ATE533757T1 - Neues pyridinderivat mit wirkung gegen helicobacter pylori - Google Patents
Neues pyridinderivat mit wirkung gegen helicobacter pyloriInfo
- Publication number
- ATE533757T1 ATE533757T1 AT07715278T AT07715278T ATE533757T1 AT E533757 T1 ATE533757 T1 AT E533757T1 AT 07715278 T AT07715278 T AT 07715278T AT 07715278 T AT07715278 T AT 07715278T AT E533757 T1 ATE533757 T1 AT E533757T1
- Authority
- AT
- Austria
- Prior art keywords
- gastric
- helicobacter pylori
- pyridine derivative
- pyroli
- effect against
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 2
- 229940037467 helicobacter pylori Drugs 0.000 title abstract 2
- 241000590002 Helicobacter pylori Species 0.000 title 1
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical class C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 1
- 208000005718 Stomach Neoplasms Diseases 0.000 abstract 2
- 206010017758 gastric cancer Diseases 0.000 abstract 2
- 201000011549 stomach cancer Diseases 0.000 abstract 2
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 241000589989 Helicobacter Species 0.000 abstract 1
- 208000037062 Polyps Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- 238000012143 endoscopic resection Methods 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 208000017215 gastric mucosa-associated lymphoid tissue lymphoma Diseases 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 208000017819 hyperplastic polyp Diseases 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 150000003222 pyridines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2006066431 | 2006-03-10 | ||
| PCT/JP2007/054387 WO2007105551A1 (ja) | 2006-03-10 | 2007-03-07 | 抗ヘリコバクター・ピロリ作用を有する新規ピリジン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE533757T1 true ATE533757T1 (de) | 2011-12-15 |
Family
ID=38509384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07715278T ATE533757T1 (de) | 2006-03-10 | 2007-03-07 | Neues pyridinderivat mit wirkung gegen helicobacter pylori |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20090143438A1 (de) |
| EP (1) | EP2003130B1 (de) |
| JP (1) | JP5053992B2 (de) |
| KR (1) | KR101348643B1 (de) |
| CN (1) | CN101400670B (de) |
| AT (1) | ATE533757T1 (de) |
| AU (1) | AU2007225935B2 (de) |
| BR (1) | BRPI0708601A2 (de) |
| CA (1) | CA2645467C (de) |
| DK (1) | DK2003130T3 (de) |
| ES (1) | ES2374730T3 (de) |
| MX (1) | MX2008011594A (de) |
| PL (1) | PL2003130T3 (de) |
| PT (1) | PT2003130E (de) |
| RU (1) | RU2433126C2 (de) |
| SI (1) | SI2003130T1 (de) |
| WO (1) | WO2007105551A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102041615B1 (ko) | 2017-09-29 | 2019-11-06 | 서울프로폴리스 주식회사 | 원산지가 다른 프로폴리스 추출물을 혼합 사용하는 프로폴리스의 사용방법 및 프로폴리스를 유효성분으로 하는 건강기능식품용 조성물 |
| KR102001024B1 (ko) | 2017-09-29 | 2019-07-17 | 서울프로폴리스 주식회사 | 프로폴리스를 포함하는, 위염 및 헬리코박터 파일로리 억제를 위한 조성물 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE418966B (sv) * | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
| ZA825106B (en) | 1981-08-13 | 1983-04-27 | Haessle Ab | Novel pharmaceutical compositions |
| ZW4585A1 (en) * | 1984-04-19 | 1985-11-20 | Hoffmann La Roche | Imidazole derivatives |
| JPS6150979A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| JPS6150978A (ja) * | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
| FI90544C (fi) * | 1986-11-13 | 1994-02-25 | Eisai Co Ltd | Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi |
| JPH0674272B2 (ja) * | 1986-11-13 | 1994-09-21 | エーザイ株式会社 | ピリジン誘導体及びそれを含有する潰瘍治療剤 |
| JP2694361B2 (ja) | 1989-02-09 | 1997-12-24 | アストラ アクチエボラグ | 抗菌剤 |
| JPH0720865B2 (ja) * | 1989-02-10 | 1995-03-08 | 武田薬品工業株式会社 | 抗菌剤 |
| ES2066120T3 (es) * | 1989-02-10 | 1995-03-01 | Takeda Chemical Industries Ltd | Uso de derivados de bencimidazol como agentes antibacterianos. |
| JPH0348680A (ja) | 1989-07-18 | 1991-03-01 | Yoshitomi Pharmaceut Ind Ltd | 抗菌剤 |
| JP2798588B2 (ja) | 1992-08-21 | 1998-09-17 | エーザイ株式会社 | 抗菌剤 |
| JPH07126189A (ja) * | 1993-09-09 | 1995-05-16 | Takeda Chem Ind Ltd | 抗潰瘍併用療法用製剤 |
| ATE192932T1 (de) * | 1993-09-09 | 2000-06-15 | Takeda Chemical Industries Ltd | Formulierung enthaltend einen antibakteriellen und einen antiulcus wirkstoff |
| HUT76639A (en) * | 1994-07-20 | 1997-10-28 | Byk Gulden Lomberg Chem Fab | Pyridyl-thio-compounds, process for producing them and their use |
| EP0775692B1 (de) | 1994-08-30 | 2000-12-06 | Teikoku Chemical Industry Co., Ltd. | Guanidylmethyl cyclohexancarbonsäure ester derivate |
| CN1205632A (zh) * | 1995-12-22 | 1999-01-20 | 帝国化学产业株式会社 | 抗幽门螺杆菌剂 |
| ES2301171T3 (es) * | 1995-12-22 | 2008-06-16 | Nagase Chemtex Corporation | Agente anti-helicobacter pylori. |
| ES2171116B1 (es) * | 2000-04-14 | 2003-08-01 | Esteve Quimica Sa | Procedimiento para la obtencion de derivados de (((piridil sustituido)metil)tio)bencimidazol. |
| JP4490765B2 (ja) | 2004-08-24 | 2010-06-30 | 株式会社東芝 | 熱−電気直接変換装置 |
-
2007
- 2007-03-07 AT AT07715278T patent/ATE533757T1/de active
- 2007-03-07 WO PCT/JP2007/054387 patent/WO2007105551A1/ja not_active Ceased
- 2007-03-07 DK DK07715278.3T patent/DK2003130T3/da active
- 2007-03-07 RU RU2008140164/04A patent/RU2433126C2/ru not_active IP Right Cessation
- 2007-03-07 PT PT07715278T patent/PT2003130E/pt unknown
- 2007-03-07 US US12/225,007 patent/US20090143438A1/en not_active Abandoned
- 2007-03-07 AU AU2007225935A patent/AU2007225935B2/en not_active Ceased
- 2007-03-07 MX MX2008011594A patent/MX2008011594A/es active IP Right Grant
- 2007-03-07 PL PL07715278T patent/PL2003130T3/pl unknown
- 2007-03-07 CA CA2645467A patent/CA2645467C/en not_active Expired - Fee Related
- 2007-03-07 ES ES07715278T patent/ES2374730T3/es active Active
- 2007-03-07 JP JP2008505075A patent/JP5053992B2/ja not_active Expired - Fee Related
- 2007-03-07 EP EP07715278A patent/EP2003130B1/de not_active Not-in-force
- 2007-03-07 BR BRPI0708601-6A patent/BRPI0708601A2/pt not_active IP Right Cessation
- 2007-03-07 KR KR1020087020176A patent/KR101348643B1/ko not_active Expired - Fee Related
- 2007-03-07 CN CN2007800086759A patent/CN101400670B/zh not_active Expired - Fee Related
- 2007-03-07 SI SI200730819T patent/SI2003130T1/sl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2003130B1 (de) | 2011-11-16 |
| RU2433126C2 (ru) | 2011-11-10 |
| KR20090005292A (ko) | 2009-01-13 |
| CN101400670B (zh) | 2012-10-10 |
| KR101348643B1 (ko) | 2014-01-08 |
| HK1122290A1 (en) | 2009-05-15 |
| PT2003130E (pt) | 2012-01-10 |
| CA2645467A1 (en) | 2007-09-20 |
| US20090143438A1 (en) | 2009-06-04 |
| RU2008140164A (ru) | 2010-04-20 |
| AU2007225935A1 (en) | 2007-09-20 |
| PL2003130T3 (pl) | 2012-04-30 |
| EP2003130A4 (de) | 2010-12-22 |
| EP2003130A2 (de) | 2008-12-17 |
| SI2003130T1 (sl) | 2012-02-29 |
| DK2003130T3 (da) | 2011-12-12 |
| BRPI0708601A2 (pt) | 2011-06-07 |
| AU2007225935B2 (en) | 2011-12-22 |
| JP5053992B2 (ja) | 2012-10-24 |
| CA2645467C (en) | 2012-04-24 |
| CN101400670A (zh) | 2009-04-01 |
| WO2007105551A1 (ja) | 2007-09-20 |
| MX2008011594A (es) | 2008-09-22 |
| ES2374730T3 (es) | 2012-02-21 |
| EP2003130A9 (de) | 2009-04-15 |
| JPWO2007105551A1 (ja) | 2009-07-30 |
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