GB2001061A - alpha -Vinyl Amino Acids - Google Patents

alpha -Vinyl Amino Acids

Info

Publication number
GB2001061A
GB2001061A GB7828005A GB7828005A GB2001061A GB 2001061 A GB2001061 A GB 2001061A GB 7828005 A GB7828005 A GB 7828005A GB 7828005 A GB7828005 A GB 7828005A GB 2001061 A GB2001061 A GB 2001061A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
carbon atoms
carbonyl
alkyl
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB7828005A
Other versions
GB2001061B (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merrell Toraude et Cie
Original Assignee
Merrell Toraude et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude et Cie filed Critical Merrell Toraude et Cie
Publication of GB2001061A publication Critical patent/GB2001061A/en
Application granted granted Critical
Publication of GB2001061B publication Critical patent/GB2001061B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Pharmaceutically useful compounds have the formula <IMAGE> and pharmaceutically acceptable salts and individual optical isomers thereof, wherein R1 is hydrogen, (C1-4alkyl) carbonyl (C1-4alkoxy) carbonyl or CO-CHNH2-R17 wherein R17 is hydrogen, alkyl of 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; R is hydroxy, alkoxy of 1 to 8 carbon atoms, -NR7R8 wherein R7 and R8 are the same or different and are each hydrogen or alkyl or 1 to 4 carbon atoms or -NH-CHR9COOH wherein R9 is hydrogen, alkyl of 1 to 4 carbon atoms, benzyl or p-hydroxybenzyl; and R2, R3, R4, R5 and R6 are certain combinations of hydrogen, methyl, ethyl, tert-butyl, chlorine, fluorine and OR10 wherein R10 is hydrogen, alkyl of 1 to 8 carbon atoms, (C1-6alkyl) carbonyl, benzoyl or phenyl(C1-6alkyl)-carbonyl.
GB7828005A 1977-07-01 1978-06-27 -vincly amino acids Expired GB2001061B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81226477A 1977-07-01 1977-07-01

Publications (2)

Publication Number Publication Date
GB2001061A true GB2001061A (en) 1979-01-24
GB2001061B GB2001061B (en) 1982-02-24

Family

ID=25209049

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7828005A Expired GB2001061B (en) 1977-07-01 1978-06-27 -vincly amino acids

Country Status (7)

Country Link
JP (1) JPS5416443A (en)
BE (1) BE868593A (en)
CA (1) CA1157030A (en)
DE (1) DE2827805A1 (en)
FR (1) FR2395984A1 (en)
GB (1) GB2001061B (en)
ZA (1) ZA783275B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007615A2 (en) * 1978-07-24 1980-02-06 Merck & Co. Inc. Process for preparing amino acids and esters
GB2188047A (en) * 1986-03-04 1987-09-23 Toyo Jozo Kk Aldose reductase inhibitors

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK309679A (en) * 1978-07-24 1980-02-22 Merck & Co Inc PROCESS FOR THE PREPARATION OF ALFAVINYLAMINO ACIDS AND ESTERS THEREOF
NL2028207B1 (en) 2021-05-12 2022-11-30 Flint Group Germany Gmbh A relief precursor with vegetable oils as plasticizers suitable for printing plates
NL2028208B1 (en) 2021-05-12 2022-11-30 Flint Group Germany Gmbh Flexographic printing element precursor with high melt flow index

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3960927A (en) * 1975-03-18 1976-06-01 Richardson-Merrell Inc. Olefinic derivatives of amino acids
US4401676A (en) * 1977-06-01 1983-08-30 Merck & Co., Inc. Novel α-amino acids

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0007615A2 (en) * 1978-07-24 1980-02-06 Merck & Co. Inc. Process for preparing amino acids and esters
EP0007615A3 (en) * 1978-07-24 1980-05-28 Merck & Co. Inc. Process for preparing amino acids and esters, and intermediates therefor
GB2188047A (en) * 1986-03-04 1987-09-23 Toyo Jozo Kk Aldose reductase inhibitors
US4749571A (en) * 1986-03-04 1988-06-07 Toyo Jozo Co., Ltd. Physiologically-active novel substance "Aldostatin" and production method thereof
GB2188047B (en) * 1986-03-04 1989-12-28 Toyo Jozo Kk Aldose reductase inhibitor

Also Published As

Publication number Publication date
ZA783275B (en) 1979-06-27
DE2827805A1 (en) 1979-01-18
GB2001061B (en) 1982-02-24
FR2395984B1 (en) 1981-09-04
CA1157030A (en) 1983-11-15
FR2395984A1 (en) 1979-01-26
JPS5416443A (en) 1979-02-07
BE868593A (en) 1978-10-16
JPS6338345B2 (en) 1988-07-29

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19940627