ES475471A1 - Procedimiento para la preparacion de 3-yodo- y 3-bromorrifa-micina s. - Google Patents
Procedimiento para la preparacion de 3-yodo- y 3-bromorrifa-micina s.Info
- Publication number
- ES475471A1 ES475471A1 ES475471A ES475471A ES475471A1 ES 475471 A1 ES475471 A1 ES 475471A1 ES 475471 A ES475471 A ES 475471A ES 475471 A ES475471 A ES 475471A ES 475471 A1 ES475471 A1 ES 475471A1
- Authority
- ES
- Spain
- Prior art keywords
- bromorifamycin
- iodo
- preparation
- halogen
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Procedimiento para la preparación de 3 yodo y 3-bromorrifamicina S, caracterizado porque se hace reaccionar rifamicina S con, por lo menos, dos equivalentes de un halógeno elegido del grupo constituido por yodo y bromo, por mol de rifamicina S en presencia de, por lo menos, un mol de piridina por cada equivalente de halógeno y en presencia de un disolvente polar e hidrofílico inerte, operando a una temperatura no superior a la temperatura del ambiente.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT03620/77A IT1090759B (it) | 1977-11-29 | 1977-11-29 | Procedimento per la preparazione di 3 iodio e 3 bromo rifamicina s |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES475471A1 true ES475471A1 (es) | 1979-06-01 |
Family
ID=11110742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES475471A Expired ES475471A1 (es) | 1977-11-29 | 1978-11-28 | Procedimiento para la preparacion de 3-yodo- y 3-bromorrifa-micina s. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US4179438A (es) |
| JP (1) | JPS5495599A (es) |
| AR (1) | AR219775A1 (es) |
| AT (1) | AT360652B (es) |
| AU (1) | AU519242B2 (es) |
| BE (1) | BE872294A (es) |
| CA (1) | CA1099265A (es) |
| CH (1) | CH636619A5 (es) |
| DE (1) | DE2851312A1 (es) |
| DK (1) | DK155797C (es) |
| ES (1) | ES475471A1 (es) |
| FI (1) | FI65254C (es) |
| FR (1) | FR2410000A1 (es) |
| GB (1) | GB2009744B (es) |
| GR (1) | GR71727B (es) |
| IT (1) | IT1090759B (es) |
| LU (1) | LU80567A1 (es) |
| NL (1) | NL7811558A (es) |
| NO (1) | NO784005L (es) |
| PT (1) | PT68840A (es) |
| SE (1) | SE439168B (es) |
| YU (1) | YU279178A (es) |
| ZA (1) | ZA786299B (es) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL100642A (en) * | 1991-01-28 | 1995-11-27 | Lepetit Spa | Process for the preparation of (2-) diethylamino (rifmacin P) AED / P (and its new intermediate |
| US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
| US6861053B1 (en) | 1999-08-11 | 2005-03-01 | Cedars-Sinai Medical Center | Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth |
| US7247634B2 (en) * | 2004-01-13 | 2007-07-24 | Cumbre Pharmaceuticals Inc. | Rifamycin derivatives effective against drug-resistant microbes |
| US9415112B2 (en) | 2011-06-20 | 2016-08-16 | Rutgers, The State University Of New Jersey | Bipartite inhibitors of bacterial RNA polymerase |
| US9108968B2 (en) | 2012-04-25 | 2015-08-18 | Ppg Industries Ohio, Inc. | Methods for producing 1,5,7-triazabicyclo[4.4.0]dec-5-ene by reaction of a disubstituted carbodiimide and dipropylene triamine |
| EP3134415A4 (en) * | 2014-04-19 | 2017-10-25 | Granules India Limited | An improved process for the preparation of rifamycin derivatives |
| DK3645539T3 (da) | 2017-06-26 | 2021-05-10 | Biofer Spa | Pyrido-imidazo-rifamycin-derivater som antibakterielt middel |
| CN109400628A (zh) * | 2018-12-26 | 2019-03-01 | 重庆华邦胜凯制药有限公司 | 一种利福布汀中间体的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1053787B (it) * | 1974-10-29 | 1981-10-10 | Pastori A | Macrolidi azotati e loro preparazione |
| GB1591696A (en) * | 1978-03-09 | 1981-06-24 | Archifar Lab Chim Farm | 3-nitro-rifamycins s and sv |
-
1977
- 1977-11-29 IT IT03620/77A patent/IT1090759B/it active
-
1978
- 1978-11-06 US US05/957,844 patent/US4179438A/en not_active Expired - Lifetime
- 1978-11-08 ZA ZA00786299A patent/ZA786299B/xx unknown
- 1978-11-23 AT AT837078A patent/AT360652B/de not_active IP Right Cessation
- 1978-11-23 AU AU41867/78A patent/AU519242B2/en not_active Expired
- 1978-11-23 LU LU80567A patent/LU80567A1/xx unknown
- 1978-11-24 NL NL7811558A patent/NL7811558A/xx not_active Application Discontinuation
- 1978-11-27 FR FR7833394A patent/FR2410000A1/fr active Granted
- 1978-11-27 AR AR274585A patent/AR219775A1/es active
- 1978-11-27 DE DE19782851312 patent/DE2851312A1/de not_active Withdrawn
- 1978-11-27 BE BE2057442A patent/BE872294A/xx not_active IP Right Cessation
- 1978-11-27 YU YU02791/78A patent/YU279178A/xx unknown
- 1978-11-28 ES ES475471A patent/ES475471A1/es not_active Expired
- 1978-11-28 NO NO784005A patent/NO784005L/no unknown
- 1978-11-28 DK DK530978A patent/DK155797C/da not_active IP Right Cessation
- 1978-11-28 SE SE7812231A patent/SE439168B/sv not_active IP Right Cessation
- 1978-11-28 CA CA317,009A patent/CA1099265A/en not_active Expired
- 1978-11-28 GR GR57753A patent/GR71727B/el unknown
- 1978-11-28 CH CH1217978A patent/CH636619A5/it not_active IP Right Cessation
- 1978-11-28 FI FI783639A patent/FI65254C/fi not_active IP Right Cessation
- 1978-11-28 JP JP14704878A patent/JPS5495599A/ja active Granted
- 1978-11-28 PT PT68840A patent/PT68840A/pt unknown
- 1978-11-29 GB GB7846449A patent/GB2009744B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FR2410000A1 (fr) | 1979-06-22 |
| GB2009744B (en) | 1982-05-26 |
| CA1099265A (en) | 1981-04-14 |
| US4179438A (en) | 1979-12-18 |
| CH636619A5 (it) | 1983-06-15 |
| ZA786299B (en) | 1979-10-31 |
| AT360652B (de) | 1981-01-26 |
| DK155797B (da) | 1989-05-16 |
| GB2009744A (en) | 1979-06-20 |
| LU80567A1 (fr) | 1979-03-22 |
| GR71727B (es) | 1983-06-22 |
| FI65254C (fi) | 1984-04-10 |
| DK155797C (da) | 1989-10-02 |
| BE872294A (fr) | 1979-03-16 |
| ATA837078A (de) | 1980-06-15 |
| JPS625159B2 (es) | 1987-02-03 |
| DE2851312A1 (de) | 1979-07-12 |
| AR219775A1 (es) | 1980-09-15 |
| SE7812231L (sv) | 1979-05-30 |
| PT68840A (en) | 1978-12-01 |
| JPS5495599A (en) | 1979-07-28 |
| NL7811558A (nl) | 1979-05-31 |
| SE439168B (sv) | 1985-06-03 |
| AU519242B2 (en) | 1981-11-19 |
| FI65254B (fi) | 1983-12-30 |
| NO784005L (no) | 1979-05-30 |
| FI783639A (fi) | 1979-05-30 |
| YU279178A (en) | 1982-10-31 |
| IT1090759B (it) | 1985-06-26 |
| AU4186778A (en) | 1979-06-07 |
| DK530978A (da) | 1979-05-30 |
| FR2410000B1 (es) | 1983-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20100623 |