IL66340A - Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation - Google Patents

Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation

Info

Publication number
IL66340A
IL66340A IL66340A IL6634082A IL66340A IL 66340 A IL66340 A IL 66340A IL 66340 A IL66340 A IL 66340A IL 6634082 A IL6634082 A IL 6634082A IL 66340 A IL66340 A IL 66340A
Authority
IL
Israel
Prior art keywords
derivatives
carbon atoms
group
preparation
pyridylmethyl
Prior art date
Application number
IL66340A
Other languages
English (en)
Other versions
IL66340A0 (en
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of IL66340A0 publication Critical patent/IL66340A0/xx
Publication of IL66340A publication Critical patent/IL66340A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
IL66340A 1981-08-13 1982-07-16 Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation IL66340A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8104811 1981-08-13

Publications (2)

Publication Number Publication Date
IL66340A0 IL66340A0 (en) 1982-11-30
IL66340A true IL66340A (en) 1986-08-31

Family

ID=20344360

Family Applications (1)

Application Number Title Priority Date Filing Date
IL66340A IL66340A (en) 1981-08-13 1982-07-16 Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation

Country Status (27)

Country Link
US (1) US4746667A (xx)
EP (1) EP0074341B1 (xx)
JP (1) JPS5839622A (xx)
KR (1) KR880001714B1 (xx)
AT (1) ATE18765T1 (xx)
AU (1) AU556736B2 (xx)
CA (1) CA1226223A (xx)
CS (1) CS249124B2 (xx)
CY (1) CY1450A (xx)
DD (1) DD202876A5 (xx)
DE (1) DE3270116D1 (xx)
DK (1) DK362482A (xx)
ES (3) ES514947A0 (xx)
FI (1) FI822813L (xx)
GR (1) GR76267B (xx)
HK (1) HK2189A (xx)
HU (1) HU190408B (xx)
IE (1) IE54215B1 (xx)
IL (1) IL66340A (xx)
IS (1) IS1360B6 (xx)
MY (1) MY8700139A (xx)
NO (1) NO822686L (xx)
NZ (1) NZ201538A (xx)
OA (1) OA07182A (xx)
PH (1) PH18635A (xx)
PT (1) PT75420B (xx)
ZA (1) ZA825106B (xx)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
CA1259070A (en) * 1983-07-01 1989-09-05 Upjohn Company (The) Substituted 2-¬monoannelated(3,4-,4,5-, and 5,6-)- pyridylalkylenesulfinyl|-benzimidazoles
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
SE8404065D0 (sv) * 1984-08-10 1984-08-10 Haessle Ab Novel biologically active compounds
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
GB8526154D0 (en) * 1985-02-06 1985-11-27 Kotobuki Seiyaku Co Ltd 2-substituted cyclo-heptoimidazoles
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
AR243167A1 (es) * 1985-08-24 1993-07-30 Hoechst Ag Procedimiento para la preparacion de toluidinas sustituidas.
EP0786461A1 (en) * 1986-11-13 1997-07-30 Eisai Co., Ltd. Pyridine derivatives, pharmaceutical compositions comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
JP2718945B2 (ja) * 1987-06-17 1998-02-25 エーザイ株式会社 ピリジン誘導体及びそれを含有する潰瘍治療剤
US5223515A (en) * 1988-08-18 1993-06-29 Takeda Chemical Industries, Ltd. Injectable solution containing a pyridyl methylsulfinylbenzimidazole
AT394368B (de) * 1990-08-07 1992-03-25 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung von 3,4-dialkoxypyridinen
CA2136993A1 (en) * 1992-06-01 1993-12-09 Takeshi Kawakita Pyridine compound and pharmaceutical use thereof
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions
US5387600A (en) * 1992-07-30 1995-02-07 Fuji Photo Film Co., Ltd. Treating arteriosclerosis using benzimidazole compositions
CA2175235A1 (en) * 1993-10-29 1995-05-04 Takeshi Kawakita Pyridine compound and medicinal use thereof
DE69528843T2 (de) * 1994-06-10 2003-09-18 Ni Skij I Farmakologii Akademi Pharmakologisch aktive 2-mercaptobenzimidazolderivate
US7230014B1 (en) 1997-10-14 2007-06-12 Eisai Co., Ltd. Pharmaceutical formulation comprising glycine as a stabilizer
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
DE10140492A1 (de) 2001-08-17 2003-08-14 Gruenenthal Gmbh Hydrate von gegebenenfalls substituierten 2-(2-Pyridinyl)methylthio-1H-benzimidazolen und Verfahren zu ihrer Herstellung
CN102775388B (zh) 2004-09-13 2016-01-20 武田药品工业株式会社 氧化化合物的制备方法和制备装置
WO2007105551A1 (ja) 2006-03-10 2007-09-20 Arigen Pharmaceuticals, Inc. 抗ヘリコバクター・ピロリ作用を有する新規ピリジン誘導体
AU2007317561A1 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
PT2103608E (pt) 2006-12-18 2012-09-24 Arigen Pharmaceuticals Inc Agente de erradicação de helicobacter pylori possuindo uma actividade inibidora na secreção de ácido gástrico
JP2011512416A (ja) 2008-02-20 2011-04-21 ザ・キュレイターズ・オブ・ザ・ユニバーシティー・オブ・ミズーリ オメプラゾール及びランソプラゾールの組合せと緩衝剤を含んでなる組成物とそれを使用する方法
AU2010235726B2 (en) * 2009-04-09 2012-01-19 Link Genomics, Inc. Pyridine thio derivative, and pharmaceutical composition which contains same and has anti-Helicobacter pylori action
US8722026B2 (en) 2010-01-06 2014-05-13 Elc Management, Llc Skin lightening compositions
US8992897B2 (en) * 2010-01-06 2015-03-31 Elc Management Llc Skin lightening compositions
AU2013267022B2 (en) * 2010-01-06 2016-04-21 Elc Management Llc Skin lightening compositions
WO2018053161A1 (en) * 2016-09-14 2018-03-22 National Taiwan University Novel substituted benzimidazole derivatives as d-amino acid oxidase (daao) inhibitors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7112208A (xx) * 1971-09-04 1973-03-06
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (xx) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects

Also Published As

Publication number Publication date
EP0074341A1 (en) 1983-03-16
ZA825106B (en) 1983-04-27
ES8401482A1 (es) 1983-12-16
US4746667A (en) 1988-05-24
DK362482A (da) 1983-02-14
IS1360B6 (is) 1989-05-25
EP0074341B1 (en) 1986-03-26
FI822813A0 (fi) 1982-08-12
NZ201538A (en) 1985-12-13
PT75420B (en) 1986-12-09
HK2189A (en) 1989-01-20
IL66340A0 (en) 1982-11-30
AU556736B2 (en) 1986-11-20
JPH0313203B2 (xx) 1991-02-22
KR880001714B1 (ko) 1988-09-08
PH18635A (en) 1985-08-23
ES8500265A1 (es) 1984-10-01
PT75420A (en) 1982-09-01
CS249124B2 (en) 1987-03-12
ES8502109A1 (es) 1984-12-16
AU8697882A (en) 1983-02-17
KR840001156A (ko) 1984-03-28
HU190408B (en) 1986-09-29
OA07182A (fr) 1984-04-30
DE3270116D1 (en) 1986-04-30
CA1226223A (en) 1987-09-01
NO822686L (no) 1983-02-14
GR76267B (xx) 1984-08-04
FI822813L (fi) 1983-02-14
IE54215B1 (en) 1989-07-19
MY8700139A (en) 1987-12-31
IS2749A7 (is) 1983-02-14
ATE18765T1 (de) 1986-04-15
DD202876A5 (de) 1983-10-05
ES514947A0 (es) 1983-12-16
IE821940L (en) 1983-02-13
CY1450A (en) 1989-03-10
ES532044A0 (es) 1984-12-16
JPS5839622A (ja) 1983-03-08
ES523344A0 (es) 1984-10-01

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