ES8205231A1 - Procedimiento para preparar complejos de platino (iv)-diami-na - Google Patents

Procedimiento para preparar complejos de platino (iv)-diami-na

Info

Publication number
ES8205231A1
ES8205231A1 ES498240A ES498240A ES8205231A1 ES 8205231 A1 ES8205231 A1 ES 8205231A1 ES 498240 A ES498240 A ES 498240A ES 498240 A ES498240 A ES 498240A ES 8205231 A1 ES8205231 A1 ES 8205231A1
Authority
ES
Spain
Prior art keywords
platinum
preparation
diamine
mice
medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES498240A
Other languages
English (en)
Spanish (es)
Other versions
ES498240A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Original Assignee
Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO
Publication of ES498240A0 publication Critical patent/ES498240A0/es
Publication of ES8205231A1 publication Critical patent/ES8205231A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES498240A 1980-01-03 1980-12-30 Procedimiento para preparar complejos de platino (iv)-diami-na Expired ES8205231A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NLAANVRAGE8000032,A NL181434C (nl) 1980-01-03 1980-01-03 Platina(iv)-diamine-complexen, alsmede hun bereiding en toepassing.

Publications (2)

Publication Number Publication Date
ES498240A0 ES498240A0 (es) 1982-06-01
ES8205231A1 true ES8205231A1 (es) 1982-06-01

Family

ID=19834620

Family Applications (2)

Application Number Title Priority Date Filing Date
ES498240A Expired ES8205231A1 (es) 1980-01-03 1980-12-30 Procedimiento para preparar complejos de platino (iv)-diami-na
ES507474A Granted ES507474A0 (es) 1980-01-03 1981-11-26 Procedimiento para preparar complejos de platino (iv)-diami-na.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES507474A Granted ES507474A0 (es) 1980-01-03 1981-11-26 Procedimiento para preparar complejos de platino (iv)-diami-na.

Country Status (31)

Country Link
US (2) US4431666A (en, 2012)
JP (1) JPS56100796A (en, 2012)
AR (1) AR227903A1 (en, 2012)
AT (1) AT377242B (en, 2012)
AU (1) AU542600B2 (en, 2012)
BE (1) BE886929A (en, 2012)
CA (1) CA1154030A (en, 2012)
CH (1) CH650003A5 (en, 2012)
CS (1) CS239911B2 (en, 2012)
DD (1) DD156909A5 (en, 2012)
DE (1) DE3100017A1 (en, 2012)
DK (1) DK153468C (en, 2012)
ES (2) ES8205231A1 (en, 2012)
FI (1) FI72321C (en, 2012)
FR (1) FR2473046A1 (en, 2012)
GB (1) GB2066819B (en, 2012)
GR (1) GR72849B (en, 2012)
HU (1) HU184922B (en, 2012)
IE (1) IE50653B1 (en, 2012)
IL (1) IL61708A (en, 2012)
IT (1) IT1193395B (en, 2012)
LU (1) LU83046A1 (en, 2012)
NL (1) NL181434C (en, 2012)
NO (1) NO810004L (en, 2012)
NZ (1) NZ195926A (en, 2012)
PH (1) PH21998A (en, 2012)
PT (1) PT72298B (en, 2012)
SE (1) SE439921B (en, 2012)
SU (1) SU1083911A3 (en, 2012)
YU (1) YU41754B (en, 2012)
ZA (1) ZA8114B (en, 2012)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
US4786725A (en) * 1982-06-28 1988-11-22 Engelhard Corporation Solubilized platinum (II) complexes
US4598091A (en) * 1983-02-18 1986-07-01 Degussa Aktiengesellschaft (1,2-diphenyl)-ethylenediamine)-platinum (II) complex compounds
JPS6087295A (ja) * 1983-10-19 1985-05-16 Nippon Kayaku Co Ltd 新規白金錯体
IL74449A (en) * 1984-03-01 1988-07-31 Us Commerce Tetrahalo-1,2-cyclohexane-diamino platinum complexes and anti-neoplastic compositions comprising them
US4550187A (en) * 1984-04-12 1985-10-29 The Research Foundation Of State University Of New York Synthesis of platinum (IV) antineoplastic agents
HU193809B (en) * 1984-09-12 1987-12-28 Chugai Pharmaceutical Co Ltd Process for producing new platinum complexes
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
US4658047A (en) * 1985-09-27 1987-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method of preparing 1,2-diaminocyclohexane tetrachloro platinum (IV) isomers
US5117022A (en) * 1985-10-18 1992-05-26 The Board Of Regents, The University Of Texas System Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5041581A (en) * 1985-10-18 1991-08-20 The University Of Texas System Board Of Regents Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US5384127A (en) * 1985-10-18 1995-01-24 Board Of Regents, The University Of Texas System Stable liposomal formulations of lipophilic platinum compounds
US4760157A (en) * 1986-01-31 1988-07-26 American Cyanamid Company (2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
ATE86967T1 (de) * 1988-01-09 1993-04-15 Asta Medica Ag 1,2-bis(aminomethyl)cyclobutan-platin-komplexe.
NL8802149A (nl) * 1988-08-31 1990-03-16 Tno Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802150A (nl) * 1988-08-31 1990-03-16 Tno Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
US5196555A (en) * 1989-10-17 1993-03-23 Bristol-Myers Squibb Company Water and solvent soluble axial hydroxy and mono- and di- carboxylic acid derivatives having high tumor activity
FI905018A7 (fi) * 1989-10-17 1991-04-18 Bristol Myers Squibb Co Veteen ja liuottimeen liukenevat aksiaaliset hydroksi- ja mono- ja di-karboksyylihappojohdannaiset, joilla on korkea kasvainaktiivisuus
US5130450A (en) * 1990-04-25 1992-07-14 Nippon Kayaku Kabushiki Kaisha Platinum complexes
GB9211291D0 (en) * 1992-05-28 1992-07-15 British Tech Group Antifungal compounds
DE4415263C1 (de) * 1994-04-15 1995-11-30 Asta Medica Ag Cis-[trans-1,2-Cyclobutanbis(methylamin)-N,N']-[(2S)-lactato-O·1·, O·2·]-platin(II)-trihydrat (Lobaplatin-Trihydrat), seine Herstellung und arzneiliche Verwendung
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6264891B1 (en) * 1998-12-22 2001-07-24 Eos Biotechnology, Inc. Apparatus and method for concurrent chemical synthesis
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CN105198933B (zh) * 2014-06-20 2018-08-14 贵州益佰制药股份有限公司 一种洛铂晶体、制备方法及药物应用
KR20180019536A (ko) 2015-06-24 2018-02-26 니폰 가야꾸 가부시끼가이샤 신규한 백금(ⅳ) 착물
US10596191B2 (en) 2015-09-14 2020-03-24 Nippon Kayaku Kabushiki Kaisha Polymer conjugate of hexa-coordinated platinum complex
CN105713046B (zh) * 2016-02-01 2018-10-26 复旦大学 一种铂类抗肿瘤前体药物，其纳米水凝胶药物及其制备方法
CN106946946A (zh) * 2017-03-29 2017-07-14 昆明贵研药业有限公司 一种铂类抗肿瘤药物米铂氧化物的制备方法
US20220306670A1 (en) * 2019-06-18 2022-09-29 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Site-specific, kinetically inert conjugation of labels and/or carriers to target molecules such as his-tagged proteins via metal complex reagents

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH605550A5 (en, 2012) * 1972-06-08 1978-09-29 Research Corp
US4053587A (en) * 1973-04-13 1977-10-11 Research Corporation Method of treating viral infections
GB1578323A (en) * 1976-02-26 1980-11-05 Rustenburg Platinum Mines Ltd Compositions containing platinum
SE7810798L (sv) * 1977-10-19 1979-04-20 Johnson Matthey Co Ltd Kompositioner, innehallande platina
GB2019405A (en) * 1978-04-20 1979-10-31 Johnson Matthey & Co Ltd Pt Pt (II) and (IV) Amino-Acid Complexes
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
SE7903359L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体

Also Published As

Publication number Publication date
NZ195926A (en) 1983-04-12
US4431666A (en) 1984-02-14
FI72321B (fi) 1987-01-30
IT8027029A0 (it) 1980-12-31
NO810004L (no) 1981-07-06
YU336380A (en) 1983-10-31
GB2066819A (en) 1981-07-15
FI72321C (fi) 1987-05-11
ES8207119A1 (es) 1982-09-01
CH650003A5 (de) 1985-06-28
DK153468B (da) 1988-07-18
AR227903A1 (es) 1982-12-30
AT377242B (de) 1985-02-25
FR2473046A1 (fr) 1981-07-10
JPS56100796A (en) 1981-08-12
NL181434C (nl) 1987-08-17
IE802744L (en) 1981-07-03
GB2066819B (en) 1984-01-18
ES507474A0 (es) 1982-09-01
FI810002L (fi) 1981-07-04
DK153468C (da) 1988-12-12
AU6594981A (en) 1981-07-09
NL181434B (nl) 1987-03-16
LU83046A1 (de) 1981-03-27
SE439921B (sv) 1985-07-08
ZA8114B (en) 1982-01-27
CA1154030A (en) 1983-09-20
IL61708A (en) 1984-05-31
SE8100006L (sv) 1981-07-04
DK1681A (da) 1981-07-04
FR2473046B1 (en, 2012) 1985-03-01
PT72298A (en) 1981-01-01
IE50653B1 (en) 1986-06-11
ES498240A0 (es) 1982-06-01
IT1193395B (it) 1988-06-15
DD156909A5 (de) 1982-09-29
BE886929A (nl) 1981-06-30
HU184922B (en) 1984-11-28
IL61708A0 (en) 1981-01-30
PH21998A (en) 1988-05-02
ATA381A (de) 1984-07-15
YU41754B (en) 1987-12-31
DE3100017A1 (de) 1981-11-19
NL8000032A (nl) 1981-08-03
AU542600B2 (en) 1985-02-28
SU1083911A3 (ru) 1984-03-30
GR72849B (en, 2012) 1983-12-07
JPH0428716B2 (en, 2012) 1992-05-15
CS239911B2 (en) 1986-01-16
US4482569A (en) 1984-11-13
PT72298B (en) 1981-11-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401