ES477420A1 - Procedimiento para la preparacion de derivados de purina. - Google Patents

Procedimiento para la preparacion de derivados de purina.

Info

Publication number
ES477420A1
ES477420A1 ES477420A ES477420A ES477420A1 ES 477420 A1 ES477420 A1 ES 477420A1 ES 477420 A ES477420 A ES 477420A ES 477420 A ES477420 A ES 477420A ES 477420 A1 ES477420 A1 ES 477420A1
Authority
ES
Spain
Prior art keywords
piperidinopropyl
processes
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES477420A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES477420A1 publication Critical patent/ES477420A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedimiento para la preparación de derivados de purina de la fórmula general I **(Fórmula)** en que R1 significa hidrógeno o un grupo alcohilo inferior, R2 significa hidrógeno, un grupo arilo o alcohilo inferior, que eventualmente puede estar substituido con hidroxilo, pudiendo formar R1 y R2 también juntamente con al átomo de nitrógeno un anillo heterocíclico, y R3 significa un grupo acilo o hidrógeno, así como sus sales farmacológicamente inocuas.
ES477420A 1978-02-02 1979-02-02 Procedimiento para la preparacion de derivados de purina. Expired ES477420A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782804416 DE2804416A1 (de) 1978-02-02 1978-02-02 Neue purin-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ES477420A1 true ES477420A1 (es) 1979-07-01

Family

ID=6030974

Family Applications (1)

Application Number Title Priority Date Filing Date
ES477420A Expired ES477420A1 (es) 1978-02-02 1979-02-02 Procedimiento para la preparacion de derivados de purina.

Country Status (16)

Country Link
US (1) US4212866A (es)
EP (1) EP0003558B1 (es)
JP (1) JPS54109999A (es)
AT (1) AT361009B (es)
CA (1) CA1108612A (es)
DD (1) DD141310A5 (es)
DE (2) DE2804416A1 (es)
DK (1) DK143108C (es)
ES (1) ES477420A1 (es)
FI (1) FI790285A (es)
HU (1) HU179934B (es)
IE (1) IE47807B1 (es)
IL (1) IL56531A (es)
PT (1) PT69156A (es)
SU (1) SU858568A3 (es)
ZA (1) ZA79408B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2922159A1 (de) * 1979-05-31 1980-12-04 Boehringer Mannheim Gmbh Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3529497A1 (de) * 1985-08-17 1987-02-26 Boehringer Mannheim Gmbh N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
FR2699176B1 (fr) * 1992-12-11 1995-03-03 Adir Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
FR2741881B1 (fr) * 1995-12-01 1999-07-30 Centre Nat Rech Scient Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
KR20010012316A (ko) 1997-05-08 2001-02-15 스튜어트 알. 수터, 스티븐 베네티아너, 피터 존 기딩스 프로테아제 억제제
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2245061A1 (de) * 1972-09-14 1974-03-28 Boehringer Mannheim Gmbh Derivate des adenins
DE2401254A1 (de) * 1974-01-11 1975-11-27 Boehringer Mannheim Gmbh Neue derivate von n hoch 6-substituierten adeninen
DE2550000A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Neue purin-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ZA79408B (en) 1980-02-27
HU179934B (en) 1983-01-28
DD141310A5 (de) 1980-04-23
CA1108612A (en) 1981-09-08
IL56531A0 (en) 1979-03-12
ATA71379A (de) 1980-07-15
EP0003558A1 (de) 1979-08-22
PT69156A (de) 1979-02-01
DE2804416A1 (de) 1979-08-09
DE2961037D1 (en) 1981-12-24
SU858568A3 (ru) 1981-08-23
JPS54109999A (en) 1979-08-29
AT361009B (de) 1981-02-10
EP0003558B1 (de) 1981-10-21
FI790285A (fi) 1979-08-03
IE47807B1 (en) 1984-06-27
US4212866A (en) 1980-07-15
DK143108B (da) 1981-03-30
IL56531A (en) 1982-05-31
IE790190L (en) 1979-08-02
DK143108C (da) 1981-11-02
DK44379A (da) 1979-08-03

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