ES8201141A1 - Procedimiento para preparar derivados de s-fenilseleno-bencimidazol. - Google Patents
Procedimiento para preparar derivados de s-fenilseleno-bencimidazol.Info
- Publication number
- ES8201141A1 ES8201141A1 ES495828A ES495828A ES8201141A1 ES 8201141 A1 ES8201141 A1 ES 8201141A1 ES 495828 A ES495828 A ES 495828A ES 495828 A ES495828 A ES 495828A ES 8201141 A1 ES8201141 A1 ES 8201141A1
- Authority
- ES
- Spain
- Prior art keywords
- fasciolicidal
- derivatives
- anthelmintic
- phenylselenobenzimidazole
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C391/00—Compounds containing selenium
- C07C391/02—Compounds containing selenium having selenium atoms bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
- C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 5-FENILSELENOBENCIMIDAZOL, DE FORMULA (I), DONDE R1 ES UN RADICAL ALQUILO; R2 ES UN RADICAL FENILO, CON UNO O MAS SUSTITUYENTES, Y N ES 0, 1 O 2. CONSISTE EN HACER REACCIONAR UNA DIAMIDA DE FORMULA (II) CON CIANAMIDA O UNA 2-(ALQUILO)ISOTIOUREA, Y UN CLOROFORMIATO DE ALQUILO, O UN CARBONATO DE DIALQUILO. EN TODOS LOS CASOS, LOS RADICALES ALQUILO CONTIENEN DE 1 A 6 ATOMOS DE CARBONO. EXISTEN COMO ALTERNATIVA, OTROS COMPUESTOS CON LOS QUE SE PUEDE HACER REACCIONAR LA DIAMIDA DE FORMULA (II). DE APLICACION POR SU ACTIVIDAD ANTIHELMINTICA Y FASCIOLITICA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7935502 | 1979-10-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES495828A0 ES495828A0 (es) | 1981-12-01 |
ES8201141A1 true ES8201141A1 (es) | 1982-01-16 |
Family
ID=10508467
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES495828A Expired ES8201141A1 (es) | 1979-10-12 | 1980-10-10 | Procedimiento para preparar derivados de s-fenilseleno-bencimidazol. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4303666A (es) |
EP (1) | EP0028455A1 (es) |
JP (1) | JPS5661363A (es) |
AU (1) | AU6293380A (es) |
CA (1) | CA1153381A (es) |
CS (1) | CS215073B2 (es) |
DK (1) | DK422980A (es) |
ES (1) | ES8201141A1 (es) |
NZ (1) | NZ195096A (es) |
YU (1) | YU259380A (es) |
ZA (1) | ZA806020B (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103601684B (zh) * | 2013-11-29 | 2016-01-20 | 沈阳药科大学 | 5-芳硒基苯并咪唑类化合物及其用途 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE793358A (fr) * | 1971-12-27 | 1973-06-27 | Hoechst Ag | Nouveaux derives de 2-carbalcoxy-amino-benzimidazole presentantune activite anthelmintique et leur procede de preparation |
US3965113A (en) * | 1972-12-29 | 1976-06-22 | Syntex (U.S.A.) Inc. | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3929824A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity |
US3929821A (en) * | 1972-12-29 | 1975-12-30 | Syntex Inc | 5 (6)-Benzene ring substituted benzimidazole-2-carbamate derivatives |
DE2365362A1 (de) * | 1973-06-25 | 1975-01-23 | Hoechst Ag | 2,1,4-benzothiadiazinderivate und ihre herstellung |
DE2332343A1 (de) * | 1973-06-26 | 1975-01-16 | Hoechst Ag | 2-carbalkoxy-amino-benzimidazol-5(6)phenylaether, ihre herstellung und verwendung in mitteln gegen helminthen |
DE2332398A1 (de) * | 1973-06-26 | 1975-01-23 | Hoechst Ag | 2-carbalkoxy-amino-benzimidazol-5(6)phenylaether, ihre herstellung und verwendung in mitteln gegen helminthen |
DE2432631A1 (de) * | 1974-07-06 | 1976-01-22 | Hoechst Ag | 5-phenylsulfinyl-2-benzimidazol-carbaminsaeureester und verfahren zu ihrer herstellung |
DE2438120A1 (de) * | 1974-08-08 | 1976-02-19 | Bayer Ag | Substituierte benzimidazolylcarbamidsaeureester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
YU40704B (en) * | 1977-05-10 | 1986-04-30 | Chinoin Gyogyszer Es Vegyeszet | Process for obtaininga 5(6)-thiobenzamidazole derivatives |
-
1980
- 1980-09-26 EP EP80303401A patent/EP0028455A1/en not_active Ceased
- 1980-09-29 ZA ZA00806020A patent/ZA806020B/xx unknown
- 1980-09-30 NZ NZ195096A patent/NZ195096A/xx unknown
- 1980-10-03 AU AU62933/80A patent/AU6293380A/en not_active Abandoned
- 1980-10-07 US US06/194,932 patent/US4303666A/en not_active Expired - Lifetime
- 1980-10-07 DK DK422980A patent/DK422980A/da not_active Application Discontinuation
- 1980-10-09 YU YU02593/80A patent/YU259380A/xx unknown
- 1980-10-09 CS CS806831A patent/CS215073B2/cs unknown
- 1980-10-10 ES ES495828A patent/ES8201141A1/es not_active Expired
- 1980-10-10 CA CA000362239A patent/CA1153381A/en not_active Expired
- 1980-10-13 JP JP14215380A patent/JPS5661363A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
YU259380A (en) | 1983-02-28 |
JPS5661363A (en) | 1981-05-26 |
US4303666A (en) | 1981-12-01 |
CA1153381A (en) | 1983-09-06 |
ES495828A0 (es) | 1981-12-01 |
ZA806020B (en) | 1981-11-25 |
AU6293380A (en) | 1981-04-16 |
CS215073B2 (en) | 1982-07-30 |
DK422980A (da) | 1981-04-13 |
NZ195096A (en) | 1982-12-21 |
EP0028455A1 (en) | 1981-05-13 |
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