GR3032519T3 - Cyclohexane derivatives, processes for their preparation and their use as glucose-6-phosphatase inhibitors. - Google Patents

Cyclohexane derivatives, processes for their preparation and their use as glucose-6-phosphatase inhibitors.

Info

Publication number
GR3032519T3
GR3032519T3 GR20000400215T GR20000400215T GR3032519T3 GR 3032519 T3 GR3032519 T3 GR 3032519T3 GR 20000400215 T GR20000400215 T GR 20000400215T GR 20000400215 T GR20000400215 T GR 20000400215T GR 3032519 T3 GR3032519 T3 GR 3032519T3
Authority
GR
Greece
Prior art keywords
glucose
processes
preparation
phosphatase inhibitors
cyclohexane derivatives
Prior art date
Application number
GR20000400215T
Other languages
English (en)
Inventor
Horst Dr Hemmerle
Gerrit Dr Schubert
Hans-Joerg Dr Burger
Andreas Dr Herling
Suad Prof Dr Efendic
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of GR3032519T3 publication Critical patent/GR3032519T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
GR20000400215T 1994-05-10 2000-01-31 Cyclohexane derivatives, processes for their preparation and their use as glucose-6-phosphatase inhibitors. GR3032519T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4416433A DE4416433A1 (de) 1994-05-10 1994-05-10 Cyclohexan-Derivate, Verfahren zu ihrer Herstellung und die Verwendung der Verbindungen zur Behandlung von Krankheiten

Publications (1)

Publication Number Publication Date
GR3032519T3 true GR3032519T3 (en) 2000-05-31

Family

ID=6517746

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000400215T GR3032519T3 (en) 1994-05-10 2000-01-31 Cyclohexane derivatives, processes for their preparation and their use as glucose-6-phosphatase inhibitors.

Country Status (23)

Country Link
US (1) US5739147A (el)
EP (1) EP0682024B1 (el)
JP (1) JP3790564B2 (el)
KR (1) KR100355690B1 (el)
CN (1) CN1043643C (el)
AT (1) ATE187454T1 (el)
AU (1) AU683148B2 (el)
CA (1) CA2149007C (el)
CZ (1) CZ288443B6 (el)
DE (2) DE4416433A1 (el)
DK (1) DK0682024T3 (el)
ES (1) ES2141276T3 (el)
FI (1) FI110097B (el)
GR (1) GR3032519T3 (el)
HK (1) HK1011989A1 (el)
HU (1) HU220865B1 (el)
NO (1) NO304314B1 (el)
NZ (1) NZ272082A (el)
PL (1) PL180074B1 (el)
RU (1) RU2140416C1 (el)
TW (1) TW421648B (el)
UA (1) UA41340C2 (el)
ZA (1) ZA953726B (el)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW526202B (en) 1998-11-27 2003-04-01 Shionogi & Amp Co Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
ES2433476T3 (es) 2000-01-21 2013-12-11 Novartis Ag Combinaciones que contienen inhibidores de la dipeptidilpeptidasa-IV y agentes 5 antidiabéticos
EP1385549A2 (en) * 2001-03-12 2004-02-04 Novartis AG Combination of nateglinide or repaglinide with at least one further antidiabetic compound
PL1931350T5 (pl) 2005-09-14 2021-11-15 Takeda Pharmaceutical Company Limited Podanie inhibitorów dipeptydylo-peptydazy
WO2011041293A1 (en) 2009-09-30 2011-04-07 Takeda Pharmaceutical Company Limited Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
PT2531501E (pt) 2010-02-03 2014-02-17 Takeda Pharmaceutical Inibidores da cinase de regulação do sinal de apoptose 1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60243016A (ja) * 1984-05-17 1985-12-03 Tsumura Juntendo Inc 抗インフルエンザウイルス剤
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
TW255880B (el) * 1992-09-09 1995-09-01 Hoechst Ag
DE4408082A1 (de) * 1994-03-10 1995-09-14 Hoechst Ag Substituierte Propan-Derivate, Verfahren zu ihrer Herstellung und die Anwendung der Verbindungen zur Behandlung von Krankheiten
DE4413402A1 (de) * 1994-04-18 1995-10-19 Hoechst Ag Verfahren zur Herstellung von Zwischenprodukten für die Synthese von Glucose-6-Phosphatase-Inhibitoren sowie neue Zwischenprodukte

Also Published As

Publication number Publication date
FI110097B (fi) 2002-11-29
PL180074B1 (pl) 2000-12-29
AU683148B2 (en) 1997-10-30
RU2140416C1 (ru) 1999-10-27
HK1011989A1 (en) 1999-07-23
EP0682024A1 (de) 1995-11-15
RU95107147A (ru) 1997-03-20
HUT71797A (en) 1996-02-28
NZ272082A (en) 1996-09-25
HU220865B1 (en) 2002-06-29
ATE187454T1 (de) 1999-12-15
PL308521A1 (en) 1995-11-13
TW421648B (en) 2001-02-11
CZ288443B6 (en) 2001-06-13
CZ119595A3 (en) 1995-12-13
ZA953726B (en) 1996-01-11
CN1118782A (zh) 1996-03-20
NO951820L (no) 1995-11-13
AU1792395A (en) 1995-11-16
FI952203A (fi) 1995-11-11
NO951820D0 (no) 1995-05-09
ES2141276T3 (es) 2000-03-16
NO304314B1 (no) 1998-11-30
CN1043643C (zh) 1999-06-16
DE4416433A1 (de) 1995-11-16
DE59507361D1 (de) 2000-01-13
CA2149007C (en) 2005-07-26
US5739147A (en) 1998-04-14
KR950032191A (ko) 1995-12-20
EP0682024B1 (de) 1999-12-08
FI952203A0 (fi) 1995-05-08
KR100355690B1 (ko) 2002-12-26
UA41340C2 (uk) 2001-09-17
JPH07330767A (ja) 1995-12-19
CA2149007A1 (en) 1995-11-11
DK0682024T3 (da) 2000-05-22
JP3790564B2 (ja) 2006-06-28

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Legal Events

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