ES8104782A1 - Procedimiento de preparacion de nuevos derivados 1,1,2-tri- fenilpropanos y -propenos - Google Patents

Procedimiento de preparacion de nuevos derivados 1,1,2-tri- fenilpropanos y -propenos

Info

Publication number
ES8104782A1
ES8104782A1 ES494286A ES494286A ES8104782A1 ES 8104782 A1 ES8104782 A1 ES 8104782A1 ES 494286 A ES494286 A ES 494286A ES 494286 A ES494286 A ES 494286A ES 8104782 A1 ES8104782 A1 ES 8104782A1
Authority
ES
Spain
Prior art keywords
group
stand
phenyl
general formula
form together
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494286A
Other languages
English (en)
Spanish (es)
Other versions
ES494286A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of ES494286A0 publication Critical patent/ES494286A0/es
Publication of ES8104782A1 publication Critical patent/ES8104782A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/26—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton
    • C07C17/263—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions
    • C07C17/2635—Preparation of halogenated hydrocarbons by reactions involving an increase in the number of carbon atoms in the skeleton by condensation reactions involving a phosphorus compound, e.g. Wittig synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/35—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C07C17/354—Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction by hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/20—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/003—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by hydrogenation of an unsaturated part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
    • C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B22/00—Buoys
    • B63B2022/006—Buoys specially adapted for measuring or watch purposes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B63—SHIPS OR OTHER WATERBORNE VESSELS; RELATED EQUIPMENT
    • B63B—SHIPS OR OTHER WATERBORNE VESSELS; EQUIPMENT FOR SHIPPING 
    • B63B2211/00—Applications
    • B63B2211/02—Oceanography
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
ES494286A 1979-08-15 1980-08-14 Procedimiento de preparacion de nuevos derivados 1,1,2-tri- fenilpropanos y -propenos Expired ES8104782A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79GO1455A HU178253B (en) 1979-08-15 1979-08-15 Process for preparing 1,1,2-triphenyl-propane and -propane derivatives

Publications (2)

Publication Number Publication Date
ES494286A0 ES494286A0 (es) 1981-04-16
ES8104782A1 true ES8104782A1 (es) 1981-04-16

Family

ID=10996899

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494286A Expired ES8104782A1 (es) 1979-08-15 1980-08-14 Procedimiento de preparacion de nuevos derivados 1,1,2-tri- fenilpropanos y -propenos

Country Status (22)

Country Link
JP (1) JPS5668637A (show.php)
AT (1) AT372074B (show.php)
BE (1) BE884716A (show.php)
BG (3) BG35032A3 (show.php)
CA (1) CA1179359A (show.php)
CH (1) CH649758A5 (show.php)
CS (1) CS241030B2 (show.php)
DD (1) DD152536A5 (show.php)
DE (1) DE3030802A1 (show.php)
DK (1) DK351780A (show.php)
ES (1) ES8104782A1 (show.php)
FI (1) FI74271C (show.php)
FR (1) FR2463121B1 (show.php)
GB (1) GB2058061B (show.php)
GR (1) GR69821B (show.php)
HU (1) HU178253B (show.php)
IT (1) IT1228130B (show.php)
NL (1) NL8004542A (show.php)
PL (3) PL131226B1 (show.php)
SE (1) SE450250B (show.php)
SU (3) SU1253426A3 (show.php)
YU (2) YU42980B (show.php)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0175188A1 (de) * 1984-09-11 1986-03-26 Nihon Tokushu Noyaku Seizo K.K. Carbamoylimidazol-Derivate
US5681835A (en) * 1994-04-25 1997-10-28 Glaxo Wellcome Inc. Non-steroidal ligands for the estrogen receptor
WO1996014283A1 (en) * 1994-11-02 1996-05-17 EGIS Gyógyszergyár Rt. Process and intermediates for preparing triphenyltrifluoropropanes and -propenes
CN1275911A (zh) 1997-08-15 2000-12-06 杜克大学 一种预防或治疗雌激素依赖性疾病及失调的方法
CN1061334C (zh) * 1998-06-02 2001-01-31 中国科学院上海有机化学研究所 不饱和键三氟乙基化化合物的制备方法
US7935697B2 (en) * 2006-12-28 2011-05-03 Kinex Pharmaceuticals, Llc Compositions for modulating a kinase cascade and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637389A (show.php) * 1962-09-13
US3712929A (en) * 1969-10-31 1973-01-23 Du Pont 1-perfluoroalkyl-1,2,2-triphenylethylenes

Also Published As

Publication number Publication date
YU42980B (en) 1989-02-28
SU1253426A1 (ru) 1986-08-23
YU206880A (en) 1983-12-31
YU43182B (en) 1989-04-30
IT8024152A0 (it) 1980-08-14
SU1253426A3 (ru) 1986-08-23
CS241030B2 (en) 1986-03-13
PL131227B1 (en) 1984-10-31
BG35032A3 (bg) 1984-01-16
YU123983A (en) 1986-04-30
PL131226B1 (en) 1984-10-31
SE450250B (sv) 1987-06-15
BG35031A3 (bg) 1984-01-16
CA1179359A (en) 1984-12-11
GB2058061A (en) 1981-04-08
IT1228130B (it) 1991-05-28
ATA419280A (de) 1983-01-15
SU1097192A3 (ru) 1984-06-07
CS561680A2 (en) 1985-06-13
SU1114332A3 (ru) 1984-09-15
FR2463121A1 (fr) 1981-02-20
GB2058061B (en) 1983-07-20
PL226254A1 (en) 1983-01-17
NL8004542A (nl) 1981-02-17
BG34903A3 (bg) 1983-12-15
FI74271B (fi) 1987-09-30
PL238085A1 (en) 1983-04-11
ES494286A0 (es) 1981-04-16
HU178253B (en) 1982-04-28
BE884716A (fr) 1981-02-11
GR69821B (show.php) 1982-07-13
PL130386B1 (en) 1984-08-31
DE3030802A1 (de) 1981-03-12
SE8005688L (sv) 1981-02-16
JPH0234933B2 (show.php) 1990-08-07
DE3030802C2 (show.php) 1987-06-04
DD152536A5 (de) 1981-12-02
JPS5668637A (en) 1981-06-09
FI802584A7 (fi) 1981-02-16
CH649758A5 (de) 1985-06-14
AT372074B (de) 1983-08-25
DK351780A (da) 1981-02-16
FR2463121B1 (fr) 1987-01-02
FI74271C (fi) 1988-01-11

Similar Documents

Publication Publication Date Title
ES8603242A1 (es) Procedimiento para la obtencion de un derivado de nitrometi-leno
ES2059069T3 (es) Nuevos derivados de 1-alcoxi-(2-acilamino-etil)-naftalenos y su procedimiento de preparacion.
ES469953A1 (es) Un procedimiento para la preparacion de nuevos derivados de aminoalquilbenceno
ES521124A0 (es) Procedimiento para preparar espino (piperidino-oxobenzo-xazinas) substituidas en posicion 1 anti-hipertensivas.
SE8000205L (sv) Nya heterotricykliska derivat, sett for framstellning och anvendning derav sasom lekemedel samt farmaceutiska kompositioner innehallande dessa derivat
GB1369248A (en) Amides the preparation thereof and their use in pharmacjeutical compositions
CA2085796A1 (en) 3(2h)-pyridazinone derivatives and process for the preparation thereof
ES475173A1 (es) Procedimiento para la fabricacion de quinazolinas.
ES8104264A1 (es) Procedimiento para la preparacion de n- (trimetoxibencil)- n'-fenilpiperazinas
ES447011A1 (es) Procedimiento para preparar 1,1,1,-triaril-alquilaminas.
SE8005688L (sv) Nya 1,1,2-trifenylpropan-och-propenderivat, sett for deras framstellning och farmaceutiska beredningar innehallande dem
ES445367A1 (es) Procedimiento para la obtencion de derivados de tetralona e indanona.
SE7904358L (sv) Nya derivat av 4-amino-2-piperidinokinazolin
SE7704615L (sv) Sett att framstella nya 1,4-bensodioxanderivat
ES8500953A1 (es) Procedimiento para preparar derivados de tieno-tiazol
ES503093A0 (es) Procedimiento para preparar difenilbutil-1-acilpiperazinas
YU27291A (sh) Heterociklicne spojine
ES8107211A1 (es) Un procedimiento para la preparacion de nuevos derivados de benzoxocina.
ES478516A1 (es) Procedimiento para la preparacion de alfa-halometil amino acidos.
ES8504822A1 (es) Procedimiento para la preparacion de un nuevo derivado del pirrolo ortocondensado
SE8901060D0 (sv) New compounds
ES8603396A1 (es) Procedimiento para la obtencion de nuevos derivados de benzoilurea y productos intermedios
ES405645A1 (es) Procedimiento para la preparacion de nuevos acidos 4 - (4 -bifenilil) - 4 - hidroxi - butiricos, sus esteres o lacto- nas.
ES8201526A1 (es) Un procedimiento para la preparacion de nuevos derivados de 1,1'-binefil-2-il-alquilamina
ES469576A1 (es) Procedimiento para la preparacion de 5-alquilsulfonil- y 5- alquenilsulfonil-barbituricos.

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000301