ES2883187T3 - Composiciones anticancerosas - Google Patents
Composiciones anticancerosas Download PDFInfo
- Publication number
- ES2883187T3 ES2883187T3 ES15820351T ES15820351T ES2883187T3 ES 2883187 T3 ES2883187 T3 ES 2883187T3 ES 15820351 T ES15820351 T ES 15820351T ES 15820351 T ES15820351 T ES 15820351T ES 2883187 T3 ES2883187 T3 ES 2883187T3
- Authority
- ES
- Spain
- Prior art keywords
- hpmcas
- solid dispersion
- rna
- weight
- poly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14196605 | 2014-12-05 | ||
| PCT/US2015/063671 WO2016090105A1 (fr) | 2014-12-05 | 2015-12-03 | Compositions anticancéreuses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2883187T3 true ES2883187T3 (es) | 2021-12-07 |
Family
ID=52006907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES15820351T Active ES2883187T3 (es) | 2014-12-05 | 2015-12-03 | Composiciones anticancerosas |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US10285948B2 (fr) |
| EP (2) | EP3925598A1 (fr) |
| JP (1) | JP6830892B2 (fr) |
| KR (1) | KR102387089B1 (fr) |
| CN (1) | CN106999432A (fr) |
| AR (1) | AR102925A1 (fr) |
| AU (1) | AU2015358497B2 (fr) |
| CA (1) | CA2969675C (fr) |
| CL (1) | CL2017001373A1 (fr) |
| CO (1) | CO2017005574A2 (fr) |
| CR (1) | CR20170218A (fr) |
| CY (1) | CY1124504T1 (fr) |
| DK (1) | DK3226843T3 (fr) |
| EA (1) | EA201791251A1 (fr) |
| ES (1) | ES2883187T3 (fr) |
| HR (1) | HRP20211140T1 (fr) |
| HU (1) | HUE054935T2 (fr) |
| IL (1) | IL252325A0 (fr) |
| LT (1) | LT3226843T (fr) |
| MA (1) | MA41111B1 (fr) |
| MD (1) | MD3226843T2 (fr) |
| MX (1) | MX2017007206A (fr) |
| MY (1) | MY192931A (fr) |
| NI (1) | NI201700068A (fr) |
| PH (1) | PH12017500979A1 (fr) |
| PL (1) | PL3226843T3 (fr) |
| PT (1) | PT3226843T (fr) |
| RS (1) | RS62421B1 (fr) |
| SG (1) | SG11201704386VA (fr) |
| SI (1) | SI3226843T1 (fr) |
| TW (1) | TWI709403B (fr) |
| UA (1) | UA123538C2 (fr) |
| WO (1) | WO2016090105A1 (fr) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2900224A1 (fr) | 2012-09-26 | 2015-08-05 | Aragon Pharmaceuticals, Inc. | Anti-androgènes pour le traitement du cancer de la prostate non métastatique, résistant à la castration |
| RS62421B1 (sr) * | 2014-12-05 | 2021-10-29 | Aragon Pharmaceuticals Inc | Anti-kancerogeni sastavi |
| EP3697398A1 (fr) | 2017-10-16 | 2020-08-26 | Aragon Pharmaceuticals, Inc. | Anti-androgènes destinés au traitement du cancer de la prostate résistant à la castration, non métastatique |
| WO2020144647A1 (fr) | 2019-01-10 | 2020-07-16 | Aragon Pharmaceuticals, Inc. | Composition pharmaceutique comprenant de l'apalutamide dispersé dans une compote de pomme |
| KR20210153038A (ko) | 2019-01-30 | 2021-12-16 | 아라곤 파마슈티컬스, 인코포레이티드 | 전이성 거세-민감성 전립선암의 치료를 위한 항안드로겐 |
| CN113711316A (zh) | 2019-01-30 | 2021-11-26 | 詹森药业有限公司 | 基于分子亚型治疗前列腺癌的方法 |
| WO2020239478A1 (fr) | 2019-05-28 | 2020-12-03 | Pharma Mar, S.A. | Trabectédine pour le traitement de sarcomes basé sur des marqueurs génomiques |
| CN115666565A (zh) | 2019-11-04 | 2023-01-31 | 阿拉贡药品公司 | 用于治疗具有严重肝损伤的受试者的非转移性去势抵抗性前列腺癌的雄激素受体抑制剂 |
| WO2021245285A1 (fr) | 2020-06-05 | 2021-12-09 | Janssen Pharmaceutica Nv | Méthodes de traitement du cancer de la prostate sur la base de sous-types moléculaires |
| WO2022049523A1 (fr) | 2020-09-04 | 2022-03-10 | Aragon Pharmaceuticals, Inc. | Méthodes de traitement du cancer de la prostate |
| WO2022195407A1 (fr) | 2021-03-19 | 2022-09-22 | Aragon Pharmaceuticals, Inc. | Méthodes de traitement du cancer de la prostate |
| WO2023152611A1 (fr) | 2022-02-11 | 2023-08-17 | Aragon Pharmaceuticals, Inc. | Apalutamide et relugolix pour le traitement du cancer de la prostate |
| WO2023209555A1 (fr) | 2022-04-26 | 2023-11-02 | Aragon Pharmaceuticals, Inc. | Produits médicamenteux approuvés et méthodes de traitement du cancer de la prostate |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE186913T1 (de) | 1992-03-31 | 1999-12-15 | Btg Int Ltd | 17-substituierte steroide, verwendbar bei behandlung von krebs |
| DK0901786T3 (da) | 1997-08-11 | 2007-10-08 | Pfizer Prod Inc | Faste farmaceutiske dispersioner med foröget biotilgængelighed |
| CA2400845A1 (fr) | 2000-02-21 | 2001-08-23 | Takeda Chemical Industries, Ltd. | Preparations a liberation lente contenant un compose physiologiquement actif peu soluble dans l'eau et methode de production et d'utilisation desdites preparations |
| ATE307571T1 (de) | 2001-02-27 | 2005-11-15 | Pharmazeutische formulierung enthaltend bicalutamid | |
| NZ528284A (en) | 2001-04-02 | 2005-04-29 | Astrazeneca Ab | Solid pharmaceutical composition comprising 4-cyano-trifluoro-3-(4-fluorophenylsulphonyl)-2-hydroxy-2-methylpropiono-m toluidide and PVP |
| CZ20033457A3 (cs) | 2001-06-22 | 2004-09-15 | Pfizer Products Inc. | Farmaceutická kompozice zahrnující léčiva s nízkou rozpustností a/nebo léčiva citlivá na kyselinu a neutralizované kyselé polymery |
| SE0103424D0 (sv) | 2001-10-15 | 2001-10-15 | Astrazeneca Ab | Pharmaceutical formulation |
| PL371593A1 (en) | 2002-02-01 | 2005-06-27 | Pfizer Products Inc. | Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles |
| WO2003077827A1 (fr) | 2002-03-19 | 2003-09-25 | Nippon Shinyaku Co., Ltd. | Procede de production de medicament solide en dispersion |
| CA2549572A1 (fr) | 2003-12-15 | 2005-06-23 | Council Of Scientific & Industrial Research | Compositions pharmaceutiques au gout masque comportant une medicament amer et un polymere sensible au ph |
| WO2007126765A2 (fr) | 2006-03-27 | 2007-11-08 | The Regents Of The University Of California | Modulateur de récepteur androgène pour le traitement du cancer de la prostate et de maladies associées au récepteur androgène |
| KR101739994B1 (ko) * | 2009-04-03 | 2017-05-25 | 에프. 호프만-라 로슈 아게 | 프로판-１-술폰산 ｛３-［５-（４-클로로-페닐）-１Ｈ-피롤로［２，３-ｂ］피리딘-３-카르보닐］-２，４-디플루오로-페닐｝-아미드 조성물 및 그의 용도 |
| PT3124481T (pt) | 2010-02-16 | 2018-06-18 | Aragon Pharmaceuticals Inc | Moduladores do receptor de androgénios e suas utilizações |
| CN102525876B (zh) * | 2010-12-15 | 2014-03-12 | 西安力邦医药科技有限责任公司 | 阿司匹林固体分散体、其制备方法、药物组合物和用途 |
| US10071945B2 (en) | 2011-06-15 | 2018-09-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Nuclear receptor modulators and their use for the treatment and prevention of cancer |
| US20150037407A1 (en) | 2012-03-21 | 2015-02-05 | Emphascience, Inc. | Method to improve the safety of handling of high potency drugs in solid dosage forms without changing their efficacy |
| WO2013152342A1 (fr) * | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Inhibiteur de mtor anticancéreux et combinaison anti-androgène |
| DK3348553T3 (da) * | 2012-06-07 | 2020-07-27 | Aragon Pharmaceuticals Inc | Krystallinske former af en androgen receptormodulator |
| US10668156B2 (en) | 2012-06-22 | 2020-06-02 | Basf Se | Active-ingredient-containing solid dispersions based on diethylaminoethyl methacrylate copolymers |
| WO2014031422A1 (fr) | 2012-08-24 | 2014-02-27 | Dow Global Technologies Llc | Nouveaux acétate-succinates d'hydroxyalkylméthylcellulose |
| HRP20211423T1 (hr) * | 2012-09-11 | 2022-01-21 | Medivation Prostate Therapeutics Llc | Formulacije enzalutamida |
| US9977033B2 (en) | 2012-09-11 | 2018-05-22 | The Board Of Regents Of The University Of Texas System | Methods for assessing cancer recurrence |
| EP2900224A1 (fr) * | 2012-09-26 | 2015-08-05 | Aragon Pharmaceuticals, Inc. | Anti-androgènes pour le traitement du cancer de la prostate non métastatique, résistant à la castration |
| JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
| JP6192244B2 (ja) | 2013-01-22 | 2017-09-06 | エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト | 改良されたバイオアベイラビリティを有する薬学的組成物 |
| TWI731321B (zh) | 2013-03-15 | 2021-06-21 | 阿聯商太陽法瑪全球有限公司 | 醋酸阿比特龍配方 |
| WO2014167428A2 (fr) | 2013-04-10 | 2014-10-16 | Shilpa Medicare Limited | 4-(3-(4-cyano-3-(trifluorométhyl)phényl)-5,5-diméthyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-n-méthylbenzamide amorphe |
| MX2016001901A (es) | 2013-08-12 | 2016-10-13 | Tokai Pharmaceuticals Inc | Biomarcadores para tratamiento de trastornos neoplasicos usando terapias dirigidas con andrógeno. |
| WO2015116696A1 (fr) * | 2014-01-28 | 2015-08-06 | Massachusetts Institute Of Technology | Thérapies de combinaison et procédés d'utilisation associés pour le traitement du cancer |
| US20160346207A1 (en) | 2014-02-05 | 2016-12-01 | Lek Pharmaceuticals D.D. | Solid Pharmaceutical Compositions Of Androgen Receptor Antagonists |
| NZ719654A (en) | 2014-02-06 | 2020-06-26 | Hoffmann La Roche | Interleukin-2 fusion proteins and uses thereof |
| TWI831347B (zh) | 2014-08-08 | 2024-02-01 | 日商中外製藥股份有限公司 | 包含４環性化合物的非晶質體之固體分散體及製劑 |
| RS62421B1 (sr) | 2014-12-05 | 2021-10-29 | Aragon Pharmaceuticals Inc | Anti-kancerogeni sastavi |
| MA41107A (fr) | 2014-12-05 | 2017-10-10 | Aragon Pharmaceuticals Inc | Compositions anti-cancéreuses |
| SG11201704264UA (en) | 2014-12-05 | 2017-06-29 | Aragon Pharmaceuticals Inc | Anticancer compositions |
| KR20190015314A (ko) * | 2016-06-03 | 2019-02-13 | 아라곤 파마슈티컬스, 인코포레이티드 | 항암 조성물 |
-
2015
- 2015-12-03 RS RS20211035A patent/RS62421B1/sr unknown
- 2015-12-03 SG SG11201704386VA patent/SG11201704386VA/en unknown
- 2015-12-03 EP EP21175525.1A patent/EP3925598A1/fr active Pending
- 2015-12-03 PT PT158203513T patent/PT3226843T/pt unknown
- 2015-12-03 US US15/533,229 patent/US10285948B2/en active Active
- 2015-12-03 LT LTEP15820351.3T patent/LT3226843T/lt unknown
- 2015-12-03 JP JP2017529774A patent/JP6830892B2/ja active Active
- 2015-12-03 TW TW104140459A patent/TWI709403B/zh active
- 2015-12-03 CN CN201580066235.3A patent/CN106999432A/zh active Pending
- 2015-12-03 DK DK15820351.3T patent/DK3226843T3/da active
- 2015-12-03 MY MYPI2017701986A patent/MY192931A/en unknown
- 2015-12-03 MX MX2017007206A patent/MX2017007206A/es unknown
- 2015-12-03 SI SI201531686T patent/SI3226843T1/sl unknown
- 2015-12-03 WO PCT/US2015/063671 patent/WO2016090105A1/fr active Application Filing
- 2015-12-03 EP EP15820351.3A patent/EP3226843B1/fr active Active
- 2015-12-03 MA MA41111A patent/MA41111B1/fr unknown
- 2015-12-03 UA UAA201707015A patent/UA123538C2/uk unknown
- 2015-12-03 HU HUE15820351A patent/HUE054935T2/hu unknown
- 2015-12-03 EA EA201791251A patent/EA201791251A1/ru unknown
- 2015-12-03 AU AU2015358497A patent/AU2015358497B2/en active Active
- 2015-12-03 CA CA2969675A patent/CA2969675C/fr active Active
- 2015-12-03 KR KR1020177018243A patent/KR102387089B1/ko active IP Right Grant
- 2015-12-03 CR CR20170218A patent/CR20170218A/es unknown
- 2015-12-03 PL PL15820351T patent/PL3226843T3/pl unknown
- 2015-12-03 MD MDE20170154T patent/MD3226843T2/ro unknown
- 2015-12-03 ES ES15820351T patent/ES2883187T3/es active Active
- 2015-12-04 AR ARP150103981A patent/AR102925A1/es unknown
-
2017
- 2017-05-16 IL IL252325A patent/IL252325A0/en unknown
- 2017-05-26 PH PH12017500979A patent/PH12017500979A1/en unknown
- 2017-05-29 CL CL2017001373A patent/CL2017001373A1/es unknown
- 2017-06-02 NI NI201700068A patent/NI201700068A/es unknown
- 2017-06-05 CO CONC2017/0005574A patent/CO2017005574A2/es unknown
-
2019
- 2019-03-19 US US16/357,821 patent/US11224575B2/en active Active
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2021
- 2021-03-15 US US17/201,811 patent/US11911511B2/en active Active
- 2021-07-19 HR HRP20211140TT patent/HRP20211140T1/hr unknown
- 2021-08-13 CY CY20211100730T patent/CY1124504T1/el unknown
Also Published As
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| JP6767368B2 (ja) | 抗癌性組成物 | |
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| BR112017011726B1 (pt) | Dispersão sólida, partícula, formulação farmacêutica, processo para preparação da referida dispersão bem como combinação | |
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