ES2884044T3 - Profármaco alquilante de fosforamidato para el tratamiento del cáncer - Google Patents
Profármaco alquilante de fosforamidato para el tratamiento del cáncer Download PDFInfo
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- ES2884044T3 ES2884044T3 ES07869800T ES07869800T ES2884044T3 ES 2884044 T3 ES2884044 T3 ES 2884044T3 ES 07869800 T ES07869800 T ES 07869800T ES 07869800 T ES07869800 T ES 07869800T ES 2884044 T3 ES2884044 T3 ES 2884044T3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87186506P | 2006-12-26 | 2006-12-26 | |
| PCT/US2007/088645 WO2008083101A1 (en) | 2006-12-26 | 2007-12-21 | Phosphoramidate alkylator prodrugs for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2884044T3 true ES2884044T3 (es) | 2021-12-10 |
Family
ID=39588979
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07869800T Active ES2884044T3 (es) | 2006-12-26 | 2007-12-21 | Profármaco alquilante de fosforamidato para el tratamiento del cáncer |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8552048B2 (OSRAM) |
| EP (1) | EP2114157B1 (OSRAM) |
| JP (1) | JP5357049B2 (OSRAM) |
| ES (1) | ES2884044T3 (OSRAM) |
| WO (1) | WO2008083101A1 (OSRAM) |
Families Citing this family (37)
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| ZA200507752B (en) | 2003-03-28 | 2007-01-31 | Threshold Pharmaceuticals Inc | Compositions and methods for treating cancer |
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| ES2884044T3 (es) | 2006-12-26 | 2021-12-10 | Immunogenesis Inc | Profármaco alquilante de fosforamidato para el tratamiento del cáncer |
| JP5765634B2 (ja) * | 2008-10-21 | 2015-08-19 | スレッシュホールド ファーマシューティカルズ， インコーポレイテッド | 低酸素活性化型プロドラッグを用いるがんの処置 |
| WO2012006032A2 (en) * | 2010-06-28 | 2012-01-12 | Threshold Pharmaceuticals, Inc. | Treatment of blood cancer |
| RU2597844C2 (ru) | 2010-07-12 | 2016-09-20 | Тресхолд Фармасьютикалз, Инк. | Введение гипоксически активируемых пролекарств и средств, препятствующих ангиогенезу, для лечения рака |
| WO2012135757A2 (en) * | 2011-04-01 | 2012-10-04 | Threshold Pharmaceuticals, Inc. | Methods for treating cancer |
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| JP5922791B2 (ja) | 2012-10-29 | 2016-05-24 | 京セラ株式会社 | 弾性表面波センサ |
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| WO2019238886A1 (en) | 2018-06-13 | 2019-12-19 | University Of Dundee | Bifunctional molecules for targeting usp14 |
| KR20210064252A (ko) * | 2018-09-24 | 2021-06-02 | 시에라 온코로지, 인코퍼레이티드 | Cdc7 억제제를 포함하는 암의 치료 방법 |
| EP3650046A1 (en) | 2018-11-08 | 2020-05-13 | Cellis AG | Mesenchymal stem cell based targeted active ingredient delivery system |
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| WO2021185986A1 (en) | 2020-03-18 | 2021-09-23 | Cellis Ag | Ferritin variants with increased stability, complexation ability and transferrin receptor affinity |
| JP7762796B2 (ja) * | 2021-08-27 | 2025-10-30 | アセンタウィッツ ファーマシューティカルズ リミテッド | Ｐａｒｐ阻害剤に耐性のある患者のｔｈ－３０２による治療 |
| JP2024531479A (ja) * | 2021-08-27 | 2024-08-29 | アセンタウィッツ ファーマシューティカルズ リミテッド | 凍結乾燥製剤溶液および凍結乾燥製剤、ならびにそれらの方法および使用 |
| US20250186468A1 (en) | 2022-03-15 | 2025-06-12 | Ascentawits Pharmaceuticals, Ltd. | Method for treating patient with brca-mutated cancer |
| EP4509127A1 (en) | 2022-04-15 | 2025-02-19 | Ascentawits Pharmaceuticals, Ltd. | Method for treating cancer by using th-302 alone or in combination with parp inhibitor |
| EP4529926A1 (en) | 2022-05-23 | 2025-04-02 | Ascentawits Pharmaceuticals, Ltd. | Method for treating cancer by combining alkylating agent prodrug and cell cycle inhibitor |
| CN119907692A (zh) | 2022-09-13 | 2025-04-29 | 塞尔丽思股份公司 | 用于治疗胶质瘤的分离的靶向递送系统 |
| CN119894521A (zh) | 2022-09-22 | 2025-04-25 | 深圳艾欣达伟医药科技有限公司 | 乏氧激活的化合物在制备治疗癌症患者的药物中的用途 |
| EP4637829A1 (en) | 2022-12-20 | 2025-10-29 | Cellis Sp. z o.o. ([Ltd.] | Isolated targeted delivery system for the treatment of ovarian cancer |
| TW202434258A (zh) * | 2023-02-27 | 2024-09-01 | 大陸商深圳艾欣達偉醫藥科技有限公司 | 溶液、凍乾製劑、凍乾製劑單位包裝、注射液及注射液配製方法 |
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| ES2884044T3 (es) | 2006-12-26 | 2021-12-10 | Immunogenesis Inc | Profármaco alquilante de fosforamidato para el tratamiento del cáncer |
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2007
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- 2007-12-21 WO PCT/US2007/088645 patent/WO2008083101A1/en not_active Ceased
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- 2007-12-21 EP EP07869800.8A patent/EP2114157B1/en active Active
- 2007-12-21 US US12/521,290 patent/US8552048B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2114157B1 (en) | 2021-05-26 |
| US8552048B2 (en) | 2013-10-08 |
| US20100183742A1 (en) | 2010-07-22 |
| JP5357049B2 (ja) | 2013-12-04 |
| WO2008083101A1 (en) | 2008-07-10 |
| EP2114157A4 (en) | 2013-01-23 |
| EP2114157A1 (en) | 2009-11-11 |
| JP2010514787A (ja) | 2010-05-06 |
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