JPS5675474A - Nicotinamide derivative and medicine containing the same - Google Patents
Nicotinamide derivative and medicine containing the sameInfo
- Publication number
- JPS5675474A JPS5675474A JP15067479A JP15067479A JPS5675474A JP S5675474 A JPS5675474 A JP S5675474A JP 15067479 A JP15067479 A JP 15067479A JP 15067479 A JP15067479 A JP 15067479A JP S5675474 A JPS5675474 A JP S5675474A
- Authority
- JP
- Japan
- Prior art keywords
- same
- medicine containing
- low
- nicotinamide derivative
- level
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15067479A JPS5675474A (en) | 1979-11-22 | 1979-11-22 | Nicotinamide derivative and medicine containing the same |
CS807657A CS241475B2 (en) | 1979-11-22 | 1980-11-12 | Method of 1,2-bis/(nicotinamido/)-propane preparation |
US06/207,443 US4366161A (en) | 1979-11-22 | 1980-11-17 | Nicotinamide derivative, process for preparing the same and pharmaceutical composition containing the same |
DK493780A DK149807C (da) | 1979-11-22 | 1980-11-19 | Analogifremgangsmaade til fremstilling af 1,2-bis-(nicotinamido)-propan |
AR283298A AR229954A1 (es) | 1979-11-22 | 1980-11-19 | Procedimiento de preparacion de 1,2-bis(nicotinamido)propano o sus sales farmaceuticamente adecuadas |
AU64517/80A AU540216B2 (en) | 1979-11-22 | 1980-11-19 | Nicotinamide derivative, process for preparing the same and pharmaceutical composition containing the same |
SU803009644A SU1053749A3 (ru) | 1979-11-22 | 1980-11-21 | Способ получени 1,2-бис-(никотинамидо)-пропана или его солей с фармацевтически приемлемой кислотой |
HU80802785A HU180617B (en) | 1979-11-22 | 1980-11-21 | Process for producing 1,2-bis-bracket-nicotinamido-bracket closed-propane,salts and pharmaceutical compositions containing them |
EP80107287A EP0029602B1 (en) | 1979-11-22 | 1980-11-21 | 1,2-bis(nicotinamido)propane, process for preparing the same and pharmaceutical composition containing the same |
ES497065A ES497065A0 (es) | 1979-11-22 | 1980-11-21 | Un procedimiento para la preparacion de 1,2-bis(nicotinami- do) propano |
ZA00807283A ZA807283B (en) | 1979-11-22 | 1980-11-21 | Nicotinamide derivative,process for preparing the same and pharmaceutical composition containing the same |
DE8080107287T DE3066874D1 (en) | 1979-11-22 | 1980-11-21 | 1,2-bis(nicotinamido)propane, process for preparing the same and pharmaceutical composition containing the same |
CA000365220A CA1147732A (en) | 1979-11-22 | 1980-11-21 | 1,2-bis(nicotinamido)propane same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15067479A JPS5675474A (en) | 1979-11-22 | 1979-11-22 | Nicotinamide derivative and medicine containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5675474A true JPS5675474A (en) | 1981-06-22 |
JPS6155911B2 JPS6155911B2 (ja) | 1986-11-29 |
Family
ID=15501986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15067479A Granted JPS5675474A (en) | 1979-11-22 | 1979-11-22 | Nicotinamide derivative and medicine containing the same |
Country Status (13)
Country | Link |
---|---|
US (1) | US4366161A (ja) |
EP (1) | EP0029602B1 (ja) |
JP (1) | JPS5675474A (ja) |
AR (1) | AR229954A1 (ja) |
AU (1) | AU540216B2 (ja) |
CA (1) | CA1147732A (ja) |
CS (1) | CS241475B2 (ja) |
DE (1) | DE3066874D1 (ja) |
DK (1) | DK149807C (ja) |
ES (1) | ES497065A0 (ja) |
HU (1) | HU180617B (ja) |
SU (1) | SU1053749A3 (ja) |
ZA (1) | ZA807283B (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1170214B (it) * | 1983-09-12 | 1987-06-03 | Crinos Industria Farmaco | Composizione farmaceutica per la cura delle arteriopatie periferiche |
FR2556722B1 (fr) * | 1983-12-15 | 1986-09-26 | Merck Clevenot Laboratoires | N-valproyl-nicotinamide, procede de preparation et utilisation en therapeutique |
ES2061918T3 (es) * | 1988-12-27 | 1994-12-16 | Chugai Pharmaceutical Co Ltd | Procedimiento para la purificacion de 1,2-bis (nicotinamido) propano. |
DE69426295T2 (de) * | 1993-05-07 | 2001-04-05 | Chugai Pharmaceutical Co Ltd | Organkonservierungsmittel |
JPH09315972A (ja) * | 1996-03-22 | 1997-12-09 | Chugai Pharmaceut Co Ltd | 脊髄損傷治療剤 |
EP1266660A4 (en) * | 2000-03-17 | 2006-03-22 | Toshio Tanaka | HEME OXYGENASE-1 INDUCTORS OR THEIR PREVENTIVE REINFORCING MEDIUM |
AU2001292272A1 (en) * | 2000-09-29 | 2002-04-15 | Chugai Seiyaku Kabushiki Kaisha | Remedies for brain circulatory disturbances |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH392507A (de) * | 1960-06-27 | 1965-05-31 | Eprova Ag | Verfahren zur Herstellung von Nicotinsäure-aminomethylamiden |
FR1335517A (fr) * | 1962-03-27 | 1963-08-23 | Ciba Geigy | Procédé de préparation d'amides hétérocycliques, notamment de la 3, 3-bis-(4-nicotinoylamino-phényl)-butane-2-one |
US3697531A (en) * | 1971-02-25 | 1972-10-10 | Sterling Drug Inc | N,n{40 -alkylenebis(pyridine-carboxamides) |
GB1339764A (en) * | 1971-03-29 | 1973-12-05 | Ici Ltd | Pyridine derivatives |
-
1979
- 1979-11-22 JP JP15067479A patent/JPS5675474A/ja active Granted
-
1980
- 1980-11-12 CS CS807657A patent/CS241475B2/cs unknown
- 1980-11-17 US US06/207,443 patent/US4366161A/en not_active Expired - Lifetime
- 1980-11-19 AR AR283298A patent/AR229954A1/es active
- 1980-11-19 AU AU64517/80A patent/AU540216B2/en not_active Expired
- 1980-11-19 DK DK493780A patent/DK149807C/da not_active IP Right Cessation
- 1980-11-21 HU HU80802785A patent/HU180617B/hu unknown
- 1980-11-21 ZA ZA00807283A patent/ZA807283B/xx unknown
- 1980-11-21 CA CA000365220A patent/CA1147732A/en not_active Expired
- 1980-11-21 ES ES497065A patent/ES497065A0/es active Granted
- 1980-11-21 SU SU803009644A patent/SU1053749A3/ru active
- 1980-11-21 DE DE8080107287T patent/DE3066874D1/de not_active Expired
- 1980-11-21 EP EP80107287A patent/EP0029602B1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0029602B1 (en) | 1984-03-07 |
ES8203349A1 (es) | 1982-04-01 |
SU1053749A3 (ru) | 1983-11-07 |
DK493780A (da) | 1981-05-23 |
AU6451780A (en) | 1981-05-28 |
AU540216B2 (en) | 1984-11-08 |
DK149807C (da) | 1987-03-23 |
ZA807283B (en) | 1981-11-25 |
AR229954A1 (es) | 1984-01-31 |
US4366161A (en) | 1982-12-28 |
CS241475B2 (en) | 1986-03-13 |
CS765780A2 (en) | 1985-07-16 |
HU180617B (en) | 1983-03-28 |
JPS6155911B2 (ja) | 1986-11-29 |
CA1147732A (en) | 1983-06-07 |
DE3066874D1 (en) | 1984-04-12 |
DK149807B (da) | 1986-10-06 |
EP0029602A1 (en) | 1981-06-03 |
ES497065A0 (es) | 1982-04-01 |
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