ES8104411A1 - Un procedimiento para la preparacion del complejo antitumo- ral bbm-928 - Google Patents

Un procedimiento para la preparacion del complejo antitumo- ral bbm-928

Info

Publication number
ES8104411A1
ES8104411A1 ES490209A ES490209A ES8104411A1 ES 8104411 A1 ES8104411 A1 ES 8104411A1 ES 490209 A ES490209 A ES 490209A ES 490209 A ES490209 A ES 490209A ES 8104411 A1 ES8104411 A1 ES 8104411A1
Authority
ES
Spain
Prior art keywords
bbm
antitumor
complex
against gram
antibacterial agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490209A
Other languages
English (en)
Other versions
ES490209A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8104411A1 publication Critical patent/ES8104411A1/es
Publication of ES490209A0 publication Critical patent/ES490209A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DEL COMPLEJO ANTITUMORAL BBM-928 Y DE SUS COMPONENTES A, B, C, D, E Y F. CONSISTE EN CULTIVAR LA CEPA DE ACTINOMICETOS CON LAS CARACTERISTICAS DE LA CEPA NUMERO G455-101 EN UNA SOLUCION ACUOSA QUE CONTIENE FUENTES DE CARBONO Y NITROGENO ASIMILABLES, EN CONDICIONES AEROBICAS SUMERGIDAS, HASTA QUE EL COMPLEJO BBM-928 PRODUCIDO COMUNICA A DICHA SOLUCION UNA ACTIVIDAD ANTIBIOTICA ANTITUMORAL SUSTANCIAL. POSTERIORMENTE, MEDIANTE METODOS ADECUADOS, SE SEPARA EL COMPLEJO BBM-928 DEL CULTIVO Y, OPCIONALMENTE, SE PUEDEN SEPARAR SUS COMPONENTES. LOS COMPONENTES BIOACTIVOS DEL COMPLEJO EJERCEN UNA PRONUNCIADA ACTIVIDAD ANTITUMORAL Y SON DEBILMENTE ACTIVOS CONTRA LAS BACTERIAS GRAM-POSITIVAS Y FIJAS A LOS ACIDOS, PERO PRACTICAMENTE INACTIVOS CONTRA LAS BACTERIAS GRAM-NEGATIVAS Y HONGOS.
ES490209A 1979-04-02 1980-04-01 Un procedimiento para la preparacion del complejo antitumo- ral bbm-928 Granted ES490209A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2648879A 1979-04-02 1979-04-02

Publications (2)

Publication Number Publication Date
ES8104411A1 true ES8104411A1 (es) 1981-04-16
ES490209A0 ES490209A0 (es) 1981-04-16

Family

ID=21832125

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490209A Granted ES490209A0 (es) 1979-04-02 1980-04-01 Un procedimiento para la preparacion del complejo antitumo- ral bbm-928

Country Status (24)

Country Link
JP (3) JPS55162752A (es)
AR (1) AR223372A1 (es)
AT (1) AT371144B (es)
AU (1) AU533672B2 (es)
BE (1) BE882574A (es)
CH (1) CH647247A5 (es)
DE (1) DE3012565A1 (es)
DK (1) DK153501C (es)
ES (1) ES490209A0 (es)
FI (1) FI67403C (es)
FR (1) FR2452930A1 (es)
GB (1) GB2050384B (es)
GR (1) GR66663B (es)
HU (1) HU184256B (es)
IE (1) IE49191B1 (es)
IL (1) IL59746A (es)
LU (1) LU82318A1 (es)
NL (1) NL8001868A (es)
NO (1) NO155780C (es)
PH (1) PH16970A (es)
SE (1) SE441930B (es)
SU (1) SU999981A3 (es)
YU (1) YU41700B (es)
ZA (1) ZA801856B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4416874A (en) 1982-03-05 1983-11-22 Bristol-Myers Company Injectable compositions of BBM-928A
AU566569B2 (en) * 1983-01-31 1987-10-22 Bristol-Myers Company Luzopeptin e2
ATE31623T1 (de) * 1983-09-14 1988-01-15 Bristol Myers Co Injizierbare zusammensetzungen von bbm-928a.
US6749993B2 (en) 2002-02-06 2004-06-15 Konica Corporation Planographic printing precursor and printing method employing the same
JP2003300382A (ja) 2002-04-08 2003-10-21 Konica Minolta Holdings Inc 熱転写中間転写媒体を用いた画像形成方法
JP2004188848A (ja) 2002-12-12 2004-07-08 Konica Minolta Holdings Inc 印刷版材料
JP2004322511A (ja) 2003-04-25 2004-11-18 Konica Minolta Medical & Graphic Inc 印刷方法
JP2006056184A (ja) 2004-08-23 2006-03-02 Konica Minolta Medical & Graphic Inc 印刷版材料および印刷版
EP1944174A1 (en) 2005-11-01 2008-07-16 Konica Minolta Medical & Graphic, Inc. Lithographic printing plate material, lithographic printing plate, method for preparing lithographic printing plate, and method for printing by lithographic printing plate
JP4878612B2 (ja) * 2008-07-16 2012-02-15 スタンレー電気株式会社 車両用信号灯具
US9052217B2 (en) 2012-11-09 2015-06-09 Honeywell International Inc. Variable scale sensor

Also Published As

Publication number Publication date
JPS63139191A (ja) 1988-06-10
DE3012565C2 (es) 1990-11-08
JPS6365679B2 (es) 1988-12-16
IE49191B1 (en) 1985-08-21
LU82318A1 (fr) 1980-12-16
AT371144B (de) 1983-06-10
YU41700B (en) 1987-12-31
JPH0341475B2 (es) 1991-06-24
FR2452930B1 (es) 1983-12-30
NO155780B (no) 1987-02-16
NL8001868A (nl) 1980-10-06
ZA801856B (en) 1981-04-29
AR223372A1 (es) 1981-08-14
AU533672B2 (en) 1983-12-08
AU5700280A (en) 1980-10-09
YU81280A (en) 1983-09-30
PH16970A (en) 1984-04-27
GB2050384A (en) 1981-01-07
NO155780C (no) 1987-05-27
JPS63139192A (ja) 1988-06-10
ATA180380A (de) 1982-10-15
GR66663B (es) 1981-04-07
DE3012565A1 (de) 1980-10-23
GB2050384B (en) 1983-04-07
CH647247A5 (fr) 1985-01-15
DK153501C (da) 1988-11-28
SE8002521L (sv) 1980-10-03
IL59746A (en) 1983-02-23
ES490209A0 (es) 1981-04-16
IL59746A0 (en) 1980-06-30
DK138780A (da) 1980-10-03
SU999981A3 (ru) 1983-02-23
IE800598L (en) 1980-10-02
JPH0341157B2 (es) 1991-06-21
HU184256B (en) 1984-07-30
DK153501B (da) 1988-07-18
FI67403C (fi) 1985-03-11
NO800967L (no) 1980-10-03
FI800973A (fi) 1980-10-03
SE441930B (sv) 1985-11-18
FR2452930A1 (fr) 1980-10-31
FI67403B (fi) 1984-11-30
JPS55162752A (en) 1980-12-18
BE882574A (fr) 1980-10-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401