ES8506706A1 - Procedimiento para la obtencion de esteres sustituidos de tiazolidimilos de acidos minerales. - Google Patents

Procedimiento para la obtencion de esteres sustituidos de tiazolidimilos de acidos minerales.

Info

Publication number
ES8506706A1
ES8506706A1 ES516888A ES516888A ES8506706A1 ES 8506706 A1 ES8506706 A1 ES 8506706A1 ES 516888 A ES516888 A ES 516888A ES 516888 A ES516888 A ES 516888A ES 8506706 A1 ES8506706 A1 ES 8506706A1
Authority
ES
Spain
Prior art keywords
mineral acids
esters
thiazolidinylic
substituted
rest
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516888A
Other languages
English (en)
Other versions
ES516888A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8506706A1 publication Critical patent/ES8506706A1/es
Publication of ES516888A0 publication Critical patent/ES516888A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ESTERES SUSTITUIDOS DE TIAZOLIDINILO DE ACIDOS MINERALES, QUE RESPONDEN A LA FORMULA GENERAL (I), EN LA QUE R1 Y R2 SIGNIFICAN UN RESTO ALQUILO INSATURADO EN LA POSICION 2,3, CON 3 O 4 ATOMOS DE CARBONO; R3 Y R4, INDEPENDIENTEMENTE ENTRE SI, SIGNIFICAN HIDROGENO O METILO; Y A SIGNIFICA UN RESTO DE FORMULA (II), Y SUS SALES.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (III), CON UN COMPUESTO INTRODUCTOR DEL RESTO DE LA FORMULA PARCIAL (II). LA MEZCLA DE ISOMEROS OBTENIDA SE PUEDE SEPARAR EN LOS DIVERSOS ISOMEROS.DE APLICACION EN MEDICINA POR SU EFICACIA INHIBIDORA DE LOS TUMORES.
ES516888A 1982-01-22 1982-10-27 Procedimiento para la obtencion de esteres sustituidos de tiazolidimilos de acidos minerales. Granted ES516888A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH40682 1982-01-22

Publications (2)

Publication Number Publication Date
ES8506706A1 true ES8506706A1 (es) 1985-07-16
ES516888A0 ES516888A0 (es) 1985-07-16

Family

ID=4186307

Family Applications (3)

Application Number Title Priority Date Filing Date
ES516888A Granted ES516888A0 (es) 1982-01-22 1982-10-27 Procedimiento para la obtencion de esteres sustituidos de tiazolidimilos de acidos minerales.
ES529335A Expired ES8605512A1 (es) 1982-01-22 1984-01-31 Procedimiento para la obtencion de esteres sustituidos de tiazolidinilo de acidos minerales
ES535201A Granted ES535201A0 (es) 1982-01-22 1984-08-16 Procedimiento para la obtencion deesteres sustituidos de tiazolidinilo de acidos minerales

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES529335A Expired ES8605512A1 (es) 1982-01-22 1984-01-31 Procedimiento para la obtencion de esteres sustituidos de tiazolidinilo de acidos minerales
ES535201A Granted ES535201A0 (es) 1982-01-22 1984-08-16 Procedimiento para la obtencion deesteres sustituidos de tiazolidinilo de acidos minerales

Country Status (24)

Country Link
US (1) US4489069A (es)
EP (1) EP0085275B1 (es)
JP (1) JPS58135871A (es)
KR (1) KR880001716B1 (es)
AT (1) ATE18044T1 (es)
AU (1) AU555533B2 (es)
CS (1) CS241514B2 (es)
DD (1) DD203909A5 (es)
DE (1) DE3269209D1 (es)
DK (1) DK451282A (es)
ES (3) ES516888A0 (es)
FI (1) FI823458A0 (es)
GB (1) GB2122604B (es)
GR (1) GR77024B (es)
HU (1) HU188214B (es)
IL (1) IL67023A (es)
NO (1) NO823445L (es)
NZ (1) NZ202179A (es)
PH (1) PH20238A (es)
PL (2) PL137949B1 (es)
PT (1) PT75704B (es)
RO (2) RO87991A (es)
SU (3) SU1181545A3 (es)
ZA (1) ZA827444B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582841A (en) * 1983-07-19 1986-04-15 Ciba-Geigy Corporation Substituted thiazolidinyl esters of mineral acids
EP0224515A1 (de) * 1985-06-10 1987-06-10 Ciba-Geigy Ag Substituierte thiazolidinylether
ZA868951B (en) * 1985-12-07 1987-08-26 Shionogi & Company Limited Organophosphorus compounds having pesticidal activity
US5177091A (en) * 1990-12-06 1993-01-05 Ciba-Geigy Corporation Use of carbazones as novel active ingredients in medicaments
AU658175B2 (en) * 1991-04-12 1995-04-06 Novartis Ag Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
AU665073B2 (en) * 1992-06-03 1995-12-14 Ciba-Geigy Ag Novel thiosemicarbazone derivatives
AU2109695A (en) 1994-03-30 1995-10-23 Novartis Ag Screening method using the rzr receptor family

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3699116A (en) * 1965-10-29 1972-10-17 Ciba Geigy Corp 2,2'-azines of 2,4-thiazolidinediones
AR204619A1 (es) * 1973-02-13 1976-02-20 Ciba Geigy Ag Procedimiento para la elaboracion de un nuevo derivado de 2,2-azina-2,4-tiazolidindiona
DE2632746A1 (de) * 1975-08-06 1977-02-24 Ciba Geigy Ag Methylen- oder substituierte methyl-thiazaheterocyclyl-azine
DE3002733A1 (de) * 1979-01-29 1980-08-07 Ciba Geigy Ag 4-alkylthiazolylphosphorsaeurederivate mit pestizider wirkung

Also Published As

Publication number Publication date
RO85276A (ro) 1984-09-29
PH20238A (en) 1986-10-10
CS241514B2 (en) 1986-03-13
AU555533B2 (en) 1986-10-02
RO87991B (ro) 1985-10-31
PL244185A1 (en) 1984-05-21
NZ202179A (en) 1986-04-11
NO823445L (no) 1983-07-25
EP0085275A1 (de) 1983-08-10
GR77024B (es) 1984-09-04
ES8603439A1 (es) 1985-12-16
HU188214B (en) 1986-03-28
GB2122604B (en) 1986-01-08
RO87991A (ro) 1985-11-30
DE3269209D1 (en) 1986-03-27
SU1318168A3 (ru) 1987-06-15
JPS58135871A (ja) 1983-08-12
FI823458A0 (fi) 1982-10-11
IL67023A0 (en) 1983-02-23
ATE18044T1 (de) 1986-03-15
SU1384202A3 (ru) 1988-03-23
DK451282A (da) 1983-07-23
CS742082A2 (en) 1985-08-15
PL238799A1 (en) 1984-02-27
SU1181545A3 (ru) 1985-09-23
ES535201A0 (es) 1985-12-16
ZA827444B (en) 1983-08-31
KR840001998A (ko) 1984-06-11
EP0085275B1 (de) 1986-02-19
RO85276B (ro) 1984-10-30
IL67023A (en) 1986-07-31
ES529335A0 (es) 1986-03-16
ES8605512A1 (es) 1986-03-16
US4489069A (en) 1984-12-18
PT75704B (en) 1985-12-03
KR880001716B1 (ko) 1988-09-08
AU8938982A (en) 1983-07-28
PL137949B1 (en) 1986-08-30
ES516888A0 (es) 1985-07-16
GB2122604A (en) 1984-01-18
DD203909A5 (de) 1983-11-09
PL138373B1 (en) 1986-09-30
PT75704A (en) 1982-11-01

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