FI110097B - 5-(3-imidatso[4,5-b]pyridin-1-yyli-3-fenyyli-akryloyylioksi)-sykloheksaanikarboksyylihappojohdannaiset, niiden käyttö ja yhdisteitä sisältävät lääkeaineet - Google Patents

5-(3-imidatso[4,5-b]pyridin-1-yyli-3-fenyyli-akryloyylioksi)-sykloheksaanikarboksyylihappojohdannaiset, niiden käyttö ja yhdisteitä sisältävät lääkeaineet Download PDF

Info

Publication number
FI110097B
FI110097B FI952203A FI952203A FI110097B FI 110097 B FI110097 B FI 110097B FI 952203 A FI952203 A FI 952203A FI 952203 A FI952203 A FI 952203A FI 110097 B FI110097 B FI 110097B
Authority
FI
Finland
Prior art keywords
phenyl
eller
diabetes
imidazo
pyridin
Prior art date
Application number
FI952203A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI952203A (fi
FI952203A0 (fi
Inventor
Horst Hemmerle
Gerrit Schubert
Andreas Herling
Hans-Joerg Burger
Suad Efendic
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI952203A0 publication Critical patent/FI952203A0/fi
Publication of FI952203A publication Critical patent/FI952203A/fi
Application granted granted Critical
Publication of FI110097B publication Critical patent/FI110097B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI952203A 1994-05-10 1995-05-08 5-(3-imidatso[4,5-b]pyridin-1-yyli-3-fenyyli-akryloyylioksi)-sykloheksaanikarboksyylihappojohdannaiset, niiden käyttö ja yhdisteitä sisältävät lääkeaineet FI110097B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4416433 1994-05-10
DE4416433A DE4416433A1 (de) 1994-05-10 1994-05-10 Cyclohexan-Derivate, Verfahren zu ihrer Herstellung und die Verwendung der Verbindungen zur Behandlung von Krankheiten

Publications (3)

Publication Number Publication Date
FI952203A0 FI952203A0 (fi) 1995-05-08
FI952203A FI952203A (fi) 1995-11-11
FI110097B true FI110097B (fi) 2002-11-29

Family

ID=6517746

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952203A FI110097B (fi) 1994-05-10 1995-05-08 5-(3-imidatso[4,5-b]pyridin-1-yyli-3-fenyyli-akryloyylioksi)-sykloheksaanikarboksyylihappojohdannaiset, niiden käyttö ja yhdisteitä sisältävät lääkeaineet

Country Status (23)

Country Link
US (1) US5739147A (fr)
EP (1) EP0682024B1 (fr)
JP (1) JP3790564B2 (fr)
KR (1) KR100355690B1 (fr)
CN (1) CN1043643C (fr)
AT (1) ATE187454T1 (fr)
AU (1) AU683148B2 (fr)
CA (1) CA2149007C (fr)
CZ (1) CZ288443B6 (fr)
DE (2) DE4416433A1 (fr)
DK (1) DK0682024T3 (fr)
ES (1) ES2141276T3 (fr)
FI (1) FI110097B (fr)
GR (1) GR3032519T3 (fr)
HK (1) HK1011989A1 (fr)
HU (1) HU220865B1 (fr)
NO (1) NO304314B1 (fr)
NZ (1) NZ272082A (fr)
PL (1) PL180074B1 (fr)
RU (1) RU2140416C1 (fr)
TW (1) TW421648B (fr)
UA (1) UA41340C2 (fr)
ZA (1) ZA953726B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
DK1741447T3 (da) 2000-01-21 2013-12-09 Novartis Ag Kombinationer omfattende dipeptidylpeptidase-IV-inhibitorer og antidiabetiske midler
AU2002254940A1 (en) * 2001-03-12 2002-09-24 Novartis Pharma Gmbh Combination of nateglinide or repaglinide with at least one further antidiabetic compound
AU2006290908C1 (en) 2005-09-14 2014-04-03 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors for treating diabetes
WO2011041293A1 (fr) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Dérivés pyrazolo [1, 5—a] pyrimidines comme inhibiteurs de kinase 1 régulatrice de signal d'apoptose
JP5711270B2 (ja) 2010-02-03 2015-04-30 武田薬品工業株式会社 アポトーシスシグナル調節キナーゼ１阻害剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60243016A (ja) * 1984-05-17 1985-12-03 Tsumura Juntendo Inc 抗インフルエンザウイルス剤
TW255880B (fr) * 1992-09-09 1995-09-01 Hoechst Ag
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
DE4408082A1 (de) * 1994-03-10 1995-09-14 Hoechst Ag Substituierte Propan-Derivate, Verfahren zu ihrer Herstellung und die Anwendung der Verbindungen zur Behandlung von Krankheiten
DE4413402A1 (de) * 1994-04-18 1995-10-19 Hoechst Ag Verfahren zur Herstellung von Zwischenprodukten für die Synthese von Glucose-6-Phosphatase-Inhibitoren sowie neue Zwischenprodukte

Also Published As

Publication number Publication date
CA2149007C (fr) 2005-07-26
AU1792395A (en) 1995-11-16
CZ288443B6 (en) 2001-06-13
NZ272082A (en) 1996-09-25
KR100355690B1 (ko) 2002-12-26
NO951820L (no) 1995-11-13
AU683148B2 (en) 1997-10-30
PL180074B1 (pl) 2000-12-29
CA2149007A1 (fr) 1995-11-11
FI952203A (fi) 1995-11-11
DE4416433A1 (de) 1995-11-16
DK0682024T3 (da) 2000-05-22
UA41340C2 (uk) 2001-09-17
RU2140416C1 (ru) 1999-10-27
RU95107147A (ru) 1997-03-20
EP0682024B1 (fr) 1999-12-08
NO951820D0 (no) 1995-05-09
JP3790564B2 (ja) 2006-06-28
ZA953726B (en) 1996-01-11
CN1043643C (zh) 1999-06-16
US5739147A (en) 1998-04-14
NO304314B1 (no) 1998-11-30
EP0682024A1 (fr) 1995-11-15
PL308521A1 (en) 1995-11-13
ES2141276T3 (es) 2000-03-16
HUT71797A (en) 1996-02-28
DE59507361D1 (de) 2000-01-13
HU220865B1 (en) 2002-06-29
KR950032191A (ko) 1995-12-20
FI952203A0 (fi) 1995-05-08
HK1011989A1 (en) 1999-07-23
TW421648B (en) 2001-02-11
JPH07330767A (ja) 1995-12-19
GR3032519T3 (en) 2000-05-31
ATE187454T1 (de) 1999-12-15
CN1118782A (zh) 1996-03-20
CZ119595A3 (en) 1995-12-13

Similar Documents

Publication Publication Date Title
US4996206A (en) N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives
US5681959A (en) Chemical synthesis of azaindoles
FI103409B (fi) Menetelmä farmaseuttisesti käyttökelpoisten bentsimidatsolijohdannaist en valmistamiseksi
FI85482B (fi) Foerfarande foer framstaellning av nya terapeutiskt aktiva 9-/3-(4-guanidinofenyl) propylamino/oktahydro-10 oxo-6h-pyridazo/1,2-a//1,2/diazepin-1-karboxylsyraderivat.
FR2563521A1 (fr) Derives de la 1,4-dihydro-4-oxonaphtyridine et leurs sels, procede pour leur production et agents antibacteriens les contenant
FR2598709A1 (fr) Derives de l'acide quinoleinecarboxylique
JPH01500834A (ja) アザインドール及びインドリジン誘導体、その製造方法及び薬剤としてのその用途
MXPA04000159A (es) Compuestos heterociclicos 8/17 y usos de los mismos como inhibidores de ligasa d-alanil-d-alanina.
US4831030A (en) Diphenylpyridine compounds, processes for the preparation thereof and composition comprising the same
JP2002526542A (ja) Ｘａ因子阻害作用を有するイミダゾール［４，５−Ｃ−］−ピリジン−４−オン誘導体
FI110097B (fi) 5-(3-imidatso[4,5-b]pyridin-1-yyli-3-fenyyli-akryloyylioksi)-sykloheksaanikarboksyylihappojohdannaiset, niiden käyttö ja yhdisteitä sisältävät lääkeaineet
JPH03503889A (ja) ＰＡＦ拮抗剤としての１Ｈ／３Ｈ‐［４‐（Ｎ，Ｎ‐ジシクロアルキル／分枝アルキルカルボキサミド）‐ベンジル］イミダゾ［４，５‐ｃ］ピリジン類
US4320133A (en) Penicillins and their antibacterial use
FI88295C (fi) Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara 5-karbonylamino-4-hydroxi-n-hexanamidderivat
US5358956A (en) Fibrinogen receptor antagonists
EP0388298B1 (fr) Dérivés d'acides pyridone carboxyliques azétidinyl substitues, leur préparation et leur application en tant que médicaments
FR2933701A1 (fr) Derives anticancereux, leur preparation et leur application en therapeutique
PT88432B (pt) Processo para a preparacao de acidos 4-oxo-3-quinolinocarboxilicos uteis como agentes anti-bacterianos
US6013647A (en) Benzoxazinedione derivatives, method of producing them and uses thereof
EP0966466A1 (fr) DERIVES DE PYRROLO 3,2-c] QUINOLINE CONTENANT UN GROUPE HALOALCOXY ET LEURS SELS PHARMACEUTIQUEMENT ACCEPTABLES
JP2008528667A (ja) 化合物
FI77034C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla 4-oxo-4h-pyrimido/2,1-a/isokinolin-3- karboxylsyraderivat.
US4060527A (en) Pyrido[2,3-c]-acridine-1-hydroxy-2-carboxylic acid derivatives
ZA200505077B (en) Atropisomers of 3-substituted-4-arylquinolin-2-onederivatives
Jung et al. SYNTHESIS AND STRUCTURE-ACTIVITY RELATIONSHIPS OF NEW CEPHALOSPORINS WITH AMINOIMIDAZOLES AT C-7 EFFECT OF THE pKa OF THE C-7 AMINOIMIDAZOLE ON ANTIBACTERIAL SPECTRUM AND β-LACTAMASE STABILITY

Legal Events

Date Code Title Description
MA Patent expired