossazino e pirazo 2.1 c 1.4 benzotiazino derivati |
AU3443593A (en) * | 1992-02-13 | 1993-09-03 | Upjohn Company, The | 4-oxo- and 4H-imidazo(5,1-C)(1,4)benzoxazines useful as benzodiazepine receptor-binding agents |
GB9212486D0 (en) * | 1992-06-12 | 1992-07-22 | Erba Carlo Spa | Derivatives of substituted imidazo benzoxazin-1-one and process for their preparation |
-
1994
- 1994-05-25 GB GB9410469A patent/GB9410469D0/en active Pending
-
1995
- 1995-05-02 US US08/578,549 patent/US5783574A/en not_active Expired - Fee Related
- 1995-05-02 ES ES95917984T patent/ES2149984T3/es not_active Expired - Lifetime
- 1995-05-02 DE DE69517768T patent/DE69517768T2/de not_active Expired - Fee Related
- 1995-05-02 EP EP95917984A patent/EP0711296B1/de not_active Expired - Lifetime
- 1995-05-02 WO PCT/EP1995/001650 patent/WO1995032208A1/en active IP Right Grant
- 1995-05-02 CA CA002166617A patent/CA2166617A1/en not_active Abandoned
- 1995-05-02 JP JP53000895A patent/JP3657985B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0711296A1 (de) | 1996-05-15 |
WO1995032208A1 (en) | 1995-11-30 |
DE69517768D1 (de) | 2000-08-10 |
CA2166617A1 (en) | 1995-11-30 |
EP0711296B1 (de) | 2000-07-05 |
GB9410469D0 (en) | 1994-07-13 |
ES2149984T3 (es) | 2000-11-16 |
US5783574A (en) | 1998-07-21 |
JP3657985B2 (ja) | 2005-06-08 |
JPH09501954A (ja) | 1997-02-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE239712T1 (de) | Disubstituierte bicyclische heterocyclen, ihre herstellung und ihre verwendung als arzneimittel | |
DE3770085D1 (de) | Cyclodextrinclathrate von carbacyclinderivaten und ihre verwendung als arzneimittel. | |
DE59810448D1 (de) | Pyrazol-Derivate, ihre Herstellung und ihre Verwendung in Arzneimitteln | |
ATA71696A (de) | Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln | |
ATE299148T1 (de) | Substituierte isochinolin-3-carbonsäureamide, ihre herstellung und ihre verwendung als arzneimittel | |
DE10299001I2 (de) | Erythromycinderivate, ihre Verfahren zur Herstellung und ihre Verwendung als Arzneimittel | |
ATE401308T1 (de) | 4-aminopiperidin-derivate und ihre verwendung als arzneimittel | |
ATE224910T1 (de) | Derivate von dolestatin, deren herstellung und verwendung | |
ATE243708T1 (de) | Substituierte imidazolidinderivate, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate | |
ATE217633T1 (de) | Erythramicin-derivate, ihre verfahren zur herstellung und ihre verwendung als arzneimittel | |
EE9600172A (et) | Puriin-6-ooni derivaadid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja ravimid | |
ATE224363T1 (de) | Benzamidinderivate und ihre verwendung als arzneimittel mit ltb4-antagonistischer wirkung | |
ATE222236T1 (de) | Neue guanidinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
ATE215373T1 (de) | 21-hydro-6,19-oxidoprogesterone (21oh-60p) und deren verwendung als arzneimittel zur behandlung von glukokortikoidüberschuss | |
DE69726007D1 (de) | Prodrogs und analoga von camptothecin und deren verwendung als arzneimittel | |
ATE449786T1 (de) | Imidazolidinderivate, ihre herstellung, ihre verwendung und sie enthaltende pharmazeutische präparate | |
ZA952410B (en) | Substituted heterocyclic carboxamioesters their preparation and their use as pharmaceuticals | |
DE69517768T2 (de) | IMIDAZOLYLALKYLDERIVATE VON IMIDAZO [5,1-c][1,4]BENZOXAZIN-1-ON UND IHRE VERWENDUNG ALS ARZNEIMITTEL | |
DE69724453D1 (de) | Camptothecine analoga, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zubereitungen | |
ATE113600T1 (de) | Benzodiazepinverbindungen und ihre verwendung als arzneimittel. | |
ATE198192T1 (de) | Benzolsulfonamidderivate, ihre herstellung und ihre therapeutische verwendung | |
DE69517767T2 (de) | IMIDAZOLYLALKYLDERIVATE VON IMIDAZO[1,5-a]INDOL-3-ON UND IHRE VERWENDUNG ALS ARZNEIMITTEL | |
DE59609377D1 (de) | Kovalente lipid-phosphonocarbonsäure-konjugate und ihre anwendung als antivirale arzneimittel | |
DE69521347T2 (de) | Ketonitrilderivate, antibaktrielle mittel und sie enthaltende arzneimittel | |
DE59405814D1 (de) | Neue leukotrien-b4-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |