ES8203349A1 - Un procedimiento para la preparacion de 1,2-bis(nicotinami- do) propano - Google Patents

Un procedimiento para la preparacion de 1,2-bis(nicotinami- do) propano

Info

Publication number
ES8203349A1
ES8203349A1 ES497065A ES497065A ES8203349A1 ES 8203349 A1 ES8203349 A1 ES 8203349A1 ES 497065 A ES497065 A ES 497065A ES 497065 A ES497065 A ES 497065A ES 8203349 A1 ES8203349 A1 ES 8203349A1
Authority
ES
Spain
Prior art keywords
propane
bis
procedure
preparation
nicotinic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497065A
Other languages
English (en)
Spanish (es)
Other versions
ES497065A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of ES497065A0 publication Critical patent/ES497065A0/es
Publication of ES8203349A1 publication Critical patent/ES8203349A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
ES497065A 1979-11-22 1980-11-21 Un procedimiento para la preparacion de 1,2-bis(nicotinami- do) propano Expired ES8203349A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15067479A JPS5675474A (en) 1979-11-22 1979-11-22 Nicotinamide derivative and medicine containing the same

Publications (2)

Publication Number Publication Date
ES497065A0 ES497065A0 (es) 1982-04-01
ES8203349A1 true ES8203349A1 (es) 1982-04-01

Family

ID=15501986

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497065A Expired ES8203349A1 (es) 1979-11-22 1980-11-21 Un procedimiento para la preparacion de 1,2-bis(nicotinami- do) propano

Country Status (13)

Country Link
US (1) US4366161A (enExample)
EP (1) EP0029602B1 (enExample)
JP (1) JPS5675474A (enExample)
AR (1) AR229954A1 (enExample)
AU (1) AU540216B2 (enExample)
CA (1) CA1147732A (enExample)
CS (1) CS241475B2 (enExample)
DE (1) DE3066874D1 (enExample)
DK (1) DK149807C (enExample)
ES (1) ES8203349A1 (enExample)
HU (1) HU180617B (enExample)
SU (1) SU1053749A3 (enExample)
ZA (1) ZA807283B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1170214B (it) * 1983-09-12 1987-06-03 Crinos Industria Farmaco Composizione farmaceutica per la cura delle arteriopatie periferiche
FR2556722B1 (fr) * 1983-12-15 1986-09-26 Merck Clevenot Laboratoires N-valproyl-nicotinamide, procede de preparation et utilisation en therapeutique
ES2061918T3 (es) * 1988-12-27 1994-12-16 Chugai Pharmaceutical Co Ltd Procedimiento para la purificacion de 1,2-bis (nicotinamido) propano.
EP0697169B1 (en) * 1993-05-07 2000-11-15 Chugai Seiyaku Kabushiki Kaisha Organ preservative
JPH09315972A (ja) * 1996-03-22 1997-12-09 Chugai Pharmaceut Co Ltd 脊髄損傷治療剤
JP3860752B2 (ja) * 2000-03-17 2006-12-20 利男 田中 ヘムオキシゲナーゼ−１の誘導または誘導増強剤
WO2002028392A1 (en) * 2000-09-29 2002-04-11 Chugai Seiyaku Kabushiki Kaisha Remedies for brain circulatory disturbances

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH392507A (de) * 1960-06-27 1965-05-31 Eprova Ag Verfahren zur Herstellung von Nicotinsäure-aminomethylamiden
FR1335517A (fr) * 1962-03-27 1963-08-23 Ciba Geigy Procédé de préparation d'amides hétérocycliques, notamment de la 3, 3-bis-(4-nicotinoylamino-phényl)-butane-2-one
US3697531A (en) * 1971-02-25 1972-10-10 Sterling Drug Inc N,n{40 -alkylenebis(pyridine-carboxamides)
GB1339764A (en) * 1971-03-29 1973-12-05 Ici Ltd Pyridine derivatives

Also Published As

Publication number Publication date
ES497065A0 (es) 1982-04-01
HU180617B (en) 1983-03-28
CS765780A2 (en) 1985-07-16
AR229954A1 (es) 1984-01-31
JPS5675474A (en) 1981-06-22
SU1053749A3 (ru) 1983-11-07
CS241475B2 (en) 1986-03-13
DK493780A (da) 1981-05-23
DK149807C (da) 1987-03-23
AU540216B2 (en) 1984-11-08
DE3066874D1 (en) 1984-04-12
AU6451780A (en) 1981-05-28
ZA807283B (en) 1981-11-25
US4366161A (en) 1982-12-28
JPS6155911B2 (enExample) 1986-11-29
CA1147732A (en) 1983-06-07
DK149807B (da) 1986-10-06
EP0029602A1 (en) 1981-06-03
EP0029602B1 (en) 1984-03-07

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