ES2884044T3 - Profármaco alquilante de fosforamidato para el tratamiento del cáncer - Google Patents
Profármaco alquilante de fosforamidato para el tratamiento del cáncer Download PDFInfo
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- ES2884044T3 ES2884044T3 ES07869800T ES07869800T ES2884044T3 ES 2884044 T3 ES2884044 T3 ES 2884044T3 ES 07869800 T ES07869800 T ES 07869800T ES 07869800 T ES07869800 T ES 07869800T ES 2884044 T3 ES2884044 T3 ES 2884044T3
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87186506P | 2006-12-26 | 2006-12-26 | |
| PCT/US2007/088645 WO2008083101A1 (en) | 2006-12-26 | 2007-12-21 | Phosphoramidate alkylator prodrugs for the treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2884044T3 true ES2884044T3 (es) | 2021-12-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES07869800T Active ES2884044T3 (es) | 2006-12-26 | 2007-12-21 | Profármaco alquilante de fosforamidato para el tratamiento del cáncer |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8552048B2 (Direct) |
| EP (1) | EP2114157B1 (Direct) |
| JP (1) | JP5357049B2 (Direct) |
| ES (1) | ES2884044T3 (Direct) |
| WO (1) | WO2008083101A1 (Direct) |
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| EP2114157B1 (en) | 2006-12-26 | 2021-05-26 | ImmunoGenesis, Inc. | Phosphoramidate alkylator prodrug for the treatment of cancer |
| JP5765634B2 (ja) * | 2008-10-21 | 2015-08-19 | スレッシュホールド ファーマシューティカルズ， インコーポレイテッド | 低酸素活性化型プロドラッグを用いるがんの処置 |
| RU2013102398A (ru) * | 2010-06-28 | 2014-08-10 | Тресхолд Фармасьютикалз, Инк. | Лечение рака крови |
| KR20130045341A (ko) | 2010-07-12 | 2013-05-03 | 쓰레솔드 파마슈티컬스, 인코포레이티드 | 암 치료를 위한 저산소증 활성 프로드러그와 항혈관형성제의 투여 |
| JP2014509658A (ja) * | 2011-04-01 | 2014-04-21 | スレッショルド ファーマシューティカルズ、インク． | ガン処置方法 |
| KR20140045931A (ko) * | 2011-04-15 | 2014-04-17 | 쓰레솔드 파마슈티컬스, 인코포레이티드 | 경구 투여를 위한 단위투여량 형태 |
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| MY198613A (en) | 2015-04-02 | 2023-09-11 | Ascenta Pharmaceuticals Ltd | Nitrobenzyl derivatives of anti-cancer agents |
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| WO2019238886A1 (en) | 2018-06-13 | 2019-12-19 | University Of Dundee | Bifunctional molecules for targeting usp14 |
| EP3807272A1 (en) | 2018-06-13 | 2021-04-21 | Amphista Therapeutics Ltd | Bifunctional molecules for targeting rpn11 |
| EP3807263A1 (en) | 2018-06-13 | 2021-04-21 | Amphista Therapeutics Ltd | Bifunctional molecules for targeting uchl5 |
| KR20210064252A (ko) * | 2018-09-24 | 2021-06-02 | 시에라 온코로지, 인코퍼레이티드 | Cdc7 억제제를 포함하는 암의 치료 방법 |
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| CN118076359A (zh) * | 2021-08-27 | 2024-05-24 | 深圳艾欣达伟医药科技有限公司 | 使用th-302治疗parp抑制剂耐药的患者 |
| WO2023025291A1 (zh) | 2021-08-27 | 2023-03-02 | 深圳艾欣达伟医药科技有限公司 | 冻干制剂溶液及冻干制剂、方法和用途 |
| EP4494643A4 (en) | 2022-03-15 | 2025-09-10 | Ascentawits Pharmaceuticals Ltd | METHOD OF TREATING A PATIENT WITH BRCA MUTATION CANCER |
| US20250295677A1 (en) | 2022-04-15 | 2025-09-25 | Ascentawits Pharmaceuticals, Ltd. | Method for treating cancer by using th-302 alone or in combination with parp inhibitor |
| EP4529926A1 (en) | 2022-05-23 | 2025-04-02 | Ascentawits Pharmaceuticals, Ltd. | Method for treating cancer by combining alkylating agent prodrug and cell cycle inhibitor |
| AU2023343523A1 (en) | 2022-09-13 | 2025-03-20 | Cellis Ag | Isolated targeted delivery system for the treatment of glioma |
| WO2024061346A1 (zh) | 2022-09-22 | 2024-03-28 | 深圳艾欣达伟医药科技有限公司 | 乏氧激活的化合物在制备治疗癌症患者的药物中的用途 |
| EP4637829A1 (en) | 2022-12-20 | 2025-10-29 | Cellis Sp. z o.o. ([Ltd.] | Isolated targeted delivery system for the treatment of ovarian cancer |
| KR20250160163A (ko) | 2023-02-27 | 2025-11-11 | 아센타위츠 파마슈티컬즈 리미티드 | 용액, 동결건조 제형, 동결건조 제형 단위 패키지, 주사제, 및 주사제 제조 방법 |
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- 2007-12-21 WO PCT/US2007/088645 patent/WO2008083101A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| EP2114157B1 (en) | 2021-05-26 |
| WO2008083101A1 (en) | 2008-07-10 |
| JP2010514787A (ja) | 2010-05-06 |
| US20100183742A1 (en) | 2010-07-22 |
| JP5357049B2 (ja) | 2013-12-04 |
| US8552048B2 (en) | 2013-10-08 |
| EP2114157A4 (en) | 2013-01-23 |
| EP2114157A1 (en) | 2009-11-11 |
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