ES8801118A1 - Un metodo para preparar liposomas a base de un fosfolipeno un agente hidratante y un farmaco encapsulado. - Google Patents

Un metodo para preparar liposomas a base de un fosfolipeno un agente hidratante y un farmaco encapsulado.

Info

Publication number
ES8801118A1
ES8801118A1 ES556651A ES556651A ES8801118A1 ES 8801118 A1 ES8801118 A1 ES 8801118A1 ES 556651 A ES556651 A ES 556651A ES 556651 A ES556651 A ES 556651A ES 8801118 A1 ES8801118 A1 ES 8801118A1
Authority
ES
Spain
Prior art keywords
composition
making liposomes
preliposome
liposome
arginine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556651A
Other languages
English (en)
Other versions
ES556651A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allergan Inc
Original Assignee
Allergan Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25067952&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8801118(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergan Pharmaceuticals Inc filed Critical Allergan Pharmaceuticals Inc
Publication of ES8801118A1 publication Critical patent/ES8801118A1/es
Publication of ES556651A0 publication Critical patent/ES556651A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPOSICIONES FORMADORAS DE LIPOSOMAS. COMPRENDE: A) FORMAR UNA MEZCLA DE MATERIAL FOSFOLIPIDICO FORMADOR DE LIPOSOMAS ENTRE 20 Y 45JC; B) AÑADIR UN AGENTE HIDRATANTE EN LA MEZCLA Y EN UNA RELACION MOLAR ENTRE 1:20 Y 1:0,05 DE DICHO AGENTE HIDRATANTE RESPECTO AL MATERIAL FORMADOR DE LIPOSOMAS; C) AGREGAR A LA MEZCLA DE B) UN FARMACO QUE HA DE SER ENCAPSULADO; Y D) DISPERSAR LA MEZCLA DE C) EN UNA SOLUCION ACUOSA. EL AGENTE HIDRATANTE SE ELIGE ENTRE ARGININA, ASPARAFINA, LISINA Y OTROS Y EL MATERIAL FOSFOLIPIDICO FORMADOR DE LIPOSOMAS SE ELIGEN ENTRE GLICOLIPIDOS, ESFINGOLIPIDOS Y ACILGLICEROLES. SE UTILIZAN EN LA INDUSTRIA AGRICOLA, FARMACEUTICA O COSMETICA.
ES556651A 1985-08-07 1986-06-25 Un metodo para preparar liposomas a base de un fosfolipeno un agente hidratante y un farmaco encapsulado. Expired ES8801118A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76348485A 1985-08-07 1985-08-07

Publications (2)

Publication Number Publication Date
ES8801118A1 true ES8801118A1 (es) 1987-12-16
ES556651A0 ES556651A0 (es) 1987-12-16

Family

ID=25067952

Family Applications (1)

Application Number Title Priority Date Filing Date
ES556651A Expired ES8801118A1 (es) 1985-08-07 1986-06-25 Un metodo para preparar liposomas a base de un fosfolipeno un agente hidratante y un farmaco encapsulado.

Country Status (20)

Country Link
EP (1) EP0211647B1 (es)
JP (1) JP2511417B2 (es)
KR (1) KR900007185B1 (es)
CN (1) CN1027491C (es)
AT (1) ATE94754T1 (es)
AU (1) AU601154B2 (es)
CA (1) CA1280975C (es)
DE (1) DE3689056T2 (es)
DK (1) DK362786A (es)
ES (1) ES8801118A1 (es)
FI (1) FI863227A (es)
GR (1) GR862020B (es)
HK (1) HK1004530A1 (es)
HU (1) HU198836B (es)
IE (1) IE61445B1 (es)
IL (1) IL79114A (es)
NO (1) NO863176L (es)
NZ (1) NZ216768A (es)
PT (1) PT83130B (es)
ZA (1) ZA864541B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes
IT1214540B (it) * 1986-10-23 1990-01-18 Vincenzo Zappia Mario De Rosa Formulazioni idrosolubili di ubidecarenoni, procedimento per laloro preparazione e composizioni farmaceutiche che li compongono.
JPH01501153A (ja) * 1986-10-23 1989-04-20 アルバル・エッセ・ピ・ア ユビデカレノン類を含有する化粧品
EP0382777B1 (en) * 1987-10-19 1994-10-12 The Liposome Company, Inc. Aqueous preparation of liposome composition
FR2631234B1 (fr) * 1988-05-10 1990-09-14 Dior Christian Parfums Composition cosmetique ou dermatologique, notamment a action amincissante ou anti-cellulitique contenant des extraits de cola sous forme libre ou sous forme liposomale
JP2786482B2 (ja) * 1988-06-29 1998-08-13 第一製薬株式会社 脂質膜構造体
BE1001869A3 (fr) * 1988-10-12 1990-04-03 Franz Legros Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine.
US5741513A (en) * 1990-02-08 1998-04-21 A. Natterman & Cie. Gmbh Alcoholic aqueous gel-like phospholipid composition, its use and topical preparations containing it
JP3218637B2 (ja) * 1990-07-26 2001-10-15 大正製薬株式会社 安定なリポソーム水懸濁液
JP3765579B2 (ja) * 1990-08-24 2006-04-12 イーデーエーアー アーゲー 作用物質投与用超微小滴状調剤
US6165500A (en) * 1990-08-24 2000-12-26 Idea Ag Preparation for the application of agents in mini-droplets
DE4038075C1 (en) * 1990-11-29 1992-03-19 B. Braun Melsungen Ag, 3508 Melsungen, De Encapsulating solid or liq. lipophilic agents - comprises mixing hydration medium with phospholipid increasing temp. to above soln. phase change temp. and adding remaining medium
CA2087691A1 (en) * 1992-01-23 1993-07-24 Peter Critchley Cosmetic compositon
GB9224502D0 (en) * 1992-11-23 1993-01-13 New Roger R C Method of preparing a lipid-containing formulation
WO1994019013A1 (en) * 1993-02-19 1994-09-01 Smithkline Beecham Corporation Influenza vaccine compositions containing 3-o-deacylated monophosphoryl lipid a
SG65599A1 (en) * 1993-03-24 1999-06-22 Collaborative Lab Inc Cosmetic delivery system for salicylic acid and process for preparation of same
CA2120197A1 (en) * 1993-04-02 1994-10-03 Kenji Endo Stable aqueous dispersions containing liposomes
JPH0757826A (ja) * 1993-08-18 1995-03-03 Nec Corp 端子台
US6375980B1 (en) * 1998-01-08 2002-04-23 Research Development Foundation Stabilization of lipid:DNA formulations during nebulization
TW520294B (en) * 1998-01-08 2003-02-11 Res Dev Foundation Stabilization of lipid: DNA formulations during nebulization
DE69825495T2 (de) 1998-12-23 2005-07-28 Idea Ag Verbesserte formulierung zur topischen, nichtinvasiven anwendung in vivo
ATE216223T1 (de) 1999-01-27 2002-05-15 Idea Ag Transnasaler transport bzw. impfung mit hochadaptierbaren trägern
ATE216875T1 (de) 1999-01-27 2002-05-15 Idea Ag Nichtinvasive impfung durch die haut
US6248353B1 (en) * 1999-12-10 2001-06-19 Dade Behring Inc. Reconstitution of purified membrane proteins into preformed liposomes
EP1138310A1 (de) * 2000-03-28 2001-10-04 Primacare S.A. Pro-liposomen
ATE319428T1 (de) 2000-12-07 2006-03-15 Univ Utrecht Holding Bv Zusammensetzung zur behandlung von entzündlichen erkrankungen
US6610322B1 (en) 2000-12-20 2003-08-26 Brian Charles Keller Self forming, thermodynamically stable liposomes and their applications
GB0404993D0 (en) * 2004-03-05 2004-04-07 Univ Liverpool John Moores Method and apparatus for producing carrier complexes
MX2007012121A (es) * 2005-03-31 2007-11-20 Unilever Nv Entrega intensificada de agentes de beneficio para la piel.
PL2081551T3 (pl) * 2006-10-06 2013-06-28 Scil Tech Gmbh Wytworzenie wysuszonego rekonstytuowanego pęcherzyka do zastosowania farmaceutycznego
JP5112673B2 (ja) * 2006-10-16 2013-01-09 株式会社コーセー セラミド含有組成物及びこれを配合する皮膚外用剤
CN103327965B (zh) 2011-01-25 2017-07-18 宝洁公司 脂质体和包含脂质体的个人护理组合物
US10159646B2 (en) * 2013-08-12 2018-12-25 Altum-Avro Pharma Partnership Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery
US8986732B2 (en) 2013-08-12 2015-03-24 Helix Biopharma Corporation Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery
IT201700086879A1 (it) * 2017-07-28 2019-01-28 Univ Degli Studi Cagliari Vescicole lipidiche a doppio strato contenenti adrenalina, per uso nel trattamento delle emergenze cardiache
CN109224879B (zh) * 2018-09-17 2021-04-27 南京工业大学 一种cha分子筛膜的制备方法
CN113995852B (zh) * 2021-11-08 2024-01-30 河北大学 Arg-脂质体微囊、微囊包封的鱼精蛋白-siRNA复合体及其制备方法和应用

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK116528A (es) * 1966-09-30
US3932657A (en) * 1973-11-12 1976-01-13 The United States Of America As Represented By The United States Energy Research And Development Administration Liposome encapsulation of chelating agents
US3957971A (en) * 1974-07-29 1976-05-18 Lever Brothers Company Moisturizing units and moisturizing compositions containing the same
AT356278B (de) * 1976-07-12 1980-04-25 Hoffmann La Roche Verfahren zur herstellung von injektions- loesungen
JPS5323872A (en) * 1976-08-17 1978-03-04 Takeda Chem Ind Ltd Preparation of microcapsule
DE2656333C2 (de) * 1976-12-13 1985-08-08 Karl Prof. Dr.med. 7302 Ostfildern Theurer Verfahren zur Herstellung von Liposomen, welche Arzneistoffe enthalten
IT1110989B (it) * 1979-01-19 1986-01-13 Erba Farmitalia Forme farmaceutiche costitutite da liposomi e procedimenti relativi
DE2856333C2 (de) * 1978-12-27 1983-09-22 A. Nattermann & Cie GmbH, 5000 Köln Oral einnehmbare Arzneimittel mit entzündungshemmender Wirkung
US4174296A (en) * 1978-12-04 1979-11-13 American Lecithin Company Water soluble lecithin composition
US4528193A (en) * 1978-12-27 1985-07-09 A. Natterman & Cie. Gmbh Inflammation-preventing pharmaceutical composition of oral administration
DE2914789A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Injizierbare arzneimittel mit entzuendungshemmender wirkung
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
JPS574913A (en) * 1980-06-11 1982-01-11 Green Cross Corp:The Urokinase preparation for oral administration
JPS5746921A (en) * 1980-09-02 1982-03-17 Green Cross Corp:The Oral preparation of human blood coagulation factor
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
AU564876B2 (en) * 1982-03-29 1987-08-27 Liposome Company, Inc., The Stable plurilamellar vesicles
EP0102324A3 (de) * 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
SE8206744D0 (sv) * 1982-11-26 1982-11-26 Fluidcarbon International Ab Preparat for kontrollerad avgivning av substanser
FR2540381B1 (fr) * 1983-02-08 1986-05-30 Dior Sa Parfums Christian Procede pour stimuler la croissance des cellules; composition cosmetique, pharmaceutique et composition complementaire pour milieu de culture cellulaire appliquant ce procede
JPS607932A (ja) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソーム懸濁液およびその製法
JPS607934A (ja) * 1983-06-29 1985-01-16 Dai Ichi Seiyaku Co Ltd リポソ−ムの製造方法
IL79114A (en) * 1985-08-07 1990-09-17 Allergan Pharma Method and composition for making liposomes

Also Published As

Publication number Publication date
HUT43487A (en) 1987-11-30
DE3689056D1 (de) 1993-10-28
AU601154B2 (en) 1990-09-06
ES556651A0 (es) 1987-12-16
DK362786D0 (da) 1986-07-30
AU5914186A (en) 1987-12-24
NZ216768A (en) 1989-11-28
IL79114A0 (en) 1986-09-30
IE862103L (en) 1987-02-07
EP0211647B1 (en) 1993-09-22
KR880002508A (ko) 1988-05-09
IE61445B1 (en) 1994-11-02
IL79114A (en) 1990-09-17
NO863176D0 (no) 1986-08-06
FI863227A0 (fi) 1986-08-06
JPS6242733A (ja) 1987-02-24
CN1027491C (zh) 1995-01-25
PT83130B (pt) 1989-03-30
KR900007185B1 (ko) 1990-09-29
PT83130A (en) 1986-09-01
DK362786A (da) 1987-02-08
HK1004530A1 (en) 1998-11-27
GR862020B (en) 1986-12-24
CA1280975C (en) 1991-03-05
ZA864541B (en) 1987-02-25
EP0211647A1 (en) 1987-02-25
JP2511417B2 (ja) 1996-06-26
NO863176L (no) 1987-02-09
ATE94754T1 (de) 1993-10-15
CN86104874A (zh) 1987-02-04
HU198836B (en) 1989-12-28
FI863227A (fi) 1987-02-08
DE3689056T2 (de) 1994-01-27

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