ES449740A1 - Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil) piperidina. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil) piperidina.Info
- Publication number
- ES449740A1 ES449740A1 ES449740A ES449740A ES449740A1 ES 449740 A1 ES449740 A1 ES 449740A1 ES 449740 A ES449740 A ES 449740A ES 449740 A ES449740 A ES 449740A ES 449740 A1 ES449740 A1 ES 449740A1
- Authority
- ES
- Spain
- Prior art keywords
- benzazolylalkyl
- formula
- piperidine derivatives
- salts
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003053 piperidines Chemical class 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 238000007126 N-alkylation reaction Methods 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Otolaryngology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hospice & Palliative Care (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US59779375A | 1975-07-21 | 1975-07-21 | |
| US05/687,139 US4066772A (en) | 1975-07-21 | 1976-05-17 | 1,3-Dihydro-1-[3-(1-piperidinyl)propyl]-2H-benzimidazol-2-ones and related compounds |
| KR7601697A KR810000334B1 (ko) | 1975-07-21 | 1976-07-12 | 1-(벤즈 아조릴알킬) 피페리딘 유도체의 제조방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES449740A1 true ES449740A1 (es) | 1978-02-16 |
Family
ID=27348142
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES449740A Expired ES449740A1 (es) | 1975-07-21 | 1976-07-09 | Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil) piperidina. |
| ES461631A Expired ES461631A1 (es) | 1975-07-21 | 1977-08-16 | Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil)piperidina. |
| ES461630A Expired ES461630A1 (es) | 1975-07-21 | 1977-08-16 | Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil)piperidina. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES461631A Expired ES461631A1 (es) | 1975-07-21 | 1977-08-16 | Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil)piperidina. |
| ES461630A Expired ES461630A1 (es) | 1975-07-21 | 1977-08-16 | Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil)piperidina. |
Country Status (25)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4501749A (en) * | 1983-10-31 | 1985-02-26 | Merck & Co., Inc. | Peripherally selective dopamine antagonists in the treatment of ocular hypertension |
| JPS6248684A (ja) * | 1985-08-26 | 1987-03-03 | Sumitomo Chem Co Ltd | 新規なヨ−ドブチロフエノン誘導体およびその製造法 |
| JPS62251313A (ja) * | 1986-04-25 | 1987-11-02 | 信越ポリマー株式会社 | 結束装置 |
| FR2723091B1 (fr) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | Tetrahydropyridine-(6,4-hydroxypiperidine) alkylazoles |
| US6355659B1 (en) | 1994-07-29 | 2002-03-12 | Laboratorios Del Dr. Esteve, S.A. | 4-(4-Chlorophenyl)-1236-tetrahydro-1(1H-124-triazol-1-yl)butty)pyrideine and salts thereof; pharmaceutical compositions and method of treating psychoses utilizing same |
| RU2192848C1 (ru) * | 2001-10-30 | 2002-11-20 | Закрытое акционерное общество "ВЕРОФАРМ" | Противорвотное средство |
| PA8603801A1 (es) * | 2003-05-27 | 2004-12-16 | Janssen Pharmaceutica Nv | Derivados de la quinazolina |
| RU2268047C2 (ru) * | 2003-12-15 | 2006-01-20 | Закрытое акционерное общество "Фармацевтическое предприятие "Оболенское" | Лекарственная форма, обладающая противорвотным действием, и способ ее изготовления |
| DE602004012891T2 (de) | 2003-12-18 | 2009-04-09 | Janssen Pharmaceutica N.V. | Pyrido- und pyrimidopyrimidinderivate als anti-proliferative mittel |
| NI200700147A (es) | 2004-12-08 | 2019-05-10 | Janssen Pharmaceutica Nv | Derivados de quinazolina inhibidores de cinasas dirigidos a multip |
| EA014779B1 (ru) | 2006-07-13 | 2011-02-28 | Янссен Фармацевтика Н.В. | Производные хиназолина в качестве mtki |
| EP1997805A1 (en) * | 2007-06-01 | 2008-12-03 | Commissariat à l'Energie Atomique | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans |
| WO2009016132A1 (en) | 2007-07-27 | 2009-02-05 | Janssen Pharmaceutica Nv | Pyrrolopyrimidines |
| KR20140139125A (ko) | 2007-08-31 | 2014-12-04 | 퍼듀 퍼머 엘피 | 치환-퀴녹살린-형 피페리딘 화합물 및 그의 용도 |
| US9090618B2 (en) | 2012-12-27 | 2015-07-28 | Purdue Pharma L.P. | Substituted benzimidazole-type piperidine compounds and uses thereof |
| AU2017213852B2 (en) * | 2016-02-04 | 2021-04-08 | Cindome Pharma, Inc. | Deuterated domperidone compositions and methods for therapy of disorders |
| KR20240125702A (ko) | 2017-06-30 | 2024-08-19 | 신돔 파마, 인크. | 중수소화 돔페리돈 조성물, 방법, 및 제조 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE633495A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1962-06-13 | |||
| BE633914A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1962-06-22 | |||
| US3629267A (en) * | 1968-10-28 | 1971-12-21 | Smith Kline French Lab | Benzoheterocyclicalkyl derivatives of 4-(2-keto -1-benzimidazolinyl)-piperidine 4-(2-keto - 1 - benzimidazolinyl) -1 2 3 6 tetrahydropyridine 1 - phenyl - 1 3 8-triazaspiro(4 5)decan - 4 - one and 2 4 9-triazaspiro(5 5)undecan-1 3 5-trione |
| AU4698672A (en) * | 1972-09-22 | 1972-11-09 | Ciba-Geigy Ag | Azacycloaliphatic compounds, process for their manufacture and compositions containing them |
| FR2218100A1 (en) * | 1973-02-20 | 1974-09-13 | Janssen Pharmaceutica Nv | Neuroleptic tricyclic derivs. - of benzimidazolinones and triazaspiro-4,5-decan-4-ones |
| US3989707A (en) * | 1974-06-21 | 1976-11-02 | Janssen Pharmaceutica N.V. | Benzimidazolinone derivatives |
-
1976
- 1976-06-23 NZ NZ181256A patent/NZ181256A/xx unknown
- 1976-06-30 GB GB7627242A patent/GB1542514A/en not_active Expired
- 1976-07-07 CA CA256,450A patent/CA1085852A/en not_active Expired
- 1976-07-07 RO RO7686860A patent/RO70566A/ro unknown
- 1976-07-08 PH PH18663A patent/PH13710A/en unknown
- 1976-07-09 ES ES449740A patent/ES449740A1/es not_active Expired
- 1976-07-09 LU LU75354A patent/LU75354A1/xx unknown
- 1976-07-16 CS CS764688A patent/CS202550B2/cs unknown
- 1976-07-16 AU AU15964/76A patent/AU511027B2/en not_active Expired
- 1976-07-19 IT IT50499/76A patent/IT1062614B/it active
- 1976-07-19 JP JP51085216A patent/JPS5217475A/ja active Granted
- 1976-07-20 DK DK327576A patent/DK154950C/da not_active IP Right Cessation
- 1976-07-20 SE SE7608265A patent/SE426490B/xx not_active IP Right Cessation
- 1976-07-20 CH CH929176A patent/CH623820A5/de not_active IP Right Cessation
- 1976-07-20 BG BG033791A patent/BG26526A3/xx unknown
- 1976-07-20 PT PT65387A patent/PT65387B/pt unknown
- 1976-07-20 NL NLAANVRAGE7608023,A patent/NL187442C/xx not_active IP Right Cessation
- 1976-07-20 IE IE1602/76A patent/IE43496B1/en not_active IP Right Cessation
- 1976-07-20 AT AT0534776A patent/AT364358B/de not_active IP Right Cessation
- 1976-07-20 FI FI762086A patent/FI62667C/fi not_active IP Right Cessation
- 1976-07-21 YU YU1794/76A patent/YU39969B/xx unknown
- 1976-07-21 DE DE19762632870 patent/DE2632870A1/de active Granted
-
1977
- 1977-08-16 ES ES461631A patent/ES461631A1/es not_active Expired
- 1977-08-16 ES ES461630A patent/ES461630A1/es not_active Expired
-
1980
- 1980-03-20 HK HK141/80A patent/HK14180A/xx unknown
- 1980-12-11 SE SE8008713A patent/SE435621B/sv not_active IP Right Cessation
-
1981
- 1981-12-30 MY MY17/81A patent/MY8100017A/xx unknown
-
1982
- 1982-05-21 KE KE3215A patent/KE3215A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES449740A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 1-(benzazolilalquil) piperidina. | |
| IE41383B1 (en) | 1-(1-(4,4-diphenylbutyl)-piperidin-4-yl)-1,3-dihydro-2h-benzimidazol-2-ones | |
| ES8406193A1 (es) | Procedimiento para la preparacion de nuevas 1,4-dihidropiridinas sustituidas | |
| BG41822A3 (en) | Method for preparing pyridyl derivatives | |
| ES8604543A1 (es) | Procedimiento para la obtencion de derivados piperazinicos | |
| SE7604476L (sv) | Forfarande for framstellning av 1-(3,3,3-triarylpropyl)-4-fenyl-4-piperidinmetanolforeningar | |
| ES451768A1 (es) | Un procedimiento para la preparacion de un compuesto quimicoseleccionado entre el grupo formado por una n-aril-n(4-pipe-ridinil) aril-acetamida. | |
| SE7612964L (sv) | Tienamycinderivat | |
| ES482138A1 (es) | Procedimiento para la obtencion de 1-bencil -fenil-piperidi-nas. | |
| ES8501607A1 (es) | Procedimiento para la obtencion de heterociclos nitrogenosos de 5 miembros | |
| ES417471A1 (es) | Procedimiento para la preparacion de derivados de n(6)-a- ralcohil-adenosina acilados. | |
| ES301365A1 (es) | Un método para la preparación de un compuesto diurético | |
| IL66384A (en) | Indolin-2-one(3,4-dihydroquinol-2-one or quinol-2-one)-oxyalkylsulphimines and salts thereof,their preparation and pharmaceutical compositions containing them | |
| JPS51125389A (en) | A process for preparing heterocyclic compovnds | |
| SE436870B (sv) | Sett att framstella nya n-substituerade kanelsyraamider | |
| ES439180A1 (es) | Procedimiento para la preparacion de derivados de piperido- na. | |
| GB1498200A (en) | Herbicidally effective 1,3,4-thiadiazolyl-(2)-hexahydrotriazinone derivatives | |
| SE7706693L (sv) | Sett att framstella hydrazinopyridazinderivat | |
| GB1420758A (en) | Anti-ulcer compositions | |
| GB1102357A (en) | Piperidine derivatives and process for their production | |
| GB1074744A (en) | Improvements in or relating to substituted 9,10-dihydro-4h-benzo[4,5]cyclo-hepta[1,2-b]thiophenes | |
| ES443720A1 (es) | Un procedimiento para la produccion de derivados de acidos 20-alcoxi-16-alquilprostadienoicos. | |
| ES397912A1 (es) | Procedimiento para la obtencion de derivados de piperidina. | |
| ES327879A1 (es) | Un procedimiento para la obtencion de nuevas i-cicloalcohiledenetil-4-fenil-piperidinas. | |
| GR34663B (el) | Μεθοδος δια την παρασκευην παραγωγων φενυλαμινοεθανολης. |