ATE57701T1 - Pyridoindolderivate, ihre verwendung als arzneimittel und diese enthaltende zubereitungen. - Google Patents
Pyridoindolderivate, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.Info
- Publication number
- ATE57701T1 ATE57701T1 AT87400593T AT87400593T ATE57701T1 AT E57701 T1 ATE57701 T1 AT E57701T1 AT 87400593 T AT87400593 T AT 87400593T AT 87400593 T AT87400593 T AT 87400593T AT E57701 T1 ATE57701 T1 AT E57701T1
- Authority
- AT
- Austria
- Prior art keywords
- represents hydrogen
- group
- derivatives
- lower alkyl
- pyridoindol
- Prior art date
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- IVCGJOSPVGENCT-UHFFFAOYSA-N 1h-pyrrolo[2,3-f]quinoline Chemical class N1=CC=CC2=C(NC=C3)C3=CC=C21 IVCGJOSPVGENCT-UHFFFAOYSA-N 0.000 title 1
- 229940126601 medicinal product Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- RDMFHRSPDKWERA-UHFFFAOYSA-N 5H-Pyrido[4,3-b]indole Chemical class C1=NC=C2C3=CC=CC=C3NC2=C1 RDMFHRSPDKWERA-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8604202A FR2595701B1 (fr) | 1986-03-17 | 1986-03-17 | Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant |
| EP87400593A EP0239476B1 (de) | 1986-03-17 | 1987-03-17 | Pyridoindolderivate, ihre Verwendung als Arzneimittel und diese enthaltende Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE57701T1 true ATE57701T1 (de) | 1990-11-15 |
Family
ID=9333475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87400593T ATE57701T1 (de) | 1986-03-17 | 1987-03-17 | Pyridoindolderivate, ihre verwendung als arzneimittel und diese enthaltende zubereitungen. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4835160A (de) |
| EP (1) | EP0239476B1 (de) |
| AT (1) | ATE57701T1 (de) |
| DE (1) | DE3765670D1 (de) |
| ES (1) | ES2026555T3 (de) |
| FR (1) | FR2595701B1 (de) |
| GR (1) | GR3001366T3 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL94600A0 (en) * | 1989-06-06 | 1991-04-15 | Rhone Poulenc Sante | Pyridobenzoindole compounds,their preparation and compositions containing them |
| FR2661411B1 (fr) * | 1990-04-25 | 1992-06-19 | Centre Nat Rech Scient | Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent. |
| FR2647788B1 (fr) * | 1989-06-06 | 1991-09-06 | Centre Nat Rech Scient | Nouveaux derives de pyridobenzoindole, leur preparation et les compositions qui les contiennent |
| FR2823975B1 (fr) * | 2001-04-27 | 2003-05-30 | Sanofi Synthelabo | Nouvelle utilisation de pyridoindolone |
| AU2003272175A1 (en) * | 2002-10-21 | 2004-05-04 | Aprea Ab | Reactivation of wild type p53 in human tumour cells by a low molecular weight compound |
| US7456193B2 (en) * | 2002-10-23 | 2008-11-25 | Sanofi-Aventis | Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics |
| FR2846329B1 (fr) * | 2002-10-23 | 2004-12-03 | Sanofi Synthelabo | Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique |
| FR2869316B1 (fr) * | 2004-04-21 | 2006-06-02 | Sanofi Synthelabo | Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique. |
| FR2892416B1 (fr) * | 2005-10-20 | 2008-06-27 | Sanofi Aventis Sa | Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique |
| EP2280011A1 (de) * | 2009-07-28 | 2011-02-02 | Commissariat à l'Énergie Atomique et aux Énergies Alternatives | Kondensierte Pyridin-Derivate verwendbar als potente Proteinkinase-CK2-Hemmer |
| WO2015161373A1 (en) | 2014-04-22 | 2015-10-29 | Université de Montréal | Compounds and use thereof in the expansion of hematopoietic stem cells and/or hematopoietic progenitor cells |
| EP3262045A1 (de) * | 2015-02-27 | 2018-01-03 | The Regents of The University of Michigan | 9h-pyrimido[4,5-b]indole als bet-bromdomänen-hemmer |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2327783A1 (fr) * | 1975-10-16 | 1977-05-13 | Cm Ind | Application therapeutique de derives d'indolo(3,2-c)quinoleine |
| FR2422662A2 (fr) * | 1978-04-10 | 1979-11-09 | Anvar | Dipyrido (4,3-b) (3,4-f) indoles, procede d'obtention, application therapeutique et compositions pharmaceutiques les contenant |
| FR2579208B1 (fr) * | 1985-03-22 | 1987-05-07 | Sanofi Sa | Nouveaux derives de le 5-h pyrido (3', 4' : 4,5) pyrrolo (3,2-c) pyridine, leur procede de preparation et leur activite antitumorale |
-
1986
- 1986-03-17 FR FR8604202A patent/FR2595701B1/fr not_active Expired
-
1987
- 1987-03-17 DE DE8787400593T patent/DE3765670D1/de not_active Expired - Lifetime
- 1987-03-17 US US07/042,896 patent/US4835160A/en not_active Expired - Fee Related
- 1987-03-17 ES ES198787400593T patent/ES2026555T3/es not_active Expired - Lifetime
- 1987-03-17 AT AT87400593T patent/ATE57701T1/de not_active IP Right Cessation
- 1987-03-17 EP EP87400593A patent/EP0239476B1/de not_active Expired - Lifetime
-
1991
- 1991-01-24 GR GR91400067T patent/GR3001366T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3765670D1 (de) | 1990-11-29 |
| FR2595701A1 (fr) | 1987-09-18 |
| EP0239476A1 (de) | 1987-09-30 |
| US4835160A (en) | 1989-05-30 |
| EP0239476B1 (de) | 1990-10-24 |
| FR2595701B1 (fr) | 1988-07-01 |
| GR3001366T3 (en) | 1992-09-11 |
| ES2026555T3 (es) | 1992-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |