ES401614A1 - Procedimiento para la obtencion de 1,4-dihidro - piridin- carboxilatos asimetricos. - Google Patents

Procedimiento para la obtencion de 1,4-dihidro - piridin- carboxilatos asimetricos.

Info

Publication number
ES401614A1
ES401614A1 ES401614A ES401614A ES401614A1 ES 401614 A1 ES401614 A1 ES 401614A1 ES 401614 A ES401614 A ES 401614A ES 401614 A ES401614 A ES 401614A ES 401614 A1 ES401614 A1 ES 401614A1
Authority
ES
Spain
Prior art keywords
formula
alkyl
substituted
indicated above
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES401614A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=5804433&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES401614(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES401614A1 publication Critical patent/ES401614A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Coloring (AREA)
ES401614A 1971-04-10 1972-04-08 Procedimiento para la obtencion de 1,4-dihidro - piridin- carboxilatos asimetricos. Expired ES401614A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2117571A DE2117571C3 (de) 1971-04-10 1971-04-10 Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel

Publications (1)

Publication Number Publication Date
ES401614A1 true ES401614A1 (es) 1975-11-01

Family

ID=5804433

Family Applications (1)

Application Number Title Priority Date Filing Date
ES401614A Expired ES401614A1 (es) 1971-04-10 1972-04-08 Procedimiento para la obtencion de 1,4-dihidro - piridin- carboxilatos asimetricos.

Country Status (28)

Country Link
US (1) US3799934A (h)
JP (1) JPS5529989B1 (h)
AT (1) AT316551B (h)
AU (1) AU464663B2 (h)
BE (1) BE781878A (h)
BG (1) BG22818A3 (h)
CA (1) CA921035A (h)
CH (1) CH567472A5 (h)
CS (1) CS175429B2 (h)
DD (2) DD99371A5 (h)
DE (1) DE2117571C3 (h)
DK (1) DK132496C (h)
ES (1) ES401614A1 (h)
FI (1) FI55186C (h)
FR (1) FR2132830B1 (h)
GB (1) GB1358951A (h)
HK (1) HK18877A (h)
HU (1) HU164705B (h)
IE (1) IE36265B1 (h)
IL (1) IL39171A (h)
LU (1) LU65138A1 (h)
NL (1) NL164031C (h)
NO (1) NO135589C (h)
PL (1) PL84499B1 (h)
RO (2) RO62643A (h)
SE (1) SE371823B (h)
SU (1) SU435612A3 (h)
ZA (1) ZA722348B (h)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2210674C3 (de) * 1972-03-06 1981-09-24 Bayer Ag, 5090 Leverkusen 2-Amino-6-methyl-1,4-dihydropyridine, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
US4001258A (en) * 1972-03-06 1977-01-04 Bayer Aktiengesellschaft 2-amino-1,4-dihydropyridine derivatives
US3917619A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-4,5-dihydropyridine derivatives
US3919246A (en) * 1972-03-06 1975-11-11 Bayer Ag Process for preparing 2-amino-1,4-dihydropyridine derivates
DD106832A5 (h) * 1972-03-06 1974-07-05
US3917622A (en) * 1972-03-06 1975-11-04 Bayer Ag 2-Amino-1,4-dihydropyridine derivatives
US3935223A (en) * 1972-03-06 1976-01-27 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
DE2218644C3 (de) * 1972-04-18 1982-08-19 Bayer Ag, 5090 Leverkusen Basische Ester von 1,4-Dihydropyridinen, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2242786A1 (de) * 1972-08-31 1974-03-14 Bayer Ag Verfahren zur herstellung von neuen 2-amino-1,4-dihydropyridinen mit einer carbonylfunktion sowie ihre verwendung als arzneimittel
US3989708A (en) * 1972-08-31 1976-11-02 Bayer Aktiengesellschaft 2-Amino-1,4-dihydropyridine derivatives
DE2248150A1 (de) * 1972-09-30 1974-04-04 Bayer Ag Dihydropyridinpolyester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
CH607848A5 (h) * 1974-06-04 1978-11-30 Bayer Ag
DE2508181A1 (de) * 1975-02-26 1976-09-09 Bayer Ag 1,4-dihydropyridincarbonsaeurearal- kylester, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE2549568C3 (de) * 1975-11-05 1981-10-29 Bayer Ag, 5090 Leverkusen 2,6-Dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsäureisobutylester, mehrere Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
US4154839A (en) * 1975-11-05 1979-05-15 Bayer Aktiengesellschaft 2,6-Dimethyl-3-carboxymethoxy-4-(2-nitrophenyl)-5-carbisobutoxy-1,4-dihydropyridine
DE2650013C3 (de) * 1976-10-30 1981-04-02 Bayer Ag, 5090 Leverkusen 1.4-Dihydro-2.6-dimethyl-4-(3-nitrophenyl)-3.5-pyridindicarbonsäureisopropyl-(2-propoxy-äthyl)-ester, Verfahren zu seiner Herstellung sowie ihn enthaltende Arzneimittel
DE2658183A1 (de) * 1976-12-22 1978-07-06 Bayer Ag In 2-position substituierte 1,4- dihydropyridin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
JPS55301A (en) * 1978-02-14 1980-01-05 Yamanouchi Pharmaceut Co Ltd 1,4-dihydropyridine-3,5-dicarboxylic ester derivative and its preparation
DE2815578C2 (de) * 1978-04-11 1986-01-16 Bayer Ag, 5090 Leverkusen Neue pharmazeutische Verwendung von Nimodipin
SE429652B (sv) * 1978-06-30 1983-09-19 Haessle Ab 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester
DE2837477A1 (de) * 1978-08-28 1980-03-13 Bayer Ag Sila-substituierte 1,4-dihydropyridin- derivate
DE2841667A1 (de) * 1978-09-25 1980-04-10 Bayer Ag Fluorhaltige 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2949464A1 (de) * 1978-12-18 1980-06-26 Sandoz Ag Benzoxadiazole und benzothiadiazole, ihre herstellung und verwendung
DE2927933A1 (de) * 1979-07-11 1981-02-05 Hoechst Ag Acetylacetoxyalkyl-allyl-ether, ihre herstellung und verwendung
DE2935451A1 (de) * 1979-09-01 1981-03-19 Bayer Ag, 5090 Leverkusen Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel
DE3023820A1 (de) * 1980-06-25 1982-01-14 Bayer Ag, 5090 Leverkusen 4,4-disubstituierte spiro-1,4-dihydropyridine, ein verfahren zu ihrer herstellung, sowie ihre verwendung als zwischenprodukt
DE3042769A1 (de) * 1980-11-13 1982-06-09 Bayer Ag, 5090 Leverkusen C-3 verknuepfte 1,4-dihydropyridine, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
US4321384A (en) * 1981-02-27 1982-03-23 American Home Products Corporation Antihypertensive agents
US4365063A (en) * 1981-08-31 1982-12-21 American Home Products Corporation Antihypertensive agents
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3130041A1 (de) * 1981-07-30 1983-02-17 Bayer Ag, 5090 Leverkusen Dihydropyridine mit positiv inotroper wirkung, neue verbindungen, ihre verwendung in arzneimitteln und verfahren zu ihrer herstellung
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JPS58159490A (ja) * 1982-02-23 1983-09-21 Nikken Kagaku Kk １，４−ジヒドロピリジン化合物
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3212736A1 (de) * 1982-04-06 1983-10-13 Bayer Ag, 5090 Leverkusen Verwendung von dihydropyridinen in arzneimitteln mit salidiuretischer wirkung
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
US4656181A (en) * 1982-11-24 1987-04-07 Cermol S.A. Esters of 1,4-dihydropyridines, processes for the preparation of the new esters, and medicaments containing the same
DE3248548A1 (de) * 1982-12-29 1984-07-05 Heinrich Mack Nachf., 7918 Illertissen Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3316510A1 (de) * 1983-05-06 1984-11-08 Bayer Ag Parenterale formulierung von nimodipin, ein verfahren zu ihrer herstellung sowie ihre verwendung bei der bekaempfung von erkrankungen
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US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
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US4757071A (en) * 1984-12-14 1988-07-12 Nisshin Flour Milling Co., Ltd. 1,4-dihydropyridine derivatives, and pharmaceutical compositions containing same, useful for treating cardiovascular diseases
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
US4771057A (en) * 1986-02-03 1988-09-13 University Of Alberta Reduced pyridyl derivatives with cardiovascular regulating properties
US4758669A (en) * 1986-05-05 1988-07-19 Radiation Oncology Center Research And Development Corporation 4-(nitrone aryl) dihydropyridines
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US2359329A (en) * 1943-06-18 1944-10-03 Burroughs Wellcome Co Quinoline substituted dihydropyridines
DE1923990C3 (de) * 1969-05-10 1978-11-23 Bayer Ag Verfahren zur Herstellung von N-substituierten M-Dihydropyridin-S.S-dicarbonsäureestern

Also Published As

Publication number Publication date
GB1358951A (en) 1974-07-03
ZA722348B (en) 1972-12-27
IE36265B1 (en) 1976-09-29
US3799934A (en) 1974-03-26
CA921035A (en) 1973-02-13
DE2117571B2 (de) 1979-01-11
NL164031C (nl) 1980-11-17
HU164705B (h) 1974-04-11
FR2132830A1 (h) 1972-11-24
IE36265L (en) 1972-10-10
RO62643A (fr) 1978-05-15
AT316551B (de) 1974-07-25
NO135589B (h) 1977-01-17
DD102077A5 (h) 1973-12-05
FI55186C (fi) 1979-06-11
CS175429B2 (h) 1977-05-31
PL84499B1 (h) 1976-04-30
AU4045572A (en) 1973-10-04
JPS5529989B1 (h) 1980-08-07
DD99371A5 (h) 1973-08-05
DE2117571A1 (de) 1972-10-19
DK132496B (da) 1975-12-15
IL39171A0 (en) 1972-07-26
BG22818A3 (bg) 1977-04-20
FR2132830B1 (h) 1975-12-26
FI55186B (fi) 1979-02-28
AU464663B2 (en) 1975-08-18
RO60479A (h) 1976-08-15
SE371823B (h) 1974-12-02
DE2117571C3 (de) 1979-10-11
NL7204693A (h) 1972-10-12
HK18877A (en) 1977-04-29
NL164031B (nl) 1980-06-16
BE781878A (fr) 1972-10-10
IL39171A (en) 1975-04-25
LU65138A1 (h) 1972-07-12
SU435612A3 (ru) 1974-07-05
DK132496C (da) 1976-05-24
CH567472A5 (h) 1975-10-15
NO135589C (h) 1977-04-27

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