ES8101074A1 - Procedimiento para la preparacion de derivados de xantina - Google Patents

Procedimiento para la preparacion de derivados de xantina

Info

Publication number
ES8101074A1
ES8101074A1 ES491915A ES491915A ES8101074A1 ES 8101074 A1 ES8101074 A1 ES 8101074A1 ES 491915 A ES491915 A ES 491915A ES 491915 A ES491915 A ES 491915A ES 8101074 A1 ES8101074 A1 ES 8101074A1
Authority
ES
Spain
Prior art keywords
preparation
compounds
medicaments containing
radical
theophylline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES491915A
Other languages
English (en)
Other versions
ES491915A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES8101074A1 publication Critical patent/ES8101074A1/es
Publication of ES491915A0 publication Critical patent/ES491915A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • C07D473/10—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 3 and 7, e.g. theobromine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE XANTINA. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I), EN QUE UNO DE LOS RADICALES R''1, R''2 SIGNIFICA EL GRUPO METILO, Y EL OTRO, UN ATOMO DE HIDROGENO, CON UN COMPUESTO DE FORMULA X-CH2-CH2-CH2-Y, EN QUE X E Y SIGNIFICAN RADICALES REACTIVOS, *FORMULA* Y CON UN COMPUESTO (II), OBTENIENDOSE EL COMPUESTO DE FORMULA GENERAL (III). LA REACCION SE EFECTUA EN MEDIO ALCALINO, PREFERIBLEMENTE EN UN ALCOHOL INFERIOR TAL COMO EL ISOPROPANOL EN PRESENCIA DE ISOPROPANOLATO SODICO. EFECTO ANTIINFLAMATORIO, ANTIALERGICO, ANTIEDEMATOSO.
ES491915A 1979-05-31 1980-05-28 Procedimiento para la preparacion de derivados de xantina Granted ES491915A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792922159 DE2922159A1 (de) 1979-05-31 1979-05-31 Neue xanthin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8101074A1 true ES8101074A1 (es) 1980-12-16
ES491915A0 ES491915A0 (es) 1980-12-16

Family

ID=6072153

Family Applications (1)

Application Number Title Priority Date Filing Date
ES491915A Granted ES491915A0 (es) 1979-05-31 1980-05-28 Procedimiento para la preparacion de derivados de xantina

Country Status (13)

Country Link
US (1) US4284633A (es)
EP (1) EP0021103B1 (es)
JP (1) JPS55162785A (es)
AT (1) ATE3549T1 (es)
AU (1) AU529812B2 (es)
CA (1) CA1128040A (es)
DD (1) DD151168A5 (es)
DE (2) DE2922159A1 (es)
ES (1) ES491915A0 (es)
HU (1) HU184291B (es)
IL (1) IL60176A (es)
SU (1) SU1079176A3 (es)
ZA (1) ZA803245B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4426383A (en) 1980-09-04 1984-01-17 Eisai Co., Ltd. Theophylline and theobromine derivatives
CH648559A5 (de) * 1981-07-20 1985-03-29 Siegfried Ag Theophyllinderivate und verfahren zu deren herstellung.
FR2558162B1 (fr) * 1984-01-17 1986-04-25 Adir Nouveaux derives de la xanthine, leurs procedes de preparation et les compositions pharmaceutiques les renfermant
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
US7550468B2 (en) * 2000-07-28 2009-06-23 Ing-Jun Chen Theophylline and 3-isobutyl-1 methylxanthine based N-7 substituted derivatives displaying inhibitory activities on PDE-5 phospodiesterase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1133989A (en) * 1964-12-08 1968-11-20 Chugai Pharmaceutical Co Ltd Theophylline derivatives, their salts and process for preparing the same
DE2401254A1 (de) * 1974-01-11 1975-11-27 Boehringer Mannheim Gmbh Neue derivate von n hoch 6-substituierten adeninen
DE2550000A1 (de) * 1975-11-07 1977-05-12 Boehringer Mannheim Gmbh Neue purin-derivate und verfahren zu ihrer herstellung
US4061753A (en) * 1976-02-06 1977-12-06 Interx Research Corporation Treating psoriasis with transient pro-drug forms of xanthine derivatives
DE2804416A1 (de) * 1978-02-02 1979-08-09 Boehringer Mannheim Gmbh Neue purin-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
EP0011399A1 (en) * 1978-11-11 1980-05-28 FISONS plc N-substituted theophyllines, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
DE2922159A1 (de) 1980-12-04
CA1128040A (en) 1982-07-20
EP0021103A1 (de) 1981-01-07
SU1079176A3 (ru) 1984-03-07
US4284633A (en) 1981-08-18
DE3063450D1 (en) 1983-07-07
AU529812B2 (en) 1983-06-23
HU184291B (en) 1984-07-30
JPS55162785A (en) 1980-12-18
ATE3549T1 (de) 1983-06-15
EP0021103B1 (de) 1983-05-25
ZA803245B (en) 1981-06-24
IL60176A0 (en) 1980-07-31
IL60176A (en) 1983-06-15
AU5878780A (en) 1980-12-04
ES491915A0 (es) 1980-12-16
DD151168A5 (de) 1981-10-08

Similar Documents

Publication Publication Date Title
IL73893A (en) 11-aryl-13-estradiene derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE3065304D1 (en) Morpholine derivatives, pharmaceutical compositions containing them and processes for their preparation
ES481873A1 (es) Procedimiento para la preparacion de 2-(2-alcoxietil)-2'- hidroxi-6,7-benzomorfanos.
ES487677A1 (es) Procedimiento para la preparacion de derivados de aril-ete- res
ES482472A1 (es) Procedimiento para la preparacion de isoquinoleinas.
AU7216187A (en) 1,4-disubstituted piperazine derivatives, pharmaceutical compositions containing them and process for preparing same
IL96618A0 (en) Pharmaceutical compositions containing fluoroquinolone derivatives
ES8101074A1 (es) Procedimiento para la preparacion de derivados de xantina
ES480111A1 (es) Procedimiento para la preparacion de nuevos derivados de 2- iminoimidazolidina.
ES8203867A1 (es) Procedimiento para la obtencion de derivados de benzotiazol
ES472085A1 (es) Un procedimiento para la preparacion de una composicion te- rapeutica para el tratamiento de enfermedades alergicas.
ES474367A1 (es) Procedimiento de preparacion de nuevos derivados del benzo- (d)tiazol.
ES458481A1 (es) Un procedimiento de preparacion de nuevos derivados de ben- zodiazepina.
ES8201140A1 (es) Procedimiento para la preparacion de 2-fenilamino-imidazoli nas-(2)sustituidas.
ES487631A1 (es) Procedimiento para la obtencion de hexahidro-1,4-oxazepinas
ES2001893A6 (es) Procedimiento para la obtencion de derivados de metilendioxifenantreno
ES8608509A1 (es) Procedimiento para preparar nuevos derivador de 2-(1-imidazolil)-etanol
ES8102720A1 (es) Procedimiento para la preparacion de 12-deshidrodigoxinoxi- mas
ES481416A1 (es) Un procedimiento para la preparacion de un derivado monoami-da de acido tereftalico.
DE3262706D1 (en) Oximes of 3"'-dehydro-cardenolide-tridigitoxosides, process for their preparation and their use as medicaments