ES8606323A1 - Un procedimiento para preparar una sal de acido n-acetil- neuraminico - Google Patents
Un procedimiento para preparar una sal de acido n-acetil- neuraminicoInfo
- Publication number
- ES8606323A1 ES8606323A1 ES546840A ES546840A ES8606323A1 ES 8606323 A1 ES8606323 A1 ES 8606323A1 ES 546840 A ES546840 A ES 546840A ES 546840 A ES546840 A ES 546840A ES 8606323 A1 ES8606323 A1 ES 8606323A1
- Authority
- ES
- Spain
- Prior art keywords
- acetylneuraminic acid
- expectorants
- salts
- expectorant
- sputum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003172 expectorant agent Substances 0.000 title abstract 3
- 230000003419 expectorant effect Effects 0.000 title abstract 3
- SQVRNKJHWKZAKO-PFQGKNLYSA-N N-acetyl-beta-neuraminic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)O[C@H]1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-PFQGKNLYSA-N 0.000 title abstract 2
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 title abstract 2
- 229940066493 expectorants Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- 206010036790 Productive cough Diseases 0.000 abstract 1
- 230000001886 ciliary effect Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 210000003802 sputum Anatomy 0.000 abstract 1
- 208000024794 sputum Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59189950A JPS6168418A (ja) | 1984-09-11 | 1984-09-11 | 去痰薬 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES546840A0 ES546840A0 (es) | 1986-04-16 |
| ES8606323A1 true ES8606323A1 (es) | 1986-04-16 |
Family
ID=16249907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES546840A Expired ES8606323A1 (es) | 1984-09-11 | 1985-09-10 | Un procedimiento para preparar una sal de acido n-acetil- neuraminico |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4698332A (cg-RX-API-DMAC7.html) |
| EP (2) | EP0429430B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPS6168418A (cg-RX-API-DMAC7.html) |
| KR (1) | KR880001234B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN85108388B (cg-RX-API-DMAC7.html) |
| AT (2) | ATE111738T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU582584B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA1246452A (cg-RX-API-DMAC7.html) |
| DE (2) | DE3587587T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK165046C (cg-RX-API-DMAC7.html) |
| ES (1) | ES8606323A1 (cg-RX-API-DMAC7.html) |
| FI (1) | FI83963C (cg-RX-API-DMAC7.html) |
| HU (2) | HU197515B (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA856905B (cg-RX-API-DMAC7.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61289037A (ja) * | 1985-06-14 | 1986-12-19 | Mect Corp | 新規去痰薬 |
| GB8519416D0 (en) * | 1985-08-01 | 1985-09-04 | Unilever Plc | Oligosaccharides |
| JP2573594B2 (ja) * | 1987-03-06 | 1997-01-22 | メクト株式会社 | Ｎーアセチルー３ーフルオローノイラミン酸誘導体およびその製造方法 |
| US5843445A (en) * | 1987-06-24 | 1998-12-01 | Autoimmune, Inc. | Method of treating rheumatoid arthritis with type II collagen |
| JP2517293B2 (ja) * | 1987-06-25 | 1996-07-24 | メクト株式会社 | 細胞、組織修復剤 |
| US5393742A (en) * | 1990-08-30 | 1995-02-28 | Mect Corporation | Preparation for treating renal disease |
| US5514665A (en) * | 1993-12-30 | 1996-05-07 | University Of British Columbia | Method of preventing or reducing the risk of infection by bacterial pathogens utilizing simple and conjugated dextrans |
| AUPM411494A0 (en) * | 1994-02-25 | 1994-03-24 | Central Sydney Area Health Service | Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum |
| US5856446A (en) * | 1995-07-07 | 1999-01-05 | Autoimmune Inc. | Method of treating rheumatoid arthritis with low dose type II collagen |
| AUPQ275799A0 (en) | 1999-09-10 | 1999-10-07 | Luminis Pty Limited | Recombinant bacterium expressing an oligosaccharide receptor mimic |
| JP4005115B1 (ja) | 2007-02-08 | 2007-11-07 | 日本臓器製薬株式会社 | 疼痛疾患治療剤 |
| US9241896B2 (en) * | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| UA110325C2 (en) | 2009-07-03 | 2015-12-25 | Australian Biomedical Company Pty Ltd | Medicinal carbohydrates for treating respiratory conditions |
| KR20140003380A (ko) | 2010-07-13 | 2014-01-09 | 울트라제닉스 파마수티컬 인코포레이티드 | 시알산 결함 치료용 방법들 및 제형들 |
| HK1201067A1 (en) | 2011-10-24 | 2015-08-21 | 罕见病药物研发公司 | Sialic acid analogs |
| EP3001837A4 (en) | 2013-03-15 | 2017-05-17 | Huiru Wang | Biological therapeutics for infection-relating disorders or conditions |
| EP3620165A1 (en) | 2013-03-15 | 2020-03-11 | B&H Biotechnologies, LLC | Compositions for use in the treatment of infectious or inflammatory diseases |
| CN106573950B (zh) * | 2014-07-30 | 2020-09-15 | 协和发酵生化株式会社 | N-乙酰神经氨酸碱金属盐无水物的晶体及其制造方法 |
| KR102646509B1 (ko) * | 2015-01-28 | 2024-03-11 | 교와 핫꼬 바이오 가부시키가이샤 | N-아세틸노이라민산암모늄염·무수화물의 결정 및 그 제조 방법 |
| AR106025A1 (es) | 2015-09-14 | 2017-12-06 | Ultragenyx Pharmaceutical Inc | Formas cristalinas de ácido siálico o una sal o solvato de este |
| CN109771316B (zh) * | 2018-12-29 | 2022-02-25 | 中国科学院合肥物质科学研究院 | 一种提高n-乙酰神经氨酸水溶液稳定性的方法及其应用 |
| CN110606864B (zh) * | 2019-10-08 | 2023-10-10 | 中国科学院合肥物质科学研究院 | 一种n-乙酰神经氨酸钙盐晶体及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1199116B (it) * | 1984-07-03 | 1988-12-30 | Fidia Farmaceutici | Derivati di gangliosidi |
| IT1177863B (it) * | 1984-07-03 | 1987-08-26 | Fidia Farmaceutici | Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche |
| IT1182209B (it) * | 1985-02-18 | 1987-09-30 | Fidia Farmaceutici | Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali |
-
1984
- 1984-09-11 JP JP59189950A patent/JPS6168418A/ja active Granted
-
1985
- 1985-09-06 US US06/773,036 patent/US4698332A/en not_active Expired - Fee Related
- 1985-09-10 FI FI853456A patent/FI83963C/fi not_active IP Right Cessation
- 1985-09-10 ES ES546840A patent/ES8606323A1/es not_active Expired
- 1985-09-10 DE DE91100080T patent/DE3587587T2/de not_active Expired - Fee Related
- 1985-09-10 ZA ZA856905A patent/ZA856905B/xx unknown
- 1985-09-10 AT AT85111414T patent/ATE111738T1/de not_active IP Right Cessation
- 1985-09-10 EP EP91100080A patent/EP0429430B1/en not_active Expired - Lifetime
- 1985-09-10 CA CA000490308A patent/CA1246452A/en not_active Expired
- 1985-09-10 EP EP85111414A patent/EP0177783B1/en not_active Expired - Lifetime
- 1985-09-10 HU HU853417A patent/HU197515B/hu not_active IP Right Cessation
- 1985-09-10 KR KR1019850006606A patent/KR880001234B1/ko not_active Expired
- 1985-09-10 AU AU47199/85A patent/AU582584B2/en not_active Ceased
- 1985-09-10 DE DE3587928T patent/DE3587928T2/de not_active Expired - Fee Related
- 1985-09-10 HU HU883140A patent/HU198733B/hu unknown
- 1985-09-10 AT AT91100080T patent/ATE94396T1/de not_active IP Right Cessation
- 1985-09-11 DK DK413785A patent/DK165046C/da not_active IP Right Cessation
- 1985-11-15 CN CN85108388A patent/CN85108388B/zh not_active Expired
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20010301 |