ES523344A0 - Un procedimiento de preparacion de derivados de bencimidazol (divisional de la patente de invencion num. 514.947, presentada el 12 de agosto 1982) - Google Patents

Un procedimiento de preparacion de derivados de bencimidazol (divisional de la patente de invencion num. 514.947, presentada el 12 de agosto 1982)

Info

Publication number
ES523344A0
ES523344A0 ES523344A ES523344A ES523344A0 ES 523344 A0 ES523344 A0 ES 523344A0 ES 523344 A ES523344 A ES 523344A ES 523344 A ES523344 A ES 523344A ES 523344 A0 ES523344 A0 ES 523344A0
Authority
ES
Spain
Prior art keywords
carbon atoms
group
preparation
divisional
august
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES523344A
Other languages
English (en)
Other versions
ES8500265A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hassle AB
Original Assignee
Hassle AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hassle AB filed Critical Hassle AB
Publication of ES523344A0 publication Critical patent/ES523344A0/es
Publication of ES8500265A1 publication Critical patent/ES8500265A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES523344A 1981-08-13 1983-06-16 Un procedimiento de preparacion de derivados de bencimidazol (divisional de la patente de invencion num. 514.947, presentada el 12 de agosto 1982) Expired ES8500265A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8104811 1981-08-13

Publications (2)

Publication Number Publication Date
ES523344A0 true ES523344A0 (es) 1984-10-01
ES8500265A1 ES8500265A1 (es) 1984-10-01

Family

ID=20344360

Family Applications (3)

Application Number Title Priority Date Filing Date
ES514947A Expired ES8401482A1 (es) 1981-08-13 1982-08-12 "un procedimiento de preparacion de derivados de bencimidazol".
ES523344A Expired ES8500265A1 (es) 1981-08-13 1983-06-16 Un procedimiento de preparacion de derivados de bencimidazol (divisional de la patente de invencion num. 514.947, presentada el 12 de agosto 1982)
ES532044A Granted ES532044A0 (es) 1981-08-13 1984-04-30 Un procedimiento de preparacion de derivados de bencimidazol.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES514947A Expired ES8401482A1 (es) 1981-08-13 1982-08-12 "un procedimiento de preparacion de derivados de bencimidazol".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES532044A Granted ES532044A0 (es) 1981-08-13 1984-04-30 Un procedimiento de preparacion de derivados de bencimidazol.

Country Status (27)

Country Link
US (1) US4746667A (es)
EP (1) EP0074341B1 (es)
JP (1) JPS5839622A (es)
KR (1) KR880001714B1 (es)
AT (1) ATE18765T1 (es)
AU (1) AU556736B2 (es)
CA (1) CA1226223A (es)
CS (1) CS249124B2 (es)
CY (1) CY1450A (es)
DD (1) DD202876A5 (es)
DE (1) DE3270116D1 (es)
DK (1) DK362482A (es)
ES (3) ES8401482A1 (es)
FI (1) FI822813L (es)
GR (1) GR76267B (es)
HK (1) HK2189A (es)
HU (1) HU190408B (es)
IE (1) IE54215B1 (es)
IL (1) IL66340A (es)
IS (1) IS1360B6 (es)
MY (1) MY8700139A (es)
NO (1) NO822686L (es)
NZ (1) NZ201538A (es)
OA (1) OA07182A (es)
PH (1) PH18635A (es)
PT (1) PT75420B (es)
ZA (1) ZA825106B (es)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
CA1259070A (en) * 1983-07-01 1989-09-05 Upjohn Company (The) Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl|-benzimidazoles
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8404065D0 (sv) * 1984-08-10 1984-08-10 Haessle Ab Novel biologically active compounds
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
GB8526154D0 (en) * 1985-02-06 1985-11-27 Kotobuki Seiyaku Co Ltd 2-substituted cyclo-heptoimidazoles
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
AR243167A1 (es) * 1985-08-24 1993-07-30 Hoechst Ag Procedimiento para la preparacion de toluidinas sustituidas.
EP0786461A1 (en) * 1986-11-13 1997-07-30 Eisai Co., Ltd. Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
JP2718945B2 (ja) * 1987-06-17 1998-02-25 エーザイ株式会社 ピリジン誘導体及びそれを含有する潰瘍治療剤
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
US5223515A (en) * 1988-08-18 1993-06-29 Takeda Chemical Industries, Ltd. Injectable solution containing a pyridyl methylsulfinylbenzimidazole
AT394368B (de) * 1990-08-07 1992-03-25 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung von 3,4-dialkoxypyridinen
EP0644191A1 (en) * 1992-06-01 1995-03-22 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and medicinal use thereof
WO1995011897A1 (fr) * 1993-10-29 1995-05-04 Yoshitomi Pharmaceutical Industries, Ltd. Compose de pyridine et son utilisation en tant que remede
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions
US5387600A (en) * 1992-07-30 1995-02-07 Fuji Photo Film Co., Ltd. Treating arteriosclerosis using benzimidazole compositions
JP3559045B2 (ja) 1994-06-10 2004-08-25 ナウチノ−イススレドバテルスキ インスティテュト ファルマコロギイ ロスシイスコイ アカデミイ メディツィンスキフ ナウク 薬理学的活性を有する２−メルカプトベンズイミダゾール誘導体
US7230014B1 (en) 1997-10-14 2007-06-12 Eisai Co., Ltd. Pharmaceutical formulation comprising glycine as a stabilizer
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
DE10140492A1 (de) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
KR101276915B1 (ko) 2004-09-13 2013-06-19 다케다 야쿠힌 고교 가부시키가이샤 산화 화합물 제조 방법 및 제조 장치
US20090143438A1 (en) 2006-03-10 2009-06-04 Arigen Pharmaceuticals, Inc. Novel Pyridine Derivative Having Anti-Helicobacter Pylori Activity
EP2086543A2 (en) 2006-10-27 2009-08-12 The Curators of the University of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
PT2103608E (pt) 2006-12-18 2012-09-24 Arigen Pharmaceuticals Inc Agente de erradicação de helicobacter pylori possuindo uma actividade inibidora na secreção de ácido gástrico
JP2011512416A (ja) 2008-02-20 2011-04-21 ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリ オメプラゾール及びランソプラゾールの組合せと緩衝剤を含んでなる組成物とそれを使用する方法
KR101353572B1 (ko) * 2009-04-09 2014-01-22 링크 제노믹스 가부시키가이샤 피리딘티오 유도체 및 이를 함유하는 항-헬리코박터피로리 작용을 가지는 의약 조성물
US8722026B2 (en) 2010-01-06 2014-05-13 Elc Management, Llc Skin lightening compositions
US8992897B2 (en) * 2010-01-06 2015-03-31 Elc Management Llc Skin lightening compositions
AU2013267022B2 (en) * 2010-01-06 2016-04-21 Elc Management Llc Skin lightening compositions
WO2018053161A1 (en) * 2016-09-14 2018-03-22 National Taiwan University Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7112208A (es) * 1971-09-04 1973-03-06
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (es) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects

Also Published As

Publication number Publication date
ES514947A0 (es) 1983-12-16
CA1226223A (en) 1987-09-01
AU556736B2 (en) 1986-11-20
DD202876A5 (de) 1983-10-05
PT75420B (en) 1986-12-09
IS1360B6 (is) 1989-05-25
ES8502109A1 (es) 1984-12-16
KR840001156A (ko) 1984-03-28
PT75420A (en) 1982-09-01
DE3270116D1 (en) 1986-04-30
CS249124B2 (en) 1987-03-12
DK362482A (da) 1983-02-14
JPS5839622A (ja) 1983-03-08
HU190408B (en) 1986-09-29
ES532044A0 (es) 1984-12-16
FI822813L (fi) 1983-02-14
HK2189A (en) 1989-01-20
IE54215B1 (en) 1989-07-19
JPH0313203B2 (es) 1991-02-22
FI822813A0 (fi) 1982-08-12
NZ201538A (en) 1985-12-13
GR76267B (es) 1984-08-04
ES8401482A1 (es) 1983-12-16
KR880001714B1 (ko) 1988-09-08
PH18635A (en) 1985-08-23
ZA825106B (en) 1983-04-27
IE821940L (en) 1983-02-13
OA07182A (fr) 1984-04-30
ATE18765T1 (de) 1986-04-15
EP0074341B1 (en) 1986-03-26
MY8700139A (en) 1987-12-31
IL66340A (en) 1986-08-31
IL66340A0 (en) 1982-11-30
EP0074341A1 (en) 1983-03-16
CY1450A (en) 1989-03-10
NO822686L (no) 1983-02-14
US4746667A (en) 1988-05-24
ES8500265A1 (es) 1984-10-01
IS2749A7 (is) 1983-02-14
AU8697882A (en) 1983-02-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990401