ES8603579A1 - Un procedimiento para producir un vector de transferencia de adn. - Google Patents
Un procedimiento para producir un vector de transferencia de adn.Info
- Publication number
- ES8603579A1 ES8603579A1 ES524885A ES524885A ES8603579A1 ES 8603579 A1 ES8603579 A1 ES 8603579A1 ES 524885 A ES524885 A ES 524885A ES 524885 A ES524885 A ES 524885A ES 8603579 A1 ES8603579 A1 ES 8603579A1
- Authority
- ES
- Spain
- Prior art keywords
- characterization
- molecular cloning
- gene sequence
- sequence coding
- human relaxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/64—Relaxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/30—Signal or leader sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
PROCEDIMIENTO PARA PRODUCIR UN VECTOR DE TRANSFERENCIA DE ADN. CONSISTE EN HACER REACCIONAR LA SECUENCIA DE DESOXINUCLEOTIDOS APROPIADA DE PREPRORRELAXINA HUMANA O LA SUB-UNIDAD, EQUIVALENTE O DERIVADO, CON UNA MOLECULA DE ADN DERIVADA DE UN VECTOR DE TRANSFERENCIA ESCINDIDO CON UNA ENZIMA DE RESTRICCION, DONDE LA SECUENCIA DE DESOXINUCLEOTIDOS COMPRENDE UNA CADENA CODIFICADORA Y UNA CADENA COMPLEMENTARIA QUE CORRESPONDEN A UNA SECUENCIA DE ARNM COMPLETA, DONDE LA SUB-UNIDAD ES LA SECUENCIA DE DESOXINUCLEOTIDOS QUE CODIFICA PRORRELAXINA HUMANA Y DONDE UNO O MAS DE LOS CODONES NATURALES DE LA SECUENCIA DE PREPRORRELAXINA HUMANA O SUS EQUIVALENTES DE ADN COMPLEMENTARIO ESTAN REEMPLAZADOS POR OTRO CODON QUE CODIFICA EL MISMO O UN DIFERENTE AMINOACIDO Y/O UNO O MAS DE DICHOS CODONES ESTAN SUPRIMIDOS Y/O UNO O MAS CODONES ADICIONALES ESTAN AÑADIDOS A LA SECUENCIA NATURAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPF535282 | 1982-08-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES524885A0 ES524885A0 (es) | 1985-12-16 |
ES8603579A1 true ES8603579A1 (es) | 1985-12-16 |
Family
ID=3769689
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES524885A Expired ES8603579A1 (es) | 1982-08-12 | 1983-08-11 | Un procedimiento para producir un vector de transferencia de adn. |
ES540886A Expired ES8802160A1 (es) | 1982-08-12 | 1985-03-01 | Un procedimiento para aislar un gen de relaxina cromosomica de un ser humano o de otro primate o una especie afin |
ES550943A Expired ES8802394A1 (es) | 1982-08-12 | 1986-01-16 | Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana. |
ES557506A Expired ES8801671A1 (es) | 1982-08-12 | 1987-04-15 | Un procedimiento para preparar relaxina humana o sus analogos |
ES557505A Expired ES8801676A1 (es) | 1982-08-12 | 1987-04-15 | Un procedimiento para preparar relaxina humana o sus analogos |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES540886A Expired ES8802160A1 (es) | 1982-08-12 | 1985-03-01 | Un procedimiento para aislar un gen de relaxina cromosomica de un ser humano o de otro primate o una especie afin |
ES550943A Expired ES8802394A1 (es) | 1982-08-12 | 1986-01-16 | Un procedimiento para preparar una proteina de fusion derivada de la secuencia de aminoacidos de la preprorrelaxina humana. |
ES557506A Expired ES8801671A1 (es) | 1982-08-12 | 1987-04-15 | Un procedimiento para preparar relaxina humana o sus analogos |
ES557505A Expired ES8801676A1 (es) | 1982-08-12 | 1987-04-15 | Un procedimiento para preparar relaxina humana o sus analogos |
Country Status (14)
Country | Link |
---|---|
US (1) | US4871670A (es) |
EP (2) | EP0287820B1 (es) |
JP (3) | JP2537477B2 (es) |
KR (1) | KR930003515B1 (es) |
AT (1) | ATE78042T1 (es) |
CA (1) | CA1340542C (es) |
DE (1) | DE3382117D1 (es) |
DK (2) | DK171827B1 (es) |
ES (5) | ES8603579A1 (es) |
HU (1) | HU197350B (es) |
IE (1) | IE58682B1 (es) |
IL (1) | IL69469A (es) |
NZ (1) | NZ205241A (es) |
ZA (1) | ZA835963B (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5320953A (en) * | 1982-08-12 | 1994-06-14 | Howard Florey Institute Of Experimental Physiology And Medicine | Process for synthesizing human H1-prorelaxin, H1-relaxin and fusion proteins thereof |
US5023321A (en) * | 1982-12-13 | 1991-06-11 | Howard Florey Institute Of Experimental Physiology & Medicine | Molecular cloning and characterization of a further gene sequence coding for human relaxin |
IL70414A (en) * | 1982-12-13 | 1991-06-10 | Florey Howard Inst | Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors |
US4835251A (en) * | 1986-06-23 | 1989-05-30 | Genetech, Inc. | Method of chain combination |
JP2815649B2 (ja) * | 1988-02-26 | 1998-10-27 | ジェネンテク,インコーポレイテッド | ヒトレラキシン製剤 |
EP0470976B1 (en) * | 1989-05-04 | 1993-03-31 | Genentech, Inc. | Processes and compositions for the isolation of human relaxin |
US5089419A (en) * | 1989-08-07 | 1992-02-18 | International Canine Genetics | Detection of pregnancy by identification of the c peptide of relaxin in the urine of animals |
US5166191A (en) * | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
US5478807A (en) * | 1991-08-19 | 1995-12-26 | Genentech, Inc. | Use of relaxin in the treatment of bradycardia |
US6348327B1 (en) * | 1991-12-06 | 2002-02-19 | Genentech, Inc. | Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells |
EP0707650B1 (en) * | 1993-06-21 | 2003-05-21 | Genentech, Inc. | Process for producing human relaxin |
US5911997A (en) * | 1995-06-07 | 1999-06-15 | Connetics Corporation | Relaxin-like factor and methods and uses thereof |
AU2002256359A1 (en) * | 2001-04-24 | 2002-11-05 | Epigenesis Pharmaceuticals, Inc. | Antisense and anti-inflammatory based compositions to treat respiratory disorders |
AU2002324727A1 (en) * | 2001-08-17 | 2003-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Mammalian relaxin receptors |
AU2003903124A0 (en) * | 2003-06-20 | 2003-07-10 | Mark Del Borgo | Analogues of heteromeric proteins |
JP4836942B2 (ja) * | 2004-04-30 | 2011-12-14 | コーセラ, インコーポレイテッド | リラキシンの調節による胎仔の発育の制御のための方法および組成物 |
US20060052304A1 (en) * | 2004-09-02 | 2006-03-09 | Bas Medical, Inc. | Method for remodeling bone and related sutures |
US8389475B2 (en) * | 2009-08-10 | 2013-03-05 | The Board Of Trustees Of The Leland Stanford Junior University | Relaxin analogs |
CA2808596C (en) * | 2010-08-17 | 2020-12-15 | Ambrx, Inc. | Modified relaxin polypeptides and their uses |
EP2652491B1 (en) * | 2010-12-15 | 2017-11-29 | Baxalta GmbH | Eluate collection using conductivity gradient |
EP2630964A1 (en) | 2012-02-22 | 2013-08-28 | Immundiagnostik AG | Method and medicament for treating patients in risk of prediabetes and type-2 diabetes |
EP3068891A1 (en) | 2013-11-13 | 2016-09-21 | Aequus Biopharma Inc. | Engineered glycoproteins and uses thereof |
EP2946788A1 (en) | 2014-05-23 | 2015-11-25 | Immundiagnostik AG | Method and composition for treating heart failure with preserved ejection fraction |
WO2017201340A2 (en) | 2016-05-18 | 2017-11-23 | Modernatx, Inc. | Polynucleotides encoding relaxin |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4267101A (en) * | 1980-02-01 | 1981-05-12 | Serono Laboratories Inc. | Process for obtaining human relaxin from fetal membranes |
IE55479B1 (en) * | 1982-02-12 | 1990-09-26 | Florey Howard Inst | Molecular cloning and characterization of the gene sequence coding for porcine relaxin |
IL70414A (en) * | 1982-12-13 | 1991-06-10 | Florey Howard Inst | Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors |
-
1983
- 1983-08-11 EP EP88104503A patent/EP0287820B1/en not_active Expired - Lifetime
- 1983-08-11 EP EP83304662A patent/EP0101309B1/en not_active Expired - Lifetime
- 1983-08-11 IL IL69469A patent/IL69469A/xx not_active IP Right Cessation
- 1983-08-11 DE DE8383304662T patent/DE3382117D1/de not_active Expired - Lifetime
- 1983-08-11 DK DK366483A patent/DK171827B1/da not_active IP Right Cessation
- 1983-08-11 AT AT88104503T patent/ATE78042T1/de not_active IP Right Cessation
- 1983-08-11 ES ES524885A patent/ES8603579A1/es not_active Expired
- 1983-08-12 JP JP58146766A patent/JP2537477B2/ja not_active Expired - Lifetime
- 1983-08-12 ZA ZA835963A patent/ZA835963B/xx unknown
- 1983-08-12 CA CA000434438A patent/CA1340542C/en not_active Expired - Fee Related
- 1983-08-12 HU HU832842A patent/HU197350B/hu unknown
- 1983-08-12 NZ NZ205241A patent/NZ205241A/xx unknown
- 1983-08-12 IE IE190983A patent/IE58682B1/en not_active IP Right Cessation
- 1983-08-12 KR KR1019830003783A patent/KR930003515B1/ko not_active IP Right Cessation
-
1985
- 1985-03-01 ES ES540886A patent/ES8802160A1/es not_active Expired
-
1986
- 1986-01-16 ES ES550943A patent/ES8802394A1/es not_active Expired
- 1986-05-12 US US06/863,819 patent/US4871670A/en not_active Expired - Lifetime
-
1987
- 1987-04-15 ES ES557506A patent/ES8801671A1/es not_active Expired
- 1987-04-15 ES ES557505A patent/ES8801676A1/es not_active Expired
-
1992
- 1992-12-28 DK DK156592A patent/DK171683B1/da not_active IP Right Cessation
-
1993
- 1993-03-19 JP JP5060138A patent/JP2670001B2/ja not_active Expired - Lifetime
-
1995
- 1995-01-05 JP JP7000236A patent/JP2892596B2/ja not_active Expired - Lifetime
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000601 |