ES478516A1 - Procedimiento para la preparacion de alfa-halometil amino acidos. - Google Patents
Procedimiento para la preparacion de alfa-halometil amino acidos.Info
- Publication number
- ES478516A1 ES478516A1 ES478516A ES478516A ES478516A1 ES 478516 A1 ES478516 A1 ES 478516A1 ES 478516 A ES478516 A ES 478516A ES 478516 A ES478516 A ES 478516A ES 478516 A1 ES478516 A1 ES 478516A1
- Authority
- ES
- Spain
- Prior art keywords
- hydrogen
- carbon atoms
- carbonyl
- alkyl
- phenylalanines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Procedimiento para la preparación de alfa halometil amino ácidos, de la siguiente estructura general **(Fórmula)** en que Y es FCH2-, F2CH-, ClCH2- ó Cl2CH;R1 es hidrógeno, alquilcarbonilo, en que la mitad de alquilo tiene de 1 a 4 átomos de carbono y es recta o ramificada, alcoxicarbonilo, en que la mitad alxoci tiene de 1 a 4 átomos de carbono y es recta o ramificada.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81424377A | 1977-07-11 | 1977-07-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES478516A1 true ES478516A1 (es) | 1979-07-16 |
Family
ID=25214519
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES471595A Expired ES471595A1 (es) | 1977-07-11 | 1978-07-10 | Procedimiento para la preparacion de alfa-halometil amino acidos |
| ES478517A Expired ES478517A1 (es) | 1977-07-11 | 1979-03-12 | Procedimiento para la preparacion de alfa-halometil amino a-cidos. |
| ES478516A Expired ES478516A1 (es) | 1977-07-11 | 1979-03-12 | Procedimiento para la preparacion de alfa-halometil amino acidos. |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES471595A Expired ES471595A1 (es) | 1977-07-11 | 1978-07-10 | Procedimiento para la preparacion de alfa-halometil amino acidos |
| ES478517A Expired ES478517A1 (es) | 1977-07-11 | 1979-03-12 | Procedimiento para la preparacion de alfa-halometil amino a-cidos. |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5484544A (es) |
| AU (1) | AU525684B2 (es) |
| BE (1) | BE868881A (es) |
| CH (1) | CH636846A5 (es) |
| DE (1) | DE2828738A1 (es) |
| DK (1) | DK309378A (es) |
| ES (3) | ES471595A1 (es) |
| FR (1) | FR2397391A1 (es) |
| GB (1) | GB2005659B (es) |
| IE (1) | IE46932B1 (es) |
| IL (1) | IL54913A0 (es) |
| IT (1) | IT1105534B (es) |
| NL (1) | NL7807454A (es) |
| NZ (1) | NZ187538A (es) |
| SE (1) | SE7807690L (es) |
| ZA (1) | ZA783273B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL59481A0 (en) * | 1977-07-11 | 1980-05-30 | Merrell Toraude & Co | -halomethyl amino acids |
| EP0007600B1 (en) * | 1978-07-24 | 1983-05-11 | Merck & Co. Inc. | Alpha-difluoromethyl amino acids and pharmaceutical composition containing the same |
| FR2450247A1 (fr) * | 1979-02-28 | 1980-09-26 | Tamsir Ndike Wade | Esters et acides aliphatiques a-amines b,b-difluores |
| IE49522B1 (en) * | 1979-04-26 | 1985-10-16 | Merrell Toraude & Co | Alpha-halomethylaminoacids |
| ZA813018B (en) * | 1980-05-09 | 1982-05-26 | Merrell Toraude & Co | Fluoromethylated tyrosine methyl ester |
| ZA815807B (en) * | 1980-08-23 | 1982-08-25 | Merrell Toraude & Co | Preparation of aminoacetonitrile derivatives |
| CN113383391A (zh) * | 2018-12-06 | 2021-09-10 | 先达生物科技公司 | 季铵盐作为三甲胺产生的抑制剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3046300A (en) * | 1960-10-21 | 1962-07-24 | Merck & Co Inc | alpha-trifluoromethyloxyphenylalanines |
| IE47542B1 (en) * | 1977-06-01 | 1984-04-18 | Merck & Co Inc | Di-and tri-fluoromethyl amino acids and amines,compositions and processes for preparing said compounds |
| GR64495B (en) * | 1977-06-01 | 1980-03-31 | Merck & Co Inc | Novel fluorinated amino acids |
-
1978
- 1978-06-07 ZA ZA00783273A patent/ZA783273B/xx unknown
- 1978-06-08 IE IE1167/78A patent/IE46932B1/en not_active IP Right Cessation
- 1978-06-13 NZ NZ187538A patent/NZ187538A/en unknown
- 1978-06-15 IL IL7854913A patent/IL54913A0/xx not_active IP Right Cessation
- 1978-06-21 AU AU37312/78A patent/AU525684B2/en not_active Expired
- 1978-06-27 GB GB7827966A patent/GB2005659B/en not_active Expired
- 1978-06-30 DE DE19782828738 patent/DE2828738A1/de not_active Withdrawn
- 1978-07-07 CH CH742978A patent/CH636846A5/de not_active IP Right Cessation
- 1978-07-08 JP JP8253178A patent/JPS5484544A/ja active Granted
- 1978-07-10 FR FR7820516A patent/FR2397391A1/fr active Granted
- 1978-07-10 SE SE7807690A patent/SE7807690L/xx unknown
- 1978-07-10 ES ES471595A patent/ES471595A1/es not_active Expired
- 1978-07-10 BE BE189190A patent/BE868881A/xx not_active IP Right Cessation
- 1978-07-10 DK DK783093A patent/DK309378A/da unknown
- 1978-07-10 IT IT50230/78A patent/IT1105534B/it active
- 1978-07-11 NL NL7807454A patent/NL7807454A/xx not_active Application Discontinuation
-
1979
- 1979-03-12 ES ES478517A patent/ES478517A1/es not_active Expired
- 1979-03-12 ES ES478516A patent/ES478516A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH636846A5 (de) | 1983-06-30 |
| ZA783273B (en) | 1979-06-27 |
| DE2828738A1 (de) | 1979-02-01 |
| IT7850230A0 (it) | 1978-07-10 |
| DK309378A (da) | 1979-01-12 |
| SE7807690L (sv) | 1979-01-12 |
| ES471595A1 (es) | 1979-10-01 |
| FR2397391B1 (es) | 1981-02-20 |
| BE868881A (fr) | 1978-11-03 |
| GB2005659B (en) | 1982-02-17 |
| IT1105534B (it) | 1985-11-04 |
| NL7807454A (nl) | 1979-01-15 |
| GB2005659A (en) | 1979-04-25 |
| IE46932B1 (en) | 1983-11-02 |
| FR2397391A1 (fr) | 1979-02-09 |
| JPS6326101B2 (es) | 1988-05-27 |
| AU3731278A (en) | 1980-01-03 |
| JPS5484544A (en) | 1979-07-05 |
| AU525684B2 (en) | 1982-11-25 |
| IL54913A0 (en) | 1978-08-31 |
| IE781167L (en) | 1979-01-11 |
| NZ187538A (en) | 1982-08-17 |
| ES478517A1 (es) | 1979-07-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |