ES8102147A1 - Procedimiento para la obtencion de derivados de sisomicina - Google Patents

Procedimiento para la obtencion de derivados de sisomicina

Info

Publication number
ES8102147A1
ES8102147A1 ES491960A ES491960A ES8102147A1 ES 8102147 A1 ES8102147 A1 ES 8102147A1 ES 491960 A ES491960 A ES 491960A ES 491960 A ES491960 A ES 491960A ES 8102147 A1 ES8102147 A1 ES 8102147A1
Authority
ES
Spain
Prior art keywords
derivatives
medicines
preparation
sisomicin derivatives
sisomycin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491960A
Other languages
English (en)
Other versions
ES491960A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES491960A0 publication Critical patent/ES491960A0/es
Publication of ES8102147A1 publication Critical patent/ES8102147A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • C07H15/236—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2 a saccharide radical being substituted by an alkylamino radical in position 3 and by two substituents different from hydrogen in position 4, e.g. gentamicin complex, sisomicin, verdamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE SISOMICINA DE FORMULA; *FORMULA* DONDE X, R1, R2 SON DISTINTOS TIPOS DE RADICALES. SU OBTENCION DEPENDE DE LAS MULTIPLES VARIACIONES DE COLOCACION DE LOS RADICALES. LAS TEMPERATURAS DE REACCION ESTAN COMPRENDIDAS ENTRE 0 Y 40GC. LA REACCION SE PUEDE REALIZAR A PRESION NORMAL. EN LA OBTENCION DE ESTOS DERIVADOS SE EMPLEAN AGENTES DE RECUCCION DONADORES DE HIDROGENO Y EN PRESENCIA DE UN DISOLVENTE INERTE. ESTOS DERIVADOS TIENEN PROPIEDADES ANTIBACTERICIDAS. ,
ES491960A 1979-05-30 1980-05-29 Procedimiento para la obtencion de derivados de sisomicina Expired ES8102147A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792921973 DE2921973A1 (de) 1979-05-30 1979-05-30 Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (2)

Publication Number Publication Date
ES491960A0 ES491960A0 (es) 1980-12-16
ES8102147A1 true ES8102147A1 (es) 1980-12-16

Family

ID=6072057

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491960A Expired ES8102147A1 (es) 1979-05-30 1980-05-29 Procedimiento para la obtencion de derivados de sisomicina

Country Status (8)

Country Link
US (1) US4312859A (es)
EP (1) EP0019843B1 (es)
JP (1) JPS55160791A (es)
AT (1) ATE1609T1 (es)
CA (1) CA1141759A (es)
DE (2) DE2921973A1 (es)
DK (1) DK230580A (es)
ES (1) ES8102147A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3101376A1 (de) 1981-01-17 1982-09-02 Bayer Ag, 5090 Leverkusen Sisomicin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US5079234A (en) * 1989-03-23 1992-01-07 Bristol-Myers Squibb Co. Inhibitors of aminoglycoside nephrotoxicity
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
EP3150617B1 (en) 2007-11-21 2020-04-08 Cipla USA, Inc. Antibacterial aminoglycoside analogs
WO2010132757A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132765A2 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial aminoglycoside analogs
WO2010132760A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of tobramycin
WO2010132768A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of sisomicin
WO2010132759A1 (en) 2009-05-15 2010-11-18 Achaogen, Inc. Antibacterial derivatives of dibekacin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5324415B2 (es) * 1972-10-06 1978-07-20
US3965089A (en) * 1973-03-12 1976-06-22 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Process for the production of a cyclic ureido-derivative of a deoxystreptamine-containing antibiotic and products thereof
PH12960A (en) * 1974-03-19 1979-10-19 Scherico Ltd Derivatives of 4,6-di-(aminoglycosyl)-1,3-diaminocy-clitols and pharmaceutical compositions thereof
AR207582A1 (es) * 1974-03-19 1976-10-15 Scherico Ltd Procedimiento para preparar derivados de diaminociclitole
JPS51127045A (en) * 1975-04-24 1976-11-05 Microbial Chem Res Found A process for preparing 3'- deoxykanamycin a derivatives.
DE2832268A1 (de) * 1978-07-22 1980-01-31 Bayer Ag Pseudotrisaccharide

Also Published As

Publication number Publication date
ES491960A0 (es) 1980-12-16
DE3060897D1 (en) 1982-11-11
US4312859A (en) 1982-01-26
JPS55160791A (en) 1980-12-13
CA1141759A (en) 1983-02-22
DE2921973A1 (de) 1980-12-11
EP0019843B1 (de) 1982-09-29
EP0019843A1 (de) 1980-12-10
ATE1609T1 (de) 1982-10-15
DK230580A (da) 1980-12-01

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