ES8203388A1 - Un procedimiento para la preparacion de nuevos derivados de imidazo-rifamicina - Google Patents

Un procedimiento para la preparacion de nuevos derivados de imidazo-rifamicina

Info

Publication number
ES8203388A1
ES8203388A1 ES502906A ES502906A ES8203388A1 ES 8203388 A1 ES8203388 A1 ES 8203388A1 ES 502906 A ES502906 A ES 502906A ES 502906 A ES502906 A ES 502906A ES 8203388 A1 ES8203388 A1 ES 8203388A1
Authority
ES
Spain
Prior art keywords
nil
alkyl
hydrogen
imidazo
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502906A
Other languages
English (en)
Spanish (es)
Other versions
ES502906A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Farmaceutici SpA
Original Assignee
Alfa Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Farmaceutici SpA filed Critical Alfa Farmaceutici SpA
Publication of ES502906A0 publication Critical patent/ES502906A0/es
Publication of ES8203388A1 publication Critical patent/ES8203388A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES502906A 1980-05-22 1981-05-21 Un procedimiento para la preparacion de nuevos derivados de imidazo-rifamicina Expired ES8203388A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT03429/80A IT1154655B (it) 1980-05-22 1980-05-22 Derivati imidazo-rifamicinici metodi per la loro preparazione e loro uso come sostanza ad azione antibatterica

Publications (2)

Publication Number Publication Date
ES502906A0 ES502906A0 (es) 1982-04-01
ES8203388A1 true ES8203388A1 (es) 1982-04-01

Family

ID=11107198

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502906A Expired ES8203388A1 (es) 1980-05-22 1981-05-21 Un procedimiento para la preparacion de nuevos derivados de imidazo-rifamicina

Country Status (25)

Country Link
US (1) US4341785A (cg-RX-API-DMAC7.html)
JP (1) JPS5711987A (cg-RX-API-DMAC7.html)
AR (1) AR226212A1 (cg-RX-API-DMAC7.html)
AT (1) AT373599B (cg-RX-API-DMAC7.html)
AU (1) AU537093B2 (cg-RX-API-DMAC7.html)
BE (1) BE888895A (cg-RX-API-DMAC7.html)
CA (1) CA1142518A (cg-RX-API-DMAC7.html)
CH (1) CH648037A5 (cg-RX-API-DMAC7.html)
DE (1) DE3120460A1 (cg-RX-API-DMAC7.html)
DK (1) DK157876C (cg-RX-API-DMAC7.html)
EG (1) EG14891A (cg-RX-API-DMAC7.html)
ES (1) ES8203388A1 (cg-RX-API-DMAC7.html)
FI (1) FI69467C (cg-RX-API-DMAC7.html)
FR (1) FR2482967A1 (cg-RX-API-DMAC7.html)
GB (1) GB2079270B (cg-RX-API-DMAC7.html)
GR (1) GR75640B (cg-RX-API-DMAC7.html)
IE (1) IE51204B1 (cg-RX-API-DMAC7.html)
IT (1) IT1154655B (cg-RX-API-DMAC7.html)
LU (1) LU83376A1 (cg-RX-API-DMAC7.html)
NL (1) NL187022C (cg-RX-API-DMAC7.html)
NO (1) NO155622C (cg-RX-API-DMAC7.html)
PH (2) PH17207A (cg-RX-API-DMAC7.html)
PT (1) PT73064B (cg-RX-API-DMAC7.html)
SE (1) SE453089B (cg-RX-API-DMAC7.html)
ZA (1) ZA813430B (cg-RX-API-DMAC7.html)

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US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
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WO2003051299A2 (en) * 2001-12-13 2003-06-26 Activbiotics, Inc. Sulfhydryl rifamycins and uses thereof
US8758804B2 (en) * 2002-11-05 2014-06-24 Fadim S.R.L. Controlled and continued delivery of rifaximin and/or other substances
US7820652B2 (en) * 2003-09-24 2010-10-26 Activbiotics Pharma, Llc Regimen for the administration of rifamycin-class antibiotics
ITMI20032144A1 (it) * 2003-11-07 2005-05-08 Alfa Wassermann Spa Forme polimorfe di rifaximina, processi per ottenerle e
US7902206B2 (en) * 2003-11-07 2011-03-08 Alfa Wassermann, S.P.A. Polymorphic forms α, β and γ of rifaximin
US7923553B2 (en) * 2003-11-07 2011-04-12 Alfa Wassermann, S.P.A. Processes for the production of polymorphic forms of rifaximin
US7906542B2 (en) * 2004-11-04 2011-03-15 Alfa Wassermann, S.P.A. Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin
US20080262024A1 (en) * 2003-11-07 2008-10-23 Giuseppe Claudio Viscomi Rifaximin compositions and method of use
US7265107B2 (en) * 2004-03-10 2007-09-04 Cumbre Pharmaceuticals Inc. Rifamycin C-11 oxime cyclo derivatives effective against drug-resistant microbes
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US7202246B2 (en) * 2004-06-09 2007-04-10 Cumbre Pharmaceuticals Inc. Spiro-rifamycin derivatives targeting RNA polymerase
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US8003118B2 (en) * 2005-03-02 2011-08-23 Kodsi Robert E Use of rifaximin for the prevention of aspiration pneumonia and/or sepsis
US20060210483A1 (en) * 2005-03-02 2006-09-21 Kodsi Robert E Non-systemic antibiotic formulations and related method of use and treatment of upper respiratory infections
PL1698630T3 (pl) 2005-03-03 2014-12-31 Alfasigma Spa Nowe postacie polimorficzne rifaksyminy,sposoby ich wytwarzania i ich zastosowanie w preparatach leczniczych
ITBO20050123A1 (it) 2005-03-07 2005-06-06 Alfa Wassermann Spa Formulazioni farmaceutiche gastroresistenti contenenti rifaximina
KR101327635B1 (ko) 2005-08-11 2013-11-12 타간타 테라퓨틱스 인크. 포스폰산화 리파마이신, 및 그의 뼈 및 관절 감염의 저지및 치료 용도
WO2007103448A2 (en) 2006-03-09 2007-09-13 Salix Pharmaceuticals, Inc. Rifaximin anti-rectal dysfunction preparation
EP2054066B1 (en) 2006-08-02 2015-04-15 Salix Pharmaceuticals, Inc. Methods for treatment of radiation enteritis
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US8633234B2 (en) * 2006-09-22 2014-01-21 Cipla Limited Rifaximin
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US20080159987A1 (en) * 2007-01-03 2008-07-03 Leonard Weinstock Use of Rifaximin for the Treatment of Restless Legs Syndrome
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US8383151B2 (en) 2007-07-06 2013-02-26 Lupin Limited Pharmaceutical compositions of rifaximin
DK2011486T3 (da) 2007-07-06 2012-09-03 Lupin Ltd Farmaceutiske sammensætninger af rifaximin
US7709634B2 (en) * 2007-09-20 2010-05-04 Apotex Pharmachem Inc. Amorphous form of rifaximin and processes for its preparation
KR101674382B1 (ko) * 2008-02-25 2016-11-09 샐릭스 파마슈티컬스 리미티드 리팍시민의 형태 및 이의 용도
US8486956B2 (en) 2008-02-25 2013-07-16 Salix Pharmaceuticals, Ltd Forms of rifaximin and uses thereof
MX2010009197A (es) 2008-02-26 2010-11-22 Salix Pharmaceuticals Ltd Metodos para tratar padecimientos del intestino.
US11779571B2 (en) 2008-02-26 2023-10-10 Salix Pharmaceuticals, Inc. Methods for treating irritable bowel syndrome (IBS)
PT2294012E (pt) 2008-05-07 2014-10-15 Salix Pharmaceuticals Ltd Administração de um agente de limpeza intestinal e de um antibiótico para o tratamento de doença intestinal
US8524691B2 (en) 2008-08-13 2013-09-03 The Medicines Company Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
PL2327407T3 (pl) 2008-09-26 2014-12-31 Alfasigma Spa Środek profilaktyczny i/lub terapeutyczny na zaburzenia czynnościowe przewodu pokarmowego
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US12285414B2 (en) 2008-10-02 2025-04-29 Salix Pharmaceuticals, Inc. Methods of treating hepatic encephalopathy
ES2718614T3 (es) 2008-12-10 2019-07-03 Cipla Ltd Complejos de rifaximina
IT1397617B1 (it) * 2009-04-20 2013-01-18 Alfa Wassermann Spa Nuovi derivati della rifamicina
KR20190099100A (ko) 2009-06-02 2019-08-23 샐릭스 파마슈티컬스 리미티드 간성 뇌병증의 치료방법
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RU2012121599A (ru) 2009-10-27 2013-12-10 Люпин Лимитед Твердая дисперсия рифаксимина
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US8952159B2 (en) 2009-12-28 2015-02-10 Silvio Massimo Lavagna Method for the production of amorphous rifaximin
EP2536282A4 (en) 2010-02-18 2013-07-03 Salix Pharmaceuticals Ltd METHOD FOR THE TREATMENT OF INFECTIONS
IT1398550B1 (it) 2010-03-05 2013-03-01 Alfa Wassermann Spa Formulazioni comprendenti rifaximina utili per ottenere un effetto prolungato nel tempo
AU2011225810B2 (en) 2010-03-10 2014-11-06 Lupin Limited Rifaximin ready-to-use suspension
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WO2012035544A2 (en) 2010-09-13 2012-03-22 Sequent Scientific Ltd. A novel polymorphic form of rifaximin and process for its preparation
PL2672970T3 (pl) 2011-02-11 2018-11-30 Salix Pharmaceuticals, Ltd. Postacie rifaksyminy i sposoby ich wykorzystania
AU2012251385A1 (en) 2011-05-02 2013-11-21 Ranbaxy Laboratories Limited Rifaximin dimethylformamide solvate
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ITBO20110461A1 (it) 2011-07-29 2013-01-30 Alfa Wassermann Spa Composizioni farmaceutiche comprendenti rifaximina, processi per la loro preparazione e loro uso nel trattamento di infezioni vaginali.
RU2496475C2 (ru) 2011-10-26 2013-10-27 Александр Васильевич Иващенко Фармацевтическая композиция и набор для лечения бактериальных инфекций
US20130184302A1 (en) 2011-11-02 2013-07-18 Enoch Bortey Methods for treating irritable bowel syndrome (ibs) and infections
WO2013112809A2 (en) 2012-01-25 2013-08-01 Salix Pharmaceuticals, Ltd Rifaximin derivative and uses thereof
ITBO20120368A1 (it) 2012-07-06 2014-01-07 Alfa Wassermann Spa Composizioni comprendenti rifaximina e amminoacidi, cristalli di rifaximina derivanti da tali composizioni e loro uso.
WO2014091432A1 (en) 2012-12-12 2014-06-19 Ranbaxy Laboratories Limited Pharmaceutical compositions of rifaximin
CA2897758A1 (en) 2013-03-15 2014-09-18 Alfa Wassermann S.P.A. Rifaximin for use in the treating of vaginal infections
US20160047819A1 (en) 2013-03-15 2016-02-18 Alfa Wassermann S.P.A. Method for diagnosing vaginal infections
WO2014167533A1 (en) 2013-04-12 2014-10-16 Alfa Wassermann S.P.A. Nsaid administration and related compositions, methods and systems.
US9018225B1 (en) 2013-07-26 2015-04-28 Novel Laboratories Rifaximin crystalline forms and methods of preparation thereof
EP2927235B1 (en) 2014-03-31 2017-02-08 Euticals S.P.A. Polymorphic mixture of rifaximin and its use for the preparation of solid formulations
CA2946101A1 (en) * 2014-04-19 2015-10-22 Granules India Limited An improved process for the preparation of rifamycin derivatives
WO2015171493A1 (en) 2014-05-04 2015-11-12 Salix Pharmaceuticals, Inc. Ibs microbiota and uses thereof
PT3143027T (pt) 2014-05-12 2019-09-20 Alfasigma Spa Nova forma de cristal solvatado de rifaximina, produção, composições e utilização dos mesmos
EP2982764A1 (en) 2014-08-05 2016-02-10 ALFA WASSERMANN S.p.A. Identification of vaginal bacteria
US9988398B2 (en) 2016-06-07 2018-06-05 Cadila Healthcare Limited Crystalline form of rifaximin and process for its preparation
RS63751B1 (sr) 2016-09-30 2022-12-30 Salix Pharmaceuticals Inc Čvrsti disperzioni oblici rifaksimina
IT201700091912A1 (it) * 2017-08-08 2019-02-08 Biofer Spa Nuove pirido-imidazo rifamicine
RU2020102511A (ru) * 2017-06-26 2021-07-27 Биофер С.П.А. Соединения пиридо-имидазо рифамицина в качестве антибактериального средства

Family Cites Families (6)

* Cited by examiner, † Cited by third party
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DE273377C (cg-RX-API-DMAC7.html) *
AT273377B (de) * 1967-03-01 1969-08-11 Lepetit Spa Verfahren zur Herstellung von neuen Rifamycinen
AT344898B (de) * 1975-06-13 1978-08-10 Archifar Ind Chim Trentino Verfahren zur herstellung neuer rifamycin-verbindungen
DK345977A (da) * 1976-09-30 1978-03-31 Archifar Ind Chim Trentino G rifamycinforbindelser og fremgangsmaade til deres fremstillin
CH629212A5 (it) * 1976-10-18 1982-04-15 Erba Farmitalia Procedimento per la preparazione di composti di rifamicina.
CH633014A5 (en) * 1978-06-09 1982-11-15 Erba Farmitalia Rifamycin compounds

Also Published As

Publication number Publication date
FI811565L (fi) 1981-11-23
NL8102290A (nl) 1981-12-16
PH17207A (en) 1984-06-19
SE453089B (sv) 1988-01-11
JPS5711987A (en) 1982-01-21
CA1142518A (en) 1983-03-08
IE811139L (en) 1981-11-22
BE888895A (fr) 1981-09-16
DK224781A (da) 1981-11-23
LU83376A1 (fr) 1981-09-11
NO811731L (no) 1981-11-23
NL187022B (nl) 1990-12-03
DK157876B (da) 1990-02-26
PT73064B (en) 1982-07-05
SE8103216L (sv) 1981-11-23
PT73064A (en) 1981-06-01
GB2079270B (en) 1984-01-18
AU7065581A (en) 1981-11-26
NO155622B (no) 1987-01-19
IE51204B1 (en) 1986-10-29
FI69467C (fi) 1986-02-10
AR226212A1 (es) 1982-06-15
IT8003429A0 (it) 1980-05-22
ATA222781A (de) 1983-06-15
FI69467B (fi) 1985-10-31
GB2079270A (en) 1982-01-20
ZA813430B (en) 1982-06-30
ES502906A0 (es) 1982-04-01
CH648037A5 (de) 1985-02-28
PH18704A (en) 1985-09-05
US4341785A (en) 1982-07-27
GR75640B (cg-RX-API-DMAC7.html) 1984-08-02
EG14891A (en) 1985-12-31
IT1154655B (it) 1987-01-21
FR2482967A1 (fr) 1981-11-27
AU537093B2 (en) 1984-06-07
DE3120460C2 (cg-RX-API-DMAC7.html) 1990-12-13
NL187022C (nl) 1991-05-01
DK157876C (da) 1990-07-30
NO155622C (no) 1987-04-29
FR2482967B1 (cg-RX-API-DMAC7.html) 1985-03-29
JPS6123192B2 (cg-RX-API-DMAC7.html) 1986-06-04
DE3120460A1 (de) 1982-03-11
AT373599B (de) 1984-02-10

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FD1A Patent lapsed

Effective date: 20020205